Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.DCAF7 is up‐regulated in various tumours and correlates with poor prognosis, particularly in LIHC. High DCAF7 expression is linked to CD4+ T cell infiltration, up‐regulation of immune checkpoint genes and increased tumour mutational burden, suggesting a role in tumour immune escape.
Ruina Luan +6 more
wiley +1 more source
EPHA2 mutations with oncogenic characteristics in squamous cell lung cancer and malignant pleural mesothelioma. [PDF]
, 2019 Squamous cell carcinoma (SCC) and malignant pleural mesothelioma (MPM) are thoracic malignancies with very poor prognosis and limited treatment options.
Arif, Qudsia +15 more
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1090. VEGF Promoter-Based Conditionally Replicative Adenoviruses Are Useful for the Treatment of Malignant Pleural Mesothelioma [PDF]
, 2003 openalex +1 more source
Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.Application of synthetic lethality screening in drug resistance models. Abstract Background and Rationale Synthetic lethality (SL)‐based strategies hold significant promise for overcoming therapeutic resistance, a critical bottleneck in cancer treatment where cancer cells evade anticancer therapies, leading to diminished efficacy or treatment failure ...
Junyan Li +4 more
wiley +1 more source
Prognostic Factors According to the Treatment Schedule in Malignant Pleural Mesothelioma [PDF]
, 2009 Güntülü Ak +7 more
openalex +1 more source
Molecular Landscape of TP53/RB1 Co‐Altered Tumors Uncovers Emerging Therapeutic Vulnerabilities
Genes, Chromosomes and Cancer, Volume 65, Issue 1, January 2026.ABSTRACT Background Although TP53 and RB1 co‐alterations play critical roles in promoting malignant development and progression, specific inhibitors targeting this co‐alteration are lacking. We performed a pan‐cancer analysis to characterize the biology of TP53/RB1 co‐alterations and identify therapeutic strategies.
Xuetao Li +8 more
wiley +1 more source
Supplementary Figure S3 from Genomic Instability and Protumoral Inflammation Are Associated with Primary Resistance to Anti–PD-1 + Antiangiogenesis in Malignant Pleural Mesothelioma [PDF]
, 2023 François‐Xavier Danlos +42 more
openalex +1 more source
The Role of Macrophages in Cancer: From Basic Research to Clinical Applications
MedComm, Volume 7, Issue 1, January 2026.Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu +5 more
wiley +1 more source
Comments on Vimercati et al., 2019, “Asbestos exposure and malignant mesothelioma of the tunica vaginalis testis: a systematic review and the experience of the Apulia (southern Italy) mesothelioma register” [PDF]
, 2019 Gábor Mezei +3 more
openalex +1 more source
Melanoma: Pathogenesis and Targeted Therapy
MedComm, Volume 7, Issue 1, January 2026.The treatment landscape for advanced melanoma has evolved significantly. BRAF–MEK inhibitor combinations are standard for BRAF‐mutant melanoma, whereas targeting NRAS mutations is more challenging, with MEK inhibitors like tunlametinib emerging as an option.
Yang Fu +5 more
wiley +1 more source