Results 61 to 70 of about 369,222 (166)
American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 407-418, February 2026.ABSTRACT Costello syndrome (CS) is a rare dominant HRAS RASopathy characterized by curly hair, cardiac abnormalities, craniofacial anomalies, and developmental delay. HRAS codon 58, 59, and 60 variants are associated with milder phenotypes. We describe a three‐generation family with a previously unreported heterozygous HRAS variant c.175G>A (p.Ala59Thr)
Nikole Rautiainen +10 more
wiley +1 more source
A case of acanthosis nigricans coexisting with mycosis fungoides [PDF]
, 2015 Acanthosis nigricans maligna (ANM) is a paraneoplastic phenomenon most commonly associated with visceral adenocarcinoma, in particular, gastric adenocarcinoma.
Cheng, Esther +6 more
core +1 more source
Case Reports in Dermatology, 2012 Acanthosis nigricans (AN) is a hyperpigmented keratotic skin lesion known to be associated with malignant disease and endocrinopathy. We report a very rare case of generalized AN with Sjögren’s syndrome- and systemic lupus erythematosus-like features but
Y. Kondo +5 more
doaj +1 more source
International Expert Consensus on Knowledge Gaps in Care for Dermatologic Disorders in Skin of Color
International Journal of Dermatology, Volume 65, Issue 1, Page 41-56, January 2026.State‐of‐the‐art knowledge gaps in dermatological disorders, photoprotection and procedural dermatology in individuals with skin of color (SOC). ABSTRACT Patients with skin of color (SOC) face unique dermatologic challenges that are often underrepresented in research and in dermatological education, creating critical gaps in care.
Henry W. Lim +8 more
wiley +1 more source
Acanthosis Nigricans associated with clear-cell renal cell carcinoma
Autopsy and Case Reports, 2016 Acanthosis nigricans (AN), an entity recognized since the 19th century, is a dermatopathy associated with insulin-resistant conditions, endocrinopathies, drugs, chromosome abnormalities and neoplasia.
Fernando Peixoto Ferraz de Campos +6 more
doaj +1 more source
Complex Dermatological Manifestations of Poorly Controlled Diabetes: A Case of Acquired Ichthyosis
Case Reports in Dermatological Medicine, Volume 2026, Issue 1, 2026.Acquired ichthyosis (AI) is a rare dermatological disorder characterized by dry, scaly skin. This case involves a 67‐year‐old Hispanic male with poorly controlled diabetes mellitus (DM) who presented with generalized dryness and itchiness after diabetic ketoacidosis.
Sam Fathizadeh +4 more
wiley +1 more source
A study of pathogenesis of Acanthosis nigricans and its clinical implications
Indian Journal of Dermatology, 2011 Background: Acanthosis nigricans (AN) is a dermatosis characterized by thickened, hyperpigmented plaques, typically on the intertriginous surfaces and neck. Common in some populations, its prevalence depends on race.
Neerja Puri
doaj +1 more source
Case Reports in Pathology, Volume 2026, Issue 1, 2026.Acute esophageal necrosis (AEN), also called “black esophagus,” is a rare, life‐threatening condition characterized by circumferential black discoloration of the esophageal mucosa, usually secondary to ischemia, impaired mucosal defenses, and gastric acid injury.
Kamaleldein Einar +6 more
wiley +1 more source
Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women
Clinical Endocrinology, Volume 103, Issue 4, Page 540-566, October 2025.ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan +14 more
wiley +1 more source
Deep Phenotyping of Pathology‐Confirmed Benign Lesions in PTEN Hamartoma Tumor Syndrome Patients
Clinical Genetics, Volume 108, Issue 4, Page 400-411, October 2025.Gastrointestinal, skin, thyroid, and vascular lesions are frequently present in PTEN Hamartoma Tumor Syndrome patients with little to no difference between sexes or by index status. Early‐onset lipomas (< 20 years) may be useful for early recognition of patients, and uterine polyps should be considered for inclusion as a PHTS‐related lesion.
Ane J. Schei‐Andersen +14 more
wiley +1 more source