Results 241 to 250 of about 478,842 (334)

On the Association Between Vitiligo and Malignant Melanoma

, 1998
M-A. Hedblad B. Lindelöf
openalex   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

Advanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo, Yingge Lv, Shuyu Huang, Chang Liu, Yan Ouyang, Bei Lan, Chenghao Xuan   +6 more
wiley   +1 more source

Use of imiquimod topical therapy for management of malignant melanoma positive margins. [PDF]

Front Oncol
Lewis K, Islam S, Alper DP, Carney MJ, Choi J, Leventhal J, Ariyan S, Baumann R, Olino K, Clune J.   +9 more
europepmc   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

Newly Synthesized Telmisartan-Amino Acid Conjugates Exhibit Enhanced Cytotoxic Effects in Malignant Melanoma Cells. [PDF]

Molecules
Vukadinović D, Damjanović A, Vuković M, Čudina O, Grahovac J, Dobričić V.   +5 more
europepmc   +1 more source

Predictors of psychological distress among individuals with a strong family history of malignant melanoma

, 2007
Nadine A. Kasparian, Bettina Meiser, PN Butow, John Simpson, Graham J. Mann   +4 more
openalex   +2 more sources

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

A Rare Case of Aggressive Tongue Malignant Melanoma: Clinical Presentation and Treatment Approach. [PDF]

Cureus
Ozgen M, Uygur ENE, Demiroz Abakay C, Cetintas S, Kurt M.   +4 more
europepmc   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

[18F]-FDG PET-CT in Malignant Melanoma. [PDF]

Diagnostics (Basel)
Mititelu TS, Mititelu MR, Bucurica S, Costache DO.   +3 more
europepmc   +1 more source