Results 51 to 60 of about 4,909 (228)
Organocatalytic Asymmetric α-Chlorination of 1,3-Dicarbonyl Compounds Catalyzed by 2-Aminobenzimidazole Derivatives [PDF]
, 2016 Bifunctional chiral 2-aminobenzimidazole derivatives 1 and 2 catalyze the enantioselective stereodivergent α-chlorination of β-ketoesters and 1,3-diketone derivatives with up to 50% ee using N-chlorosuccinimide (NCS) or 2,3,4,4,5,6-hexachloro-2,5 ...
Alonso, Diego A. +2 more
core +3 more sources
Bis(1-adamantyl)(2-morpholinophenyl)phosphine (Mor-DalPhos) [PDF]
, 2014 (ligand employed in transition metal-catalyzed reactions) Alternate Name: di(1-adamantyl)-2-morpholinophenylphosphine. Physical Data: mp 219–224 °C. Solubility: soluble in most polar organic solvents.
Alsabeh +10 more
core +1 more source
SynOpen, 2017 α-Aryl malonate and α-aryl cyano acetate moieties are found in the structures of many bioactive compounds. They are also key intermediates for the synthesis of many compounds such as isoflavonoids.
José F. Cívicos +2 more
doaj +1 more source
Copper-mediated asymmetric transformations [PDF]
, 2017 Copper-catalyzed reactions include the enantioselective conjugate addition and the SN2¢ substitution. We describe the genesis of these reactions, the choice of the primary organometallic reagent, and our studies on finding new Michael acceptors and new ...
Alexakis, Alexandre
core
Diastereoselective conjugate addition of (R)-4-phenyl-2-oxazolidinone to dialkyl alkylidenemalonates [PDF]
, 2014 International audienceThe addition of the potassium salt of (R)-4-phenyl-2-oxazolidinone to dialkyl alkylidenemalonates under various conditions is reported. Very good diastereoselectivities (> 90% de) were obtained in several cases. Conversion of one of
Capra, Julien +4 more
core +2 more sources
Oocyte–cumulus cell interaction: a key factor in early embryo development
Biological Reviews, EarlyView.ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido +2 more
wiley +1 more source
On the Metabolism of Malonate and Malonate Decarboxylase Activity in Pseudomonas sp.
Journal of the agricultural chemical society of Japan, 1974 1. Ps. avalis IAM 1177およびPs. fluorescens AT CC 11250を用いて,マロン酸脱炭酸酵素について検討した. 2. 供試菌は培地中に著量の炭酸ガスを放出しながら,マロン酸を炭素源としてよく利用した.菌体にとり込まれたマロン酸の炭素は,他の菌体成分にくらべていちじるしく高く脂質区分に検出された. 3. マロン酸脱炭酸酵素はマロン酸によって誘導されグルコースやリンゴ酸などの炭素源によって強く抑制された.また,メチルマロン酸およびエチルマロン酸にも弱い誘導作用が認められた. 4. Ps. avalisから約16倍に部分精製した酵素標品では,マロン酸のほかにメチルマロン酸が基質となることが認められた. 5.
TAKAMURA, Yoshichika +2 more
openaire +2 more sources
Pushing the limits of neutral organic electron donors : A tetra(iminophosphorano)-substituted bispyridinylidene [PDF]
, 2015 A new ground-state organic electron donor has been prepared that features four strongly π-donating iminophosphorano substituents on a bispyridinylidene skeleton. Cyclic voltammetry reveals a record redox potential of −1.70 V vs.
Andrieux +36 more
core +1 more source
Chemistry – A European Journal, EarlyView.The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve +4 more
wiley +1 more source
Therapeutic efficacy study of novel 5-FU-loaded PMM 2.1.2-based microspheres on C6 glioma [PDF]
, 2003 The aim of this study was to evaluate the potential of poly(methylidene malonate 2.1.2) as a new drug delivery system to the central nervous system.
A. Vonarbourg +7 more
core +4 more sources