Results 61 to 70 of about 5,196,368 (357)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Macrophages and Metabolic Reprograming in the Tumor Microenvironment

Frontiers in Oncology, 2022
Due to the emergence of traditional drug resistance in tumor treatment, the anti-cancer therapies are facing multiple challenges. Immunotherapy, as a new and universal treatment, has been gradually concerned.
Jin Liu, Jin Liu, Jin Liu, Mingwei Gao, Zhou Yang, Yidan Zhao, Kun Guo, Kun Guo, Binwen Sun, Binwen Sun, Zhenming Gao, Zhenming Gao, Zhenming Gao, Liming Wang, Liming Wang, Liming Wang   +15 more
doaj   +1 more source

The role of the Bmi1-GSK3β pathway in glioblastoma [PDF]

, 2010
Malignant gliomas remain one of the deadliest of all cancers despite maximal therapy. They present unique challenges to therapy with a median survival of 12 months.
Korur, Serdar
core   +1 more source

Malignant Phyllodes Tumor

The Breast Journal, 2001
The study aims to evaluate the survival and prognosis of patients with malignant phyllodes tumor. Between 1982 and 1998, 37 women with malignant phyllodes tumor were treated at the Regional Cancer Center, Trivandrum. Twelve patients were recurrent. Survival was estimated using the Kaplan-Meier method.
M, Pandey, A, Mathew, J, Kattoor, E K, Abraham, B S, Mathew, B, Rajan, K M, Nair   +6 more
openaire   +2 more sources

CBTRUS Statistical Report: Pediatric Brain Tumor Foundation Childhood and Adolescent Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014-2018.

Neuro-Oncology, 2022
The CBTRUS Statistical Report: Pediatric Brain Tumor Foundation Childhood and Adolescent Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014-2018 comprehensively describes the current population-based incidence of
Q. Ostrom, M. Price, Katherine Ryan, J. Edelson, C. Neff, G. Cioffi, K. Waite, C. Kruchko, J. Barnholtz-Sloan   +8 more
semanticscholar   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Single-cell RNA sequencing reveals the landscape of the cellular ecosystem of primary hepatocellular carcinoma

Cancer Cell International
Hepatocellular carcinoma (HCC) cells, along with multiple nonmalignant stromal cells, such as fibroblasts, endothelial cells and immune cells, comprise an intricate cellular ecosystem, undergo dynamic phenotypic changes and present complicated cellular ...
Zeli Yin, Yilin Song, Liming Wang
doaj   +1 more source

A case report of a rare intramuscular granular cell tumor [PDF]

, 2015
Background: Granular cell tumors (GCTs) were firstly described by Weber in 1854 and 70 years later by Abrikossoff and classified as benign tumors. Originally considered muscle tumors, they have been identified as neural lesions, due to their close ...
Cacciotti, Jessica, Cirenza, Mirko, DELLA ROCCA, Carlo, Labate, Agata, Laghi, Andrea, Lo Schiavo, Maria Grazia, Mazzitelli, Riccardo, Petrozza, Vincenzo, Porta, Natale   +8 more
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

A prognostic model for overall survival in recurrent glioma patients treated with bevacizumab-containing therapy

Discover Oncology
Predictive markers and prognostic models are useful for the individualization of cancer treatment. In this study, we sought to identify clinical and molecular factors to predict overall survival in recurrent glioma patients receiving bevacizumab ...
Shanmu Jin, Wenlin Chen, Xiaopeng Guo, Hao Xing, Huiyu Yang, Qianshu Liu, Delin Liu, Kun Zhang, Hai Wang, Yu Xia, Siying Guo, Yaning Wang, Yixin Shi, Yilin Li, Yuekun Wang, Junlin Li, Jiaming Wu, Tingyu Liang, Tian Qu, Huanzhang Li, Tianrui Yang, Yu Wang, Wenbin Ma   +22 more
doaj   +1 more source