Results 11 to 20 of about 4,909 (228)

Probing the Binding Requirements of Modified Nucleosides with the DNA Nuclease SNM1A

Molecules, 2021
SNM1A is a nuclease that is implicated in DNA interstrand crosslink repair and, as such, its inhibition is of interest for overcoming resistance to chemotherapeutic crosslinking agents.
Eva-Maria Dürr, Joanna F. McGouran
doaj   +1 more source

Synthesis of novel β-aminocyclobutanecarboxylic acid derivatives by a solvent-free aza-Michael addition and subsequent ring closure [PDF]

, 2011
Novel beta-aminocyclobutanecarboxylic acid derivatives were prepared via a sequential solvent-free aza-Michael addition of benzophenone imine across 3-halopropylidenemalonates and base-induced ring closure.
Aitken, Appella, Brannock, Caine, Choudhary, Declerck, Fernandes, Fernandes, Fernandes, Frackenpohl, Fülöp, Fülöp, Gademann, Gauzy, Gauzy, Gellman, Gorrea, Hall, Imanzadeh, Izquierdo, Kiss, Krapcho, Kuhl, Lehnert, Liu, Mangelinckx, Mangelinckx, Mangelinckx, Mangelinckx, Martinek, Martín-Vilà, Mittendorf, Norbert De Kimpe, Oki, Palko, Rúa, Seebach, Seebach, Su, Sulmon, Sven Mangelinckx, Tamara Meiresonne, Torres, Trabocchi, White   +44 more
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Cyclooctyne [60]fullerene hexakis adducts: a globular scaffold for copper-free click chemistry [PDF]

, 2016
The synthesis of a new highly symmetric hexakis adduct of C60 appended with 12 cyclooctyne moieties has been carried out. This compound has been used for the copper-free strain-promoted cycloaddition reaction to a series of azides with excellent yields ...
Illescas, Beatriz M., Martín, Nazario, Pérez-Sánchez, Alfonso, Ramos-Soriano, Javier, Reina, José J., Rojo, Javier   +5 more
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The Allylic Alkylation of Ketone Enolates

ChemistryOpen, 2020
The palladium‐catalyzed allylic alkylation of non‐stabilized ketone enolates was thought for a long time to be not as efficient as the analogous reactions of stabilized enolates, e. g. of malonates and β‐ketoesters.
Dr. Lukas Junk, Prof. Dr. Uli Kazmaier
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Tandem Three-Component Reactions of Aldehyde, Alkyl Acrylate, and Dialkylmalonate Catalyzed by Ethyl Diphenylphosphine

Molecules, 2012
A new highly efficient three-component reaction of alkyl acrylate, aldehyde and dialkyl malonate using ethyl diphenylphosphine as organocatalyst has been described.
Utpal Das, Ko-Wei Chen, Chia-Jui Lee, Yu-Ting Lee, Yi-Wun Jhang, Siang-En Syu, Yeong-Jiunn Jang, Wenwei Lin   +7 more
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Electrochemical Perspective on Hematite–Malonate Interactions

Colloids and Interfaces, 2021
Organic matter (OM) interactions with minerals are essential in OM preservation against decomposition in the environment. Here, by combining potentiometric and electrophoretic measurements, we probed the mode of coordination and the role of pH-dependent ...
Karolina Kędra, Marzena Łazarczyk, Tajana Begović, Danijel Namjesnik, Karolina Lament, Wojciech Piasecki, Piotr Zarzycki   +6 more
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Overturning established chemoselectivities : selective reduction of arenes over malonates and cyanoacetates by photoactivated organic electron donors [PDF]

, 2013
The prevalence of metal-based reducing reagents, including metals, metal complexes, and metal salts, has produced an empirical order of reactivity that governs our approach to chemical synthesis.
Asensio X., Atherton N. M., Baizer M. M., Benkeser R. A., Bhaskar Mondal, Birch A. J., Bodnar B. S., Bouveault L., Cahard E., Carbery D. R., Cram D. J., Cutulic S. P. Y., Cutulic S. P. Y., Doni E., Eswararao Doni, Finley K. T., Fischer H., Garnier J., Garnier J., Garnier J., Hunter C. A., John A. Murphy, Jolly P. I., Kang H.-Y., Kohn W., Krishnan R., Krollpfeiffer F., Lam K., Lam K., Maslak P., Maslak P., McLean A. D., Mortensen J., Murphy J. A., Murphy J. A., Murphy J. A., Murphy J. A., Murphy J. A., Newcomb M., Parmar D., Parr R. G., Portella C., Rühlmann K., S. Grimme S., Sautier B., Steven O’Sullivan, Studer A., Sword R., Szostak M., Tanko J. M., Tell Tuttle, Tomasi J., Xu Q.   +52 more
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One-pot asymmetric cyclocarbohydroxylation sequence for the enantioselective synthesis of functionalised cyclopentanes [PDF]

, 2010
International audienceA new method has been developed for the enantioselective synthesis of highly functionalised cyclopentanes bearing up to three stereogenic centres with very high stereoselectivity.
Bonne, Damien, Dulcère, Jean-Pierre, Lettieri, Grégory, Raimondi, Wilfried, Rodriguez, Jean   +4 more
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Synthesis of Bicyclic Isoxazoles and Isoxazolines via Intramolecular Nitrile Oxide Cycloaddition

Molecules, 2015
An efficient and straight forward procedure for the syntheses of bicyclic isoxazole/isoxazoline derivatives from the corresponding dimethyl-2-(2-nitro-1-aryl/alkyl)-2-(prop-2-yn-1yl)malonates or dimethyl 2-allyl-2-(2-nitro-1-aryl/alkyl ethyl)malonate is ...
Wen-Chang Chen, Veerababurao Kavala, Yu-Hsuan Shih, Yu-Hsuan Wang, Chun-Wei Kuo, Tang-Hao Yang, Chia-Yu Huang, Hao-Hsiang Chiu, Ching-Fa Yao   +8 more
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Recoverable Phospha-Michael Additions Catalyzed by a 4-N,N-Dimethylaminopyridinium Saccharinate Salt or a Fluorous Long-Chained Pyridine: Two Types of Reusable Base Catalysts

Molecules, 2021
Phospha-Michael addition, which is the addition reaction of a phosphorus-based nucleophile to an acceptor-substituted unsaturated bond, certainly represents one of the most versatile and powerful tools for the formation of P-C bonds, since many different
Eskedar Tessema, Vijayanath Elakkat, Chiao-Fan Chiu, Jing-Hung Zheng, Ka Long Chan, Chia-Rui Shen, Peng Zhang, Norman Lu   +7 more
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