Results 11 to 20 of about 72,644 (316)
Immunotherapy in Malignant Pleural Mesothelioma [PDF]
The only registered systemic treatment for malignant pleural mesothelioma (MPM) is platinum based chemotherapy combined with pemetrexed, with or without bevacizumab. Immunotherapy did seem active in small phase II trials.
C. J. De Gooijer+3 more
semanticscholar +6 more sources
Malignant pleural mesothelioma [PDF]
Malignant mesothelioma is one of the rare tumors of pleura. One such case in a 57-year-old male, who presented with hemorrhagic pleural effusion and had no history of asbestos exposure, is reported here. The rarity, unusual presentation, and implications
Rao Sukhesh
doaj +9 more sources
Heterogeneity in Malignant Pleural Mesothelioma [PDF]
Despite advances in malignant pleural mesothelioma therapy, life expectancy of affected patients remains short. The limited efficiency of treatment options is mainly caused by inter- and intra-tumor heterogeneity of mesotheliomas.
K. Oehl, B. Vrugt, I. Opitz, M. Meerang
semanticscholar +5 more sources
Malignant pleural mesothelioma [PDF]
Despite innumerable trials of surgery, radiotherapy, and countless chemotherapeutic drugs, it is unclear whether any intervention has had a significant impact on more than a few highly selected patients with malignant pleural mesothelioma. Because most patients die of respiratory failure from extensive disease progression in the thorax, treatment ...
Hedy L. Kindler
openalex +4 more sources
Malignant pleural mesothelioma in pregnancy [PDF]
A 37-year-old pregnant woman presented at 18 weeks' gestation with unrelenting chest and shoulder pain, massive pleural effusion, and a large thoracic mass. Biopsy revealed an undifferentiated sarcomatous pleural mesothelioma. Malignant mesothelioma is a rare thoracic malignancy, which has not been described in pregnancy and appears to be minimally ...
Patrick S. Ramsey+3 more
openalex +4 more sources
Malignant pleural mesothelioma [PDF]
The incidence of malignant pleural mesothelioma (MPM) has risen for some decades and is expected to peak between 2010 and 2020. Up to now, no single treatment has been proven to be effective and death usually occurs within about 12-17 months after diagnosis. Perhaps because of this poor prognosis, early screening has incited little interest.
C. Boutin+3 more
openaire +6 more sources
Malignant pleural mesothelioma [PDF]
PURPOSE The etiology, diagnosis, staging, and management of malignant pleural mesothelioma (MPM) are reviewed, with an emphasis on clinical trials of newer approaches to first-line, second-line, and adjuvant chemotherapy.In the past decade, more effective chemotherapy regimens have been developed for patients with MPM, a rapidly progressing disease ...
Makala B. Pace, Sheree E. Chen
openaire +6 more sources
Malignant pleural mesothelioma is an aggressive malignancy with poor prognosis. Unilateral pleural effusion is frequently the initial clinical sign requiring therapeutic thoracentesis, which also offers a diagnostic opportunity.
Lorenzo Zallocco+8 more
doaj +1 more source
Perspectives on the Treatment of Malignant Pleural Mesothelioma.
A subsequent study of ...
S. Janes, D. Alrifai, D. Fennell
semanticscholar +1 more source
Malignant pleural mesothelioma: an update [PDF]
Malignant mesotheliomas are rare types of cancers that affect the mesothelial surfaces, usually the pleura and peritoneum. They are associated with asbestos exposure, but due to a latency period of more than 30 years and difficult diagnosis, most cases are not detected until they reach advanced stages.
Hajj, Glaucia N. M.+5 more
openaire +5 more sources