Results 1 to 10 of about 27,683 (265)

Elevated levels of anti inflammatory IL-10 and pro inflammatory IL-17 in malignant pleural effusions [PDF]

Journal of Cardiothoracic Surgery, 2012
Background Pleural effusions can be caused by highly different underlying diseases and are characterized by complex interactions of various local and circulating cells as well as numerous soluble parameters like interleukins (IL).
Klimatsidas Michail, Anastasiadis Kyriakos, Foroulis Christophoros, Tossios Paschalis, Bisiklis Alexandros, Papakonstantinou Christos, Rammos Kyriakos   +6 more
doaj   +2 more sources

Utility of Cancer ratio (serum LDH: pleural fluid ADA) for predicting malignancy in patients with exudative pleural effusion [PDF]

Journal of Cardio-Thoracic Medicine, 2021
Introduction: Pleural effusion is an accumulation of fluid in the pleural space. It can be transudative or exudative. Mechanisms like alteration in Starling’s forces lead to transudative effusions while inflammation and infiltration by infections ...
Bhaskar Kakarla, Varaprasad Kuruva, Swaroopa Deme, Sekhar Babu Banda, Narendra Kumar Narahari, Paramjyothy Gongati Kruparao   +5 more
doaj   +1 more source

Malignant pleural effusion [PDF]

QJM, 2013
Malignant pleural effusion (MPE) refers to the presence of neoplastic cells in the pleural fluid. Approximately 40 000 people per year in the UK are affected by MPE and it is associated with significant morbidity and an overall poor prognosis. Management should be prompt and care plans should be individualized and involve a multidisciplinary team of ...
Egan, A. M., McPhillips, D., Sarkar, S., Breen, D. P.   +3 more
openaire   +3 more sources

Pleural CEA, CA-15-3, CYFRA 21-1, CA-19-9, CA-125 discriminating malignant from benign pleural effusions: Diagnostic cancer biomarkers

The International Journal of Biological Markers, 2023
Introduction There is a need for a rapid, accurate, less-invasive approach to distinguishing malignant from benign pleural effusions. We investigated the diagnostic value of five pleural tumor markers in exudative pleural effusions.
Farzaneh Fazli Khalaf, Mehrnaz Asadi Gharabaghi, Maryam Balibegloo, Hamidreza Davari, Samaneh Afshar, Behnaz Jahanbin   +5 more
doaj   +1 more source

Lumican is overexpressed in lung adenocarcinoma pleural effusions. [PDF]

, 2015
Adenocarcinoma (AdC) is the most common lung cancer subtype and is often associated with pleural effusion (PE). Its poor prognosis is attributable to diagnostic delay and lack of effective treatments and there is a pressing need in discovering new ...
Arrigoni, Giorgio, Cappellesso, Rocco, Caroccia, Brasilina, Fassina, Ambrogio, Guzzardo, Vincenza, Iori, Elisabetta, Millioni, Renato, Simonato, Francesca, Tessari, Paolo, Ventura, Laura   +9 more
core   +9 more sources

Evaluation of pleural fluid YKL-40 as a marker of malignant pleural effusion

Egyptian Journal of Chest Disease and Tuberculosis, 2015
The glycoprotein YKL-40 is synthesized both by cancer cells and by tumor-associated macrophages and plays a functional role in tumor progression. Consequently, high serum YKL-40 levels have been associated with a poor prognosis in patients with several ...
Adel Attia, Ayman Rasmy, Amal Amin, Manal Alanazi   +3 more
doaj   +1 more source

Can malignant and inflammatory pleural effusions in dogs be distinguished using computed tomography [PDF]

, 2017
Computed tomography (CT) is the primary imaging modality used to investigate human patients with suspected malignant or inflammatory pleural effusion, but there is a lack of information about the clinical use of this test in dogs.
Aquino, Bedford, Benamore, Caivano, Ceribasi, Charney, D'Angelo, Dempsey, Dubielzig, Echandi, Fossum, Gumber, Hirsch, Hung, Kawashima, Lara-Garcia, Metintas, Morrison, Mott, Müller, Nakamura, Prather, Przeździecki, Rebar, Reetz, Sahin, Smith, Swinbourne, Thrall, Traill, Tyler, Vansteenkiste, Vogtli, Waite, Wang, Yamamoto   +35 more
core   +1 more source

Bacterial Infection Elicits Heat Shock Protein 72 Release from Pleural Mesothelial Cells [PDF]

, 2013
Heat shock protein 70 (HSP70) has been implicated in infection-related processes and has been found in body fluids during infection. This study aimed to determine whether pleural mesothelial cells release HSP70 in response to bacterial infection in vitro
Bielsa, S, Brown, JS, Creaney, J, della Vergiliana, JFV, Lansley, SM, Lee, YCG, Porcel, JM, Temple, SEL, Waterer, GW   +8 more
core   +1 more source

The role of tumor necrosis factor alpha in differentiation between malignant and non malignant pleural effusion

Egyptian Journal of Chest Disease and Tuberculosis, 2016
Background: Despite the fact that Light’s criteria remain the gold standard approach in differentiating exudates from transudates, several fluid markers have been introduced for establishing the cause of pleural effusion to differentiate types of pleural
Heba M. Atef, Ali A. Okab, Gehan F. Al mehy, Mona M. El Beheisy   +3 more
doaj   +1 more source

Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions [PDF]

, 2016
The Epithelial to Mesenchymal Transition (EMT) plays a role not only in tumor metastasis but also in tumor recurrence. This process is believed to be tightly linked to the presence of Cancer Stem Cells (CSCs) however, it is still not clear which ...
Cherubini, Emanuela, Giarnieri, Enrico, Giovagnoli, Maria Rosaria, Mancini, Rita, Mariotta, Salvatore, Ricci, Alberto   +5 more
core   +1 more source