Results 91 to 100 of about 940,374 (326)
State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials
Advanced Materials, EarlyView.Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis +6 more
wiley +1 more source
Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction. [PDF]
PLoS ONE, 2018 NLRP12 is a NOD-like receptor that plays multiple roles in both inflammation and tumorigenesis. Despite the importance, little is known about its mechanism of action at the molecular level.
Tengchuan Jin +4 more
doaj +1 more source
PLoS ONE, 2012 Escherichia coli maltose binding protein (MBP) is commonly used to promote the solubility of its fusion partners. To investigate the mechanism of solubility enhancement by MBP, we compared the properties of MBP fusion proteins refolded in vitro with ...
S. Raran-Kurussi, D. Waugh
semanticscholar +1 more source
Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors
Advanced Therapeutics, EarlyView.Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe +4 more
wiley +1 more source
Protein-mediated miRNA detection and siRNA enrichment using p19
BioTechniques, 2010 p19 RNA binding protein from the Carnation Italian ringspot virus (CIRV) is an RNA-silencing suppressor that binds small interfering RNA (siRNA) with high affinity.
Jingmin Jin +3 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 Steroid hormones that serve as vital compounds are necessary for the development and metabolism of a variety of organisms. The neverland (NVD) family genes encode the conserved Rieske-type oxygenases, which are accountable for the dehydrogenation during ...
Shuhong Mao +14 more
doaj +1 more source
BioTechniques, 2022 Antibody (Ab) validation is the procedure in which an Ab is thoroughly assayed for sensitivity and specificity in a given application. Validation of Abs against post-translationally modified (PTM) targets is particularly challenging because it requires ...
Kezzia S Jones +10 more
doaj +1 more source
Kinetics and Thermodynamics of Membrane Protein Folding [PDF]
Biomolecules 2014, 4(1), 354-373, 2014 Understanding protein folding has been one of the great challenges in biochemistry and molecular biophysics. Over the past 50 years, many thermodynamic and kinetic studies have been performed addressing the stability of globular proteins. In comparison, advances in the membrane protein folding field lag far behind. Although membrane proteins constitute
arxiv +1 more source
Advanced Science, Volume 12, Issue 14, April 10, 2025.An engineered Escherichia coli is developed to efficiently produce adipic acid (AA) from cyclohexanol, KA oil (a mixture of cyclohexanol and cyclohexanone), or cyclohexane through a combination of enzyme screening, protein fusion, and genome editing techniques. This approach has achieved the highest recorded productivity for biological AA production to
Fei Wang +6 more
wiley +1 more source
Microbial Cell Factories, 2019 Background The production of therapeutically active single chain variable fragment (scFv) antibody is still challenging in E. coli due to the aggregation propensity of recombinant protein into inclusion bodies (IBs).
Animesh Sarker +2 more
doaj +1 more source