Results 41 to 50 of about 5,196,368 (357)

Histological and molecular glioblastoma, IDH-wildtype: a real-world landscape using the 2021 WHO classification of central nervous system tumors

Frontiers in Oncology, 2023
IntroductionGlioblastoma (GBM), the most lethal primary brain malignancy, is divided into histological (hist-GBM) and molecular (mol-GBM) subtypes according to the 2021 World Health Organization classification of central nervous system tumors. This study
Xiaopeng Guo, Xiaopeng Guo, Lingui Gu, Yilin Li, Yilin Li, Zhiyao Zheng, Zhiyao Zheng, Zhiyao Zheng, Wenlin Chen, Yaning Wang, Yuekun Wang, Hao Xing, Yixin Shi, Yixin Shi, Delin Liu, Delin Liu, Tianrui Yang, Tianrui Yang, Yu Xia, Yu Xia, Junlin Li, Junlin Li, Jiaming Wu, Jiaming Wu, Kun Zhang, Kun Zhang, Tingyu Liang, Hai Wang, Qianshu Liu, Qianshu Liu, Shanmu Jin, Shanmu Jin, Tian Qu, Tian Qu, Siying Guo, Siying Guo, Huanzhang Li, Huanzhang Li, Yu Wang, Yu Wang, Wenbin Ma, Wenbin Ma   +41 more
doaj   +1 more source

Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling. [PDF]

, 2016
The tumor microenvironment (TME) exerts critical pro-tumorigenic effects through cytokines and growth factors that support cancer cell proliferation, survival, motility and invasion.
Flashner-Abramson, E, Karin, M, Levitzki, A, Sanchez-Lopez, E, Shalapour, S, Taniguchi, K, Zhong, Z   +6 more
core   +1 more source

Contemporary Management of Benign and Malignant Parotid Tumors

Frontiers in Surgery, 2018
To report the standard of care, interesting new findings and controversies about the treatment of parotid tumors. Relevant and actual studies were searched in PubMed and reviewed for diagnostics, treatment and outcome of both benign and malignant tumors.
J. Thielker, M. Grosheva, S. Ihrler, A. Wittig, O. Guntinas-Lichius   +4 more
semanticscholar   +1 more source

Circulating Cell-Free DNA in Dogs with Mammary Tumors: Short and Long Fragments and Integrity Index [PDF]

, 2017
Circulating cell-free DNA (cfDNA) has been considered an interesting diagnostic/prognostic plasma biomarker in tumor-bearing subjects. In cancer patients, cfDNA can hypothetically derive from tumor necrosis/apoptosis, lysed circulating cells, and some ...
A Asmarinah, A Fawzy, A Jemal, A Matos, Alessandro Sammarco, Andrea Saccani, Antonio Mollo, BG Wang, BT Kurien, C Alix-Panabières, C Qian, CH Lee, Chiara Bedin, Chiara Romualdi, D Bostock, D El-Gayar, D Madhavan, D Merlo, Davide Trez, DMW Schaefer, Donato Nitti, E Coustan-Smith, E Gormally, EM Tan, F Salvianti, FH Igney, GB Gelaleti, Giorgia Beffagna, H Schwarzenbach, H Schwarzenbach, J Beck, J Ferlay, JC Thompson, K Jung, K Pilichou, K Sorenmo, K Sorenmo, Kristy L. Richards, KS Borge, L Ouyang, L Pena, L Pena, Laura Cavicchioli, LE Lowes, M Agostini, M Geng, M Goldschmidt, M Shackleton, M Stroun, M Stroun, Marco Agostini, Marta Mainenti, MB Giacona, Michelangelo Campanella, MV Jain, N Sleeckx, N Umetani, N Umetani, P Anker, P Hofman, P Rivera, R Agassi, R Brodey, R Kumaraguruparan, R Kumaraguruparan, Raffaella De Maria, Re Ellsworth, S Baspinar, S Cargnin, S Iqbal, S Jahr, S Volik, SA Leon, Silvia Ferro, T Hao, T Imamura, T Skvortsova, Valentina Zappulli, W Ayala, W Wang   +79 more
core   +10 more sources

Sentinel lymph node in early stage ovarian cancer; a literature review [PDF]

, 2018
Although sentinel lymph node mapping has been widely implemented in gynecological malignancies in order to minimize the number of unnecessary lymph node dissections and to diminish postoperative morbidity rate, little is known about ovarian cancer ...
Bacalbasa, Nicolae, Balescu, Irina, Brasoveanu, Vladislav, Brezean, Iulian, Vilcu, Mihaela   +4 more
core   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

EPHX1 enhances drug resistance to regorafenib by activating the JAK/STAT signaling pathway in hepatocellular carcinoma cell lines

Hereditas
Background Regorafenib serves as a second-line treatment for patients with advanced hepatocellular carcinoma (HCC). Microsomal epoxide hydrolase 1 (EPHX1) is closely associated with tumorigenesis and drug resistance.
Bin Xu, Xiangnan Liang, Wuguang Liu, BaiTong Wu, Qiuxiang Wang, Gong Kai, Chun Han, Binwen Sun, Bing Dong, Chengyong Dong, Liming Wang   +10 more
doaj   +1 more source

Primary cerebellopontine angle melanocytoma: review. [PDF]

, 2012
Introduction Primary cerebellopontine angle melanocytomas (PCPAMs) are very rare. Their natural history and prognosis are not fully understood. We reviewed the literature and add a new case to analyze PCPAM's presentation, radiological features, and ...
Elashaal, R, Eljamel, S, Ironside, J, Phang, I   +3 more
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

New molecular mediators in tumor angiogenesis [PDF]

, 2007
Angiogenesis is essential for tumor growth and progression. It has been demonstrated that tumor growth beyond a size 1 to 2 mm3 requires the induction of new vessels.
Beecken, Wolf-Dietrich, Jonas, Dietger, Kramer, Wolfgang   +2 more
core   +1 more source