Results 121 to 130 of about 409,422 (240)

Human biomarker navigator

iMeta, Volume 5, Issue 5, October 2026.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

When Liver Disease Misleads the Diagnosis: Two Cases of TAFRO Syndrome With Porto‐Sinusoidal Vascular Disease

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Background TAFRO syndrome is a rare inflammatory disorder whose hepatic manifestations may mimic decompensated cirrhosis. Cases: We report two women with TAFRO syndrome associated with portal‐sinusoidal vascular disorder (PSVD), a rare cause of non‐cirrhotic portal hypertension. In both cases, liver biopsy excluded cirrhosis and confirmed PSVD.
Laura Dassy, Fanny Poletti, Kaoutar Hafraoui, Marie Lejeune, Joan Somja, Patrick Collins, Julien Guiot, Ivan Theate, Jo Caers, Jean Delwaide, Astrid Marot, Virginie Putzeys, Gaëlle Vertenoeil   +12 more
wiley   +1 more source

Clinical and Molecular Features of BAP1‐Mutated Meningiomas: Case Series

Molecular Carcinogenesis, Volume 65, Issue 10, Page 1343-1350, October 2026.
ABSTRACT BRCA1‐associated protein 1 (BAP1)‐deficient meningiomas represent a clinically and molecularly distinct subgroup with variable histology and aggressive behavior that may not be fully captured by current grading criteria. The clinical spectrum of BAP1 alterations in meningiomas, including both somatic and germline contexts, remains incompletely
Ivan Pradilla, Rasha Alfattal, Susan L. McGovern, Shaan M. Raza, Franco DeMonte, Leomar Y. Ballester, Chirag B. Patel, Carlos Kamiya‐Matsuoka   +7 more
wiley   +1 more source

Malignant Epithelioid Mesothelioma of the Tunica Vaginalis Testis Presenting as Hydrocele in a Kidney Transplant Recipient

Case Reports in Urology
Mesotheliomas of the tunica vaginalis testis are rare malignant tumors that can present as a scrotal mass or hydrocele. These tumors are typically aggressive with high rates of recurrence and metastasis.
Brett M. Behers, Christopher W. Guske, Benjamin J. Behers, Spencer B. Kortum, Isabella G. Bermingham, Christina L. Warner, Robert I. Carey   +6 more
doaj   +1 more source

Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta, Ramakrishna Vadde, Ganji Purnachandra Nagaraju   +2 more
wiley   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Glutamine Metabolism in Health and Diseases

MedComm, Volume 7, Issue 10, October 2026.
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding, Fan Tong, Jing Zeng, Chun‐Ping Cui   +3 more
wiley   +1 more source

Malignant Peritoneal Mesothelioma

Chonnam Medical Journal, 2022
Fukunaga, Tomohiko, Somatomo, Yumi, Kamiyama, Jun, Kasanami, Toshihiko   +3 more
openaire   +2 more sources

Environmental Asbestos Exposure as a Possible Pathway to Early‐Onset Pleural Mesothelioma: A Case From Afghanistan and Pakistan to London

Respirology Case Reports, Volume 14, Issue 10, October 2026.
We report a case of a 40‐year‐old male with malignant pleural mesothelioma with no prior occupational exposure to asbestos. Environmental exposure as a cause of MPM may come into focus through migration from high environmental asbestos exposure regions in patients with no known occupational exposure.
Sophie Mounouchos, Asmita Aggarwal, Asaad Ahmed Nafees, Emma Johnson, Paul Cullinan, Carl Reynolds   +5 more
wiley   +1 more source

Pleural Mesothelioma With Unusual Squamous Differentiation: A Clinicopathological Case Report With Molecular Insights From Whole‐Exome Sequencing

Pathology International, Volume 76, Issue 10, October 2026.
This case report highlights a rare histological variant of pleural mesothelioma with partially squamous differentiation in an 81‐year‐old man with occupational asbestos exposure. In addition to histological, immunohistochemical and fluorescence in situ hybridization analyses, indicating a common mesothelial origin of both tumor components, whole‐exome ...
Julius Bodemeyer, Mara Elisa Mierzwa, Jörg Seraphin, Rizkallah Maroun, Wolfgang Körber, Christoph Engelke, Felix Bremmer, Tessa Rosenthal, Tim Heißenberg, Kirsten Reuter‐Jessen, Philipp Ströbel, Alexander Marx, Hanibal Bohnenberger   +12 more
wiley   +1 more source