Results 61 to 70 of about 3,999 (147)

Integrated Network Pharmacology, Single‐Cell Transcriptomics Unveil the Mechanistic Role of Morusin in Aortic Dissection

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Aortic dissection is a life‐threatening cardiovascular emergency with limited pharmacological options. This study focuses on elucidating the multi‐target and multi‐pathway mechanisms through which morusin mitigates aortic dissection progression, integrating network pharmacology, single‐cell transcriptomics and experimental validation.
Zhaomeng Wang, Haoran Zhang, Zhanxiong Xie, Yukun Xiang, Yiwen Fu, Zixun Wang, Haiqing Jiao, Nan Lin, Chenguang Niu, Chao Jiang, Lemin Zheng   +10 more
wiley   +1 more source

Confined Acute Type A Aortic Dissection is Characterized by Atherosclerosis

Journal of Cardiac Surgery, Volume 2026, Issue 1, 2026.
Objectives Ascending aortic atherosclerosis and degeneration may influence surgical management and outcome following surgery for acute Type A aortic dissection (ATAAD). The aim of this study was to evaluate the association between histologically confirmed ascending aortic atherosclerosis and postoperative outcome in patients undergoing surgery for ...
Santtu Heikurinen, Ivana Kholova, Timo Paavonen, Ari Mennander, Irfan Ahmad   +4 more
wiley   +1 more source

Frozen Elephant Trunk Technique Contributes to the Prevention of Distal Anastomotic New Entry After Acute Aortic Dissection Repair

Journal of Cardiac Surgery, Volume 2026, Issue 1, 2026.
Objectives The effect of distal anastomotic new entry (DANE) due to suture cutting at the distal anastomosis on the postoperative course remains unknown. We aimed to investigate the impact of DANE on the postoperative course in acute type A aortic dissection (AAAD).
Kayo Sugiyama, Hirotaka Watanuki, Masato Tochii, Hikari Ishiguro, Katsuhiko Matsuyama, Giuseppe Nasso   +5 more
wiley   +1 more source

Complicated type B aortic dissection in a pregnant woman with Marfan syndrome

Journal of Vascular Surgery Cases and Innovative Techniques
Marfan syndrome is a rare inherited connective tissue disorder that can result in significant morbidity and mortality. We report a case of a 29-year-old pregnant woman presenting with an acute type B aortic dissection.
Mohammad M. Zagzoog, MD, Sean A. Crawford, MD, Jean-Michel Davaine, MD, PhD   +2 more
doaj   +1 more source

Open surgical treatment of malperfusion syndrome in Stanford B aortic dissection

Liječnički vjesnik, 2022
INTRODUCTION/OBJECTIVES: Aortic dissection is a life-threatening condition in which a tear occurs in the intima of the aorta. There are two types of aortic dissection, Stanford A and B. Stanford B aortic dissection involves the descending aorta and is treated by lowering blood pressure (BP), with sur-gery being reserved for complications, such as ...
Pinotić, Stjepan, Pinotić, Zlata, Pinotić, Krešimir   +2 more
openaire   +2 more sources

Two Sides of the Same Coin—Mechanistic Insight, Diagnostic Application and Therapeutic Translation of Bacterial and Host‐Derived Extracellular Vesicles

Journal of Extracellular Biology, Volume 4, Issue 11, November 2025.
ABSTRACT Extracellular vesicles (EVs) have gained increasing attention in recent years due to their pivotal role in both health and disease. Emerging from both eukaryotic and prokaryotic cells, EVs serve as essential mediators of intercellular communication, exceeding the simplistic interactions observed with individual molecules. In this comprehensive
Philipp Arnold, Fanni Annamária Boros, Jochen Mattner, Gerald Seidel, Chaofan Liu, Inga Viktoria Hensel, Jan Van Deun, Raphael Schwendner, Janina Müller‐Deile, Nina Sopel, Andreas Ramming, Mario R. Angeli, Simon Rauber, Cláudia Vilhena, Andreas Baur, Stefan Wirtz, Klaus Überla, Heiko Reutter, Linda‐Marie Mulzer, Alina C. Hilger, Friederike Zunke, Wei Xiang, Gregor Fuhrmann, Claudia Günther   +23 more
wiley   +1 more source

The impact of COVID‐19 infection on neonatal birth weight and outcomes

Pregnancy, Volume 1, Issue 6, November 2025.
Abstract Background Since its outbreak in 2019, the novel severe acute respiratory syndrome coronavirus‐2 (COVID‐19) outbreak has had a devastating impact worldwide. Pregnancy has been shown to worsen the clinical outcome in those affected with COVID‐19 infection.
Advaita Punjala‐Patel, Sophia Alvarado, Austin French, Rebekah Lassiter, David Stamilio   +4 more
wiley   +1 more source

Impact of primary entry tear locations on outcomes in acute type A aortic dissection

Scientific Reports
Few studies have explored the impact of different primary entry tear sites in acute type A aortic dissection. We aimed to evaluate the effect of the primary entry tear location on presentation, treatment, and outcome in this condition. We retrospectively
Baku Takahashi, Keiji Kamohara, Hiroyuki Morokuma, Junji Yunoki, Atsushi Kawaguchi   +4 more
doaj   +1 more source

Reverse-Wire TEVAR for Subacute Type B Aortic Dissection with Severe True-Lumen Collapse: A Case Report

Life
Type B aortic dissection (TBAD) requires management tailored to the disease phase and clinical presentation, with the subacute period representing a favorable window for endovascular intervention due to improved procedural safety and remodeling potential.
Andrada Bogdan, Mircea Robu, Elena Nechifor, Aida Badea, Maria Sabina Safta, Alexandru Zaman, Andrada Guță, Bogdan Gaşpar, Gabriel Gorecki, Horațiu Moldovan   +9 more
doaj   +1 more source

Application of the Branch-First Technique in Mesenteric Malperfusion Syndrome Prior to Delayed Open Aortic Repair for Acute Type A Aortic Dissection

Journal of Investigative Surgery
Objective This study evaluated delayed open aortic repair (OAR) following interventional radiology (IR) in patients with acute type A aortic dissection (ATAAD) and mesenteric malperfusion syndrome (MeMPS), and identified clinical predictors of intestinal
Mengmeng Ye, He Sun, Cheng Zeng, Yi Si, Weiguang Wang, Bo Yu, Hongliang Zhao, Kai Ren, Jian Xu, Bo Xu, Shiqiang Yu, Jincheng Liu, Chao Xue, Weixun Duan   +13 more
doaj   +1 more source