Results 11 to 20 of about 69,782 (261)

Immunotherapy in Malignant Pleural Mesothelioma [PDF]

Frontiers in Oncology, 2020
The only registered systemic treatment for malignant pleural mesothelioma (MPM) is platinum based chemotherapy combined with pemetrexed, with or without bevacizumab. Immunotherapy did seem active in small phase II trials. In this review, we will highlight the most important immunotherapy-based research performed and put a focus on the future of MPM. PD-
Gooijer, C.J. de, Borm, F.J., Scherpereel, A., Baas, P.   +3 more
openaire   +5 more sources

Malignant pleural mesothelioma [PDF]

European Respiratory Journal, 1998
The incidence of malignant pleural mesothelioma (MPM) has risen for some decades and is expected to peak between 2010 and 2020. Up to now, no single treatment has been proven to be effective and death usually occurs within about 12-17 months after diagnosis. Perhaps because of this poor prognosis, early screening has incited little interest.
C, Boutin, M, Schlesser, C, Frenay, P, Astoul   +3 more
openaire   +4 more sources

Malignant pleural mesothelioma [PDF]

American Journal of Health-System Pharmacy, 2012
PURPOSE The etiology, diagnosis, staging, and management of malignant pleural mesothelioma (MPM) are reviewed, with an emphasis on clinical trials of newer approaches to first-line, second-line, and adjuvant chemotherapy.In the past decade, more effective chemotherapy regimens have been developed for patients with MPM, a rapidly progressing disease ...
Sheree E, Chen, Makala B, Pace
  +7 more sources

Malignant Pleural Mesothelioma: A Comprehensive Review. [PDF]

J Clin Med
Mesotheliomas are hyperplastic tumors that envelop the serosal membranes that safeguard the body’s external surfaces. Although certain instances may exhibit indolent characteristics, a significant number of tumors demonstrate rapid progression and a poor
Jain M, Crites MK, Rich P, Bajantri B.
europepmc   +2 more sources

Epidemiological, therapeutic, and survival trends in malignant pleural mesothelioma: A review of the National Cancer Database

Cancer Medicine, 2023
Malignant pleural mesothelioma (MPM) is an aggressive cancer of the cells lining the pleural cavity with a low overall incidence. The National Cancer Database (NCDB) released in August 2022 updated data that reflect the newest trends in MPM.
P. Bou-Samra, Austin Chang, F. Azari, G. Kennedy, Alix Segil, Emily Guo, M. Marmarelis, C. Langer, S. Singhal   +8 more
semanticscholar   +1 more source

Comparison of 3 Randomized Clinical Trials of Frontline Therapies for Malignant Pleural Mesothelioma

JAMA Network Open, 2022
Key Points Question Are frontline therapies recommended for malignant pleural mesothelioma (MPM) associated with patient benefits? Findings In this comparative effectiveness study of 1501 participants, the statistical robustness of the Mesothelioma ...
Tomer Meirson, F. Pentimalli, F. Cerza, Giovanni Baglio, S. Gray, P. Correale, M. Krstic-Demonacos, G. Markel, Antonio Giordano, D. Bomze, L. Mutti   +10 more
semanticscholar   +1 more source

ERS/ESTS/EACTS/ESTRO guidelines for the management of malignant pleural mesothelioma.

European Journal of Cardio-Thoracic Surgery, 2020
The European Respiratory Society (ERS)/European Society of Thoracic Surgeons (ESTS)/European Association for Cardio-Thoracic Surgery (EACTS)/European Society for Radiotherapy and Oncology (ESTRO) task force brought together experts to update previous ...
I. Opitz, A. Scherpereel, T. Berghmans, I. Psallidas, M. Glatzer, D. Rigau, P. Astoul, S. Bölükbas, Jeanette Boyd, J. Coolen, Charlotte De Bondt, D. de Ruysscher, V. Durieux, C. Faivre-Finn, D. Fennell, F. Galateau-Salle, L. Greillier, M. A. Hoda, W. Klepetko, A. Lacourt, P. McElnay, N. Maskell, L. Mutti, J. Pairon, P. V. Van Schil, J. V. van Meerbeeck, D. Waller, W. Weder, P. Putora, G. Cardillo   +29 more
semanticscholar   +2 more sources

Epidemiology and Clinical Aspects of Malignant Pleural Mesothelioma

Cancers, 2021
Simple Summary Mesothelioma is a cancer of the lining of the lungs caused by breathing in asbestos fibres. Asbestos was widely used in industry in the last century in most developed countries and is still present in many older buildings to this day ...
F. Brims
semanticscholar   +1 more source

Perspectives on the Treatment of Malignant Pleural Mesothelioma.

New England Journal of Medicine, 2021
A subsequent study of ...
S. Janes, D. Alrifai, D. Fennell
semanticscholar   +1 more source

Epidemiology, diagnosis and treatment of the malignant pleural mesothelioma, a narrative review of literature

Journal of Thoracic Disease, 2021
The malignant pleural mesothelioma is a very aggressive tumor which is arising from mesothelial cells and is associated with asbestos exposure. It is a heterogeneous cancer that shows a complex pattern of molecular changes, including genetic, chromosomic,
S. Schumann, G. Kocher, F. Minervini
semanticscholar   +1 more source