Results 31 to 40 of about 1,370 (185)
SynOpen, 2017 α-Aryl malonate and α-aryl cyano acetate moieties are found in the structures of many bioactive compounds. They are also key intermediates for the synthesis of many compounds such as isoflavonoids.
José F. Cívicos +2 more
doaj +1 more source
Oocyte–cumulus cell interaction: a key factor in early embryo development
Biological Reviews, EarlyView.ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido +2 more
wiley +1 more source
Organocatalytic Formal (3+2+1)‐Cycloaddition of Allenoates, Michael Acceptors, and Carbaldehydes
Chemistry – A European Journal, EarlyView.The use of secondary amine Lewis base organocatalysts allows for the unprecedented activation of allenoates for formal (3+2+1)‐cycloadditions with Michael acceptors and aromatic carbaldehydes. ABSTRACT Employing secondary amines as covalently interacting Lewis basic organocatalysts allows for the activation of electron‐deficient allenes (allenoates ...
David Naderer +5 more
wiley +1 more source
Oxidative Generation and Reactivity of the Cyclopropyl Radical From a Martin Silicate
Chemistry – A European Journal, EarlyView.A photoredox strategy employing Martin silicates enables the oxidative generation and controlled capture of cyclopropyl radicals, including the naked one, long considered challenging intermediates. The method affords functionalized cyclopropanes through both Giese‐type additions and dual nickel/photoredox C(sp3)−C(sp2) cross‐couplings.
Amal Lakhal +3 more
wiley +1 more source
On the Metabolism of Malonate and Malonate Decarboxylase Activity in Pseudomonas sp.
Journal of the agricultural chemical society of Japan, 1974 1. Ps. avalis IAM 1177およびPs. fluorescens AT CC 11250を用いて,マロン酸脱炭酸酵素について検討した. 2. 供試菌は培地中に著量の炭酸ガスを放出しながら,マロン酸を炭素源としてよく利用した.菌体にとり込まれたマロン酸の炭素は,他の菌体成分にくらべていちじるしく高く脂質区分に検出された. 3. マロン酸脱炭酸酵素はマロン酸によって誘導されグルコースやリンゴ酸などの炭素源によって強く抑制された.また,メチルマロン酸およびエチルマロン酸にも弱い誘導作用が認められた. 4. Ps. avalisから約16倍に部分精製した酵素標品では,マロン酸のほかにメチルマロン酸が基質となることが認められた. 5.
TAKAMURA, Yoshichika +2 more
openaire +2 more sources
Chemistry – A European Journal, EarlyView.Nitrooxylation—the installation of nitrate esters (–ONO2) has evolved from classical mixed‐acid protocols to catalytic and mechano‐, flow‐, photo‐, and electrochemical strategies. This review delineates ionic and radical manifolds for C–ONO2 bond formation, emphasizing mechanistic control, selected substrate scope, and selectivity.
Jayanta Dey, Dmitry Katayev
wiley +1 more source
Cross‐Dehydrogenative Coupling Reactions With Redox‐Active Guanidine Reagents
Chemistry – A European Journal, EarlyView.ABSTRACT Cross‐dehydrogenative coupling (CDC) reactions are attractive and environmentally friendly ways to form new C‐C and other element‐element bonds. Here, we report the first CDC reactions triggered by a redox‐active guanidine reagent. N‐phenyltetrahydroisoquinoline and derivatives with electron‐donating and withdrawing substituents at the N ...
Petra Walter +2 more
wiley +1 more source
Diastereoselective Synthesis of Highly Substituted Methylene Cyclobutanes by Pd Catalysis
European Journal of Organic Chemistry, EarlyView.A chemo‐ and diastereoselective palladium‐catalyzed intramolecular coupling/cyclization of borylated 1,5‐dienes, readily accessible by allene allylboration, with iodoarenes enables the synthesis of highly substituted methylene cyclobutanes. The method exhibits broad scope, high functional group tolerance, and complete enantiospecificity.
Jose M. Malga +1 more
wiley +1 more source
Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis
European Journal of Organic Chemistry, EarlyView.In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley +1 more source
European Journal of Organic Chemistry, EarlyView.New ylides of two different types were prepared by reaction of 2‐iodosylbenzenesulfonic acid with the corresponding 1,3‐cyclohexanediones under acidic or basic conditions. These compounds have a typical for iodonium ylides structure with the CIC angles 94.18° –97.25° and the IC bond distances between 2.08 and 2.13 Å.
Dmitry M. Noskov +7 more
wiley +1 more source