Results 51 to 60 of about 940,374 (326)

Synthesis of fluorinated maltose derivatives for monitoring protein interaction by 19F NMR

open access: yesBeilstein Journal of Organic Chemistry, 2012
A novel reporter system, which is applicable to the 19F NMR investigation of protein interactions, is presented. This approach uses 2-F-labeled maltose as a spy ligand to indirectly probe protein–ligand or protein–protein interactions of proteins fused ...
Michaela Braitsch   +6 more
doaj   +1 more source

An improved fluorescent noncanonical amino acid for measuring conformational distributions using time-resolved transition metal ion FRET

open access: yeseLife, 2021
With the recent explosion in high-resolution protein structures, one of the next frontiers in biology is elucidating the mechanisms by which conformational rearrangements in proteins are regulated to meet the needs of cells under changing conditions ...
William N Zagotta   +9 more
doaj   +1 more source

Binding of anisotropic curvature-inducing proteins onto membrane tubes [PDF]

open access: yesSoft Matter 18, 3384-3394 (2022), 2022
Bin/Amphiphysin/Rvs superfamily proteins and other curvature-inducing proteins have anisotropic shapes and anisotropically bend biomembrane. Here, we report how the anisotropic proteins bind the membrane tube and are orientationally ordered using mean-field theory including an orientation-dependent excluded volume.
arxiv   +1 more source

Two closely related ABC transporters in streptococcus mutans are involved in disaccharide and/or oligosaccharide uptake. [PDF]

open access: yes, 2007
Streptococcus mutans has a large number of transporters apparently involved in the uptake of carbohydrates. At least two of these, the multiple sugar metabolism transporter, MsmEFGK, and the previously uncharacterized MalXFGK, are members of the ATP ...
Homer, Karen A.   +2 more
core   +3 more sources

Curvature sensing of curvature-inducing proteins with internal structure [PDF]

open access: yesPhys. Rev. E 109, 024403 (2024), 2023
Many types of peripheral and transmembrane proteins can sense and generate membrane curvature. Laterally isotropic proteins and crescent proteins with twofold rotational symmetry, such as Bin/Amphiphysin/Rvs superfamily proteins, have been studied theoretically. However, proteins often have an asymmetric structure or a higher rotational symmetry.
arxiv   +1 more source

Maltose-binding protein is a potential carrier for oral immunizations [PDF]

open access: yesVeterinary Immunology and Immunopathology, 2013
Maltose binding protein (MBP) is often fused to a relevant protein to improve its yield and facilitate its purification, but MBP can also enhance the immunogenicity of the fused proteins. Recent data suggest that MBP may potentiate antigen-presenting functions in immunized animals by providing intrinsic maturation stimuli to dendritic cells through ...
Bert Devriendt   +5 more
openaire   +3 more sources

Crystal Structure of Thermotoga maritima α-Glucosidase AglA Defines a New Clan of NAD+-dependent Glycosidases [PDF]

open access: yes, 2003
Glycoside hydrolase family 4 represents an unusual group of glucosidases with a requirement for NAD(+), divalent metal cations, and reducing conditions. The family is also unique in its inclusion of both alpha- and beta-specific enzymes.
Hoffmann, Volker   +4 more
core   +1 more source

Structural basis for the mechanism of ABC transporters. [PDF]

open access: yes, 2015
The ATP-binding cassette (ABC) transporters are primary transporters that couple the energy stored in adenosine triphosphate (ATP) to the movement of molecules across the membrane.
Beis, K
core   +1 more source

Surface analysis of gold nanoparticles functionalized with thiol-modified glucose SAMs for biosensor applications.

open access: yesFrontiers in Chemistry, 2016
In this work, Time of Flight Secondary Ion Mass Spectrometry (ToF-SIMS), Principal Component Analysis (PCA) and X-ray Photoelectron Spectroscopy (XPS) have been used to characterize the surface chemistry of gold substrates before and after ...
Valentina eSpampinato   +6 more
doaj   +1 more source

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