Results 91 to 100 of about 429 (126)
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Cytotoxic and Antitumor Constituents in Pericarps ofMallotus japonicus
Planta Medica, 1990A variety of phloroglucinol derivatives isolated from the pericarps of Mallotus japonicus were assessed for growth inhibiting activity against human larynx (HEp-2) and lung (PC-13) carcinoma cells as well as mouse B16 melanoma, leukemia P388, and L5178Y cells. Most of these derivatives were proved to be significantly cytotoxic in culture.
M, Arisawa +3 more
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Journal of Natural Medicines, 2021
Accumulation of advanced glycation end products (AGEs) plays an important role in diabetes, immunoinflammation, and cardiovascular and neurodegenerative diseases. Since AGEs mediate their pathological effects through interaction with receptor for AGEs (RAGE), RAGE antagonists would provide a useful therapeutic option for various health disorders ...
Teruki Matsumoto +7 more
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Accumulation of advanced glycation end products (AGEs) plays an important role in diabetes, immunoinflammation, and cardiovascular and neurodegenerative diseases. Since AGEs mediate their pathological effects through interaction with receptor for AGEs (RAGE), RAGE antagonists would provide a useful therapeutic option for various health disorders ...
Teruki Matsumoto +7 more
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Studies on Cytotoxic Constituents in Pericarps of Mallotus japonicus, Part II
Journal of Natural Products, 1985Two new phloroglucinol derivatives, mallotolerin (8) and mallotochromanol (9), were isolated from the cytotoxic fraction of the pericarps of Mallotus japonicus. The new derivatives were identified as 3-(3-methyl-2-hydroxybut-3-enyl)-5-(3-acetyl-2,4-dihydroxy-5-me thy l-6- methoxybenxyl)-phlorbutyrophenone (8) and 8-acetyl-5,7-dihydroxy-6-(3-acetyl-2,4 ...
M, Arisawa +6 more
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Structure and biosynthesis of malloprenols from Mallotus japonicus
Phytochemistry, 1980Abstract The mallo prenol isolated from the leaves of Mallotus japonicus was elucidated to be a mixture of (2Z,6Z, 10Z, 14Z, 18Z, 22Z, 26E, 30E, 34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-ol and its C45- and C55-homologues and not the previously reported structure.
Takayuki Suga +2 more
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Phenol glucoside gallates from Mallotus japonicus
Phytochemistry, 1989Abstract Five phenol glucoside gallates were isolated from Mallotus japonicus , and their structures characterized by chemical and spectroscopic means as 4-hydroxy-2-methoxyphenol 1- O -β- d -(6′- O -galloyl)glucoside, 4-hydroxy-3-methoxyphenol 1- O -β- d -(2′,6′-di- O -galloyl)glucoside, 4-hydroxy-3-methoxyphenol 1- O -β- d -2′,3′,6′-tri- O ...
Reiko Saijo +2 more
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Phloroglucinol derivatives from fruits of Mallotus japonicus
Phytochemistry, 1983Abstract Two new rottlerin-like phloroglucinol derivatives were isolated from the fruits of Mallotus japonicus and identified by chemical and spectral data as 3-(3, 3-dimethylallyl)-5-(3-acetyl-2, 4-dihydroxy-5-methyl-6-methoxybenzyl)-phloracetophenone and 3-(3-methyl-2-hydroxybut-3-enyl)-5-(3-acetyl-2, 4-dihydroxy-5-methyl-6-methoxybenzyl ...
Nobuharu Shigematsu +2 more
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Further phloroglucinol derivatives in the fruits of Mallotus japonicus
Phytochemistry, 1985Abstract Two new rottlerin-like phloroglucinol derivatives were detected from the fruits of Mallotus japonicus and identified as 3-(3,3-dimethylallyl)-5-(3-acetyl-2,4-dihydroxy-5-methyl-6-methoxybenzyl)-phlorobutyrophenone and -phloroisobutyrophenone by spectral studies.
Isao Kouno +3 more
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