Results 61 to 70 of about 1,395 (183)

Bidirectional Strategy Applied to the Synthesis of Bis(spiroketal)butenolides Using Bismuth(III) Triflate as Catalyst

open access: yesChemistrySelect, Volume 11, Issue 41, 3 November 2026.
The direct synthesis of new trispiro compounds possessing two spiroketalbutenolide subunits only unified by a single carbon atom has been achieved according a tandem bidirectional sequence from a bis(acetylenic) diol and different α‐ketoesters. The reaction catalyzed by bismuth salts delivered as main product (R*,s*,R*) trispiro derivatives which ...
Fabienne Fache   +2 more
wiley   +1 more source

Concurrent Increases in Root Phosphorus Acquisition and Leaf Phosphorus Resorption Underpin Enhanced Phosphorus Economy in Chickpea During Reproductive Development

open access: yesPlant, Cell &Environment, Volume 49, Issue 11, Page 9085-9100, November 2026.
ABSTRACT Phosphorus (P) acquisition and leaf P‐use strategies are critical for reproductive success and productivity, yet, their developmental association during the reproductive phase remains unclear. Five chickpea accessions contrasting in P‐remobilisation efficiency (PRE) were grown in a temperature‐controlled glasshouse under moderate P deficiency.
Xiaolong Feng   +5 more
wiley   +1 more source

Synthesis of Nitrogen‐Containing Heterocyclic Scaffolds and Applications in Scaffold Hopping: Development of an Aripiprazole Analog

open access: yesChemMedChem, Volume 21, Issue 20, 28 October 2026.
A series of 12 novel fused [6,6] saturated and unsaturated nitrogen bicycles is synthesized in three to five steps and expands the CRAFT library's fragment space. A 2,6‐naphthyridin‐3‐ol core replaces the dihydroquinolinone scaffold of aripiprazole, a scaffold‐hopping strategy.
Temitayo Omowumi Alegbejo Price   +12 more
wiley   +1 more source

Flavin Catalysts in Organic Synthesis

open access: yesAngewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley   +2 more sources

Synthesis, Characterization, and In Vitro Evaluation of New Amino‐Alcohol Quinolines as Promising Antimycobacterial Agents

open access: yesChemMedChem, Volume 21, Issue 20, 28 October 2026.
Nontuberculous mycobacteria (NTM) mainly Mycobacterium avium complex (MAC), are emerging pathogens responsible for pulmonary infections. The efficacy of the standard treatment is therefore compromised by the emergence of intrinsic and acquired resistance in MAC.
Elise Si Ahmed Charrier   +6 more
wiley   +1 more source

Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu   +2 more
wiley   +1 more source

Selective N‐Functionalization of Pyrazoles

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.
This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek   +2 more
wiley   +1 more source

The making of Samuel Beckett’s ‘Malone meurt’ / ‘Malone Dies’

open access: yes, 2020
Originally published in French as Malone meurt in 1951 and later translated into English by the author himself, Malone Dies is the second novel of Samuel Beckett's Trilogy. The Making of Samuel Beckett's 'Malone Dies'/'Malone meurt' is a comprehensive reference guide to the history of the text.
Van Hulle, D, Verhulst, P
openaire   +1 more source

Base‐Free Nickel‐Catalyzed Three‐Component Coupling of Aldehydes, Butadiene, and Malonate Derivatives: Toward Sustainable Synthesis of Highly Functionalized Molecules

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.
A nickel‐catalyzed three‐component reaction between arylaldehydes, butadiene, and malonates is developed yielding high functionalized homoallylic alcohols in a single step. No additional base is required and the reaction shows broad substrates compatibility with yields up to 96% and an exclusive selectivity toward the linear E‐isomer.
Anthony Saint Pol   +7 more
wiley   +1 more source

Structural and Spectroscopic Evidence of Hydrogen Bonded Anionic Wires in Protic Ionic Liquids

open access: yesChemPhysChem, Volume 27, Issue 19, 14 October 2026.
Anionic wires of deprotonated carboxylic acids challenge the general wisdom that like charges repel. The hydrogen bond motif observed in the X‐ray structure is even preserved in the liquid state of the material as shown by δ1H NMR spectroscopy. The experimental and theoretical findings provide deep insight into the nature of hydrogen bonding.
Maham Azhar   +5 more
wiley   +1 more source

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