Results 251 to 260 of about 801,812 (294)

The Influence of Extracellular Citrate in Physiological Concentration on the Proliferation of Malignant Melanoma. [PDF]

open access: yesJ Cell Mol Med
Drexler K   +8 more
europepmc   +1 more source

Immune‐Related Prognostic Gene Identification in Lung Squamous Cell Carcinoma With the Cancer Genome Atlas Mining and Immunohistochemistry Validation

open access: yesiNew Medicine, EarlyView.
ABSTRACT Objective In the cancer microenvironment, stromal and immune cells hold clinical importance. In lung squamous cell carcinoma (LSCC), the aim of this study was to find immune‐linked gene expression that has prognostic pertinence. Methods From the Cancer Genome Atlas, this study obtained the LSCC gene expression profile.
Weijia Jiang   +5 more
wiley   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

open access: yesiNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang   +5 more
wiley   +1 more source
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Malignant Melanoma

Facial Plastic Surgery Clinics of North America, 2009
Malignant melanoma is the most lethal cutaneous neoplasm. Awareness, detection, and treatment along with sophistication of both the physician and patient are integral components to early recognition and cure of the disease. Diagnosis of melanoma at its earliest stage is crucial to outcome.
Joseph, Califano, Melonie, Nance
  +7 more sources

Malignant melanoma

Journal of the American Academy of Dermatology, 2003
In the European Community cutaneous melanoma accounts for 1 and 1.8% of cancers occurring in men and women, respectively. The incidence rate is increasing faster than that of any other tumour. Sun exposure, patient's phenotype, family history, and history of a previous melanoma are the major risk factors.
Matthew H, Kanzler, Susan M, Swetter
openaire   +4 more sources

Malignant Melanoma

Annual Review of Medicine, 1993
Malignant melanoma is the most rapidly increasing cancer in Caucasians throughout the world. The increased incidence is due to greater sun exposure arising from changes in clothing habits and life-styles over the past fifty years. Most melanomas arise in preexisting moles in sun-exposed sites and may spread rapidly via the vascular system if not ...
J A, Sanchez, W A, Robinson
openaire   +2 more sources

MALIGNANT MELANOMA

Medical Clinics of North America, 1998
The incidence of malignant melanoma is increasing at a rate greater than any other cancer occurring in humans. In this era of managed care, patients with a suspicious pigmented lesion may first present to their primary care physician for evaluation. Therefore it is mandatory that the primary care physician be capable of distinguishing between benign ...
openaire   +2 more sources

Malignant Melanoma

Plastic Surgical Nursing, 2011
"Melanoma has become a major public health problem worldwide and its incidence in individuals of European origin continues to rise. Melanoma is the third most common cancer in Australia (in men and women); the fifth in the United States (in men and women); and the 12th in men and the sixth in women in the United Kingdom" (J. G. Thompson, R. A. Scolyer,
openaire   +2 more sources

Malignant Melanoma

Dermatologic Surgery, 1996
Melanoma is being diagnosed, treated, and followed more and more by dermatologists. It is important that we understand its biology, the background behind recommended treatment protocols, and how to follow patients long-term.To highlight topics related to melanoma that are often taken for granted or misunderstood so that we can offer these patients a ...
T, Parker, J, Zitelli
openaire   +2 more sources

Malignant Melanoma

2004
PET and PET-CT in Oncology describes the principles of positron emission tomography and is a useful resource for incorporating the technique in clinical practice. In a clear and straightforward fashion, this heavily-illustrated text offers instructive information and overviews of the basic principles of PET and PET-CT as well as the routine clinical ...
Paquet, Philippe   +3 more
openaire   +2 more sources

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