Results 141 to 150 of about 605,051 (424)

Population pharmacokinetics and dosing of dispersible moxifloxacin formulation in children with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Moxifloxacin is a priority drug for treating rifampicin‐resistant tuberculosis (RR‐TB). We assessed the pharmacokinetics of a child‐friendly, dispersible 100 mg tablet moxifloxacin formulation (dispersed in water) compared to the standard 400 mg non‐dispersible formulation (crushed and suspended in water) in children and evaluated current dosing ...
Megan Palmer, Yuanxi Zou, Anneke C. Hesseling, Louvina van der Laan, Ingrid Courtney, Aarti A. Kinikar, Naresh Sonkawade, Mandar Paradkar, Vandana Kulkarni, Dessa Jean O. Casalme, Melchor V. G. Frias, Heather Draper, Lubbe Wiesner, Mats O. Karlsson, Paolo Denti, Elin M. Svensson, Anthony J. Garcia‐Prats   +16 more
wiley   +1 more source

Effect of hydration schedules on dose‐limiting toxicity in patients with head and neck squamous cell carcinoma treated with cisplatin

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of this study was to determine if head and neck squamous cell carcinoma (HNSCC) patients treated with cisplatin chemoradiotherapy and short hydration (SH) experience less dose‐limiting toxicity (DLT) and receive more cisplatin than those with medium hydration (MH) or long hydration (LH).
Anouk W. M. A. Schaeffers, Cassimy B. van Neerven, Dorieke van Balen, Mirjam Crul, Marije Slingerland, Saskia A. C. Luelmo, Jan Paul de Boer, Jens Voortman, Arjan D. van Zuilen, Remco de Bree, Lot A. Devriese   +10 more
wiley   +1 more source

An observation on the bias in clinic-based estimates of malnutrition rates [PDF]

Clinic-based data on malnutrition are the most readily available for following malnutrition levels and trends in most countries, but there is a bias inherent in clinic-based estimates of malnutrition rates.
Fox, Kristin, Grosh, Margaret E., Jackson, Maria   +2 more
core  

Risk Factors for Malnutrition in Older Adults: A Systematic Review of the Literature Based on Longitudinal Data.

Advances in Nutrition, 2016
The present systematic review critically examines the available scientific literature on risk factors for malnutrition in the older population (aged ≥65 y).
Nádia Cristina Fávaro-Moreira, S. Krausch-Hofmann, C. Matthys, C. Vereecken, Erika Vanhauwaert, Anja Declercq, G. Bekkering, J. Duyck   +7 more
semanticscholar   +1 more source

Paracetamol and its metabolites in children and adults with spinal muscular atrophy – a population pharmacokinetic model

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao, Marie Mostue Naume, Brenda C. M. de Winter, Thomas Krag, Sissel Sundell Haslund‐Krog, Karoline Lolk Revsbech, John Vissing, Helle Holst, Morten Hylander Møller, Tessa Munkeboe Hornsyld, Morten Dunø, Christina Engel Hoei‐Hansen, Alfred Peter Born, Per Bo Jensen, Mette Cathrine Ørngreen   +14 more
wiley   +1 more source

MALNUTRITION WITH MICROCARDIA [PDF]

American Journal of Roentgenology, 1967
Roentgenographic microcardia or a shrinking cardiac silhouette observed on serial chest roentgenograms was associated with pathologic cardiac atrophy in 18 of 21 patients. Microscopic and gross pathologic study classified 17 hearts as brown atrophy, 4 as simple atrophy, with 3 specimens unclassified. The relationship of malnutrition and chronic illness
openaire   +3 more sources

Acute Malnutrition and Under-5 Mortality, Northeastern Part of India. [PDF]

, 2010
We assessed the prevalence of childhood acute malnutrition and under-five mortality rate (U5MR) in Darbhanga district, India, using a two-stage 49-cluster household survey. A total of 1379 households comprising 8473 people were interviewed.
Boss, C. Roure Pujol, E. Espie, Gupta, J.-F. Saint-Sauveur, Lahariya, M. Masferrer, P. P. Palma Urrutia, R. F. Grais, Yadav, Yadav   +10 more
core   +2 more sources

Evaluating the effectiveness of training on malnutrition for Anganwadi workers in Anekal Taluk, Bengaluru Urban District

Journal of Family Medicine and Primary Care
Background: Post COVID-19 pandemic, due to lack of access to nutritional services, malnutrition prevalence has exacerbated. The role of Anganwadi workers in provision of nutrition services is important in prevention of malnutrition in the community. Aim:
Nancy Angeline Gnanaselvam, Avita Rose Johnson, Anupama Shetty   +2 more
doaj   +1 more source

Medications, epilepsy and climate change: Added layers of complexity

British Journal of Clinical Pharmacology, EarlyView.
Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi, Seyhmus Gavas, Sanjay M. Sisodiya   +2 more
wiley   +1 more source

Malnutrition and infection

Medicine, 2001
Abstract The term ‘malnutrition' usually refers to macronutrient malnutrition, though individuals may also be malnourished in terms of micronutrients. Worldwide, it is commonly associated with poverty. Malnutrition is a risk factor that increases susceptibility to and severity of infections by its effects on both innate and adaptive immunity.
openaire   +2 more sources