The Immune Microenvironment of Malignant Pleural Mesothelioma: A Literature Review
Simple Summary Malignant pleural mesothelioma is a rare and aggressive tumour, associated with asbestos exposure. Current therapeutic approaches for malignant mesothelioma are mainly based on systemic chemotherapy with a median overall survival of less ...
Anne-Laure Désage +3 more
semanticscholar +1 more source
Can malignant and inflammatory pleural effusions in dogs be distinguished using computed tomography [PDF]
Computed tomography (CT) is the primary imaging modality used to investigate human patients with suspected malignant or inflammatory pleural effusion, but there is a lack of information about the clinical use of this test in dogs.
Aquino +35 more
core +1 more source
Role of interleukin-6 (IL-6) in diagnosis of malignant pleural mesothelioma
Aim of the work: To evaluate the role of interleukin-6 (IL-6) in diagnosis of malignant pleural mesothelioma by detecting its level in the pleural fluid and serum of the patient with malignant pleural mesothelioma in comparison with other causes of ...
Rehab El Sayed +4 more
doaj +1 more source
Mesothelioma and thymic tumors: Treatment challenges in (outside) a network setting [PDF]
The management of patients with mesothelioma and thymic malignancy requires continuous multidisciplinary expertise at any step of the disease. A dramatic improvement in our knowledge has occurred in the last few years, through the development of ...
Girard, N +4 more
core +1 more source
Context Malignant mesothelioma is an insidious neoplasm, with malignant pleural mesothelioma as the most common type, which is characterized by poor prognosis in most patients owing to late presentation. The use of noninvasive markers for early diagnosis
Mona M Ahmed +3 more
doaj +1 more source
Survival prediction in mesothelioma using a scalable lasso regression model: instructions for use and initial performance using clinical predictors [PDF]
Introduction: Accurate prognostication is difficult in malignant pleural mesothelioma (MPM). We developed a set of robust computational models to quantify the prognostic value of routinely available clinical data, which form the basis of published MPM ...
Blyth, Kevin G. +5 more
core +1 more source
Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment
Malignant pleural mesothelioma is an aggressive malignancy of the pleural surface, predominantly caused by prior asbestos exposure. There is a global epidemic of malignant pleural mesothelioma underway, and incidence rates are predicted to peak in the ...
Anna C. Bibby +7 more
doaj +1 more source
Genomic profiling of malignant peritoneal mesothelioma reveals recurrent alterations in epigenetic regulatory genes BAP1, SETD2, and DDX3X. [PDF]
Malignant mesothelioma is a rare cancer that arises from the mesothelial cells that line the pleural cavity and less commonly from the peritoneal lining of the abdomen and pelvis.
Bastian, Boris C +10 more
core +2 more sources
Development of precision medicine for malignant pleural mesothelioma (MPM) requires a deep knowledge of tumor heterogeneity. Histologic and molecular classifications and histo‐molecular gradients have been proposed to describe heterogeneity, but a deeper
Lisa Quetel +20 more
semanticscholar +1 more source
Early Contrast Enhancement: a novel Magnetic Resonance Imaging biomarker of pleural malignancy [PDF]
Introduction: Pleural Malignancy (PM) is often occult on subjective radiological assessment. We sought to define a novel, semi-objective Magnetic Resonance Imaging (MRI) biomarker of PM, targeted to increased tumour microvessel density (MVD) and ...
Alexander, Laura +10 more
core +1 more source

