Results 51 to 60 of about 936,446 (303)
Frontiers in Physics, 2016 ATP-binding cassette (ABC) transporters are integral membrane proteins which mediate the exchange of diverse substrates across membranes powered by ATP molecules.
Holger eFlechsig
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In silico evidence that protein unfolding is as a precursor of the protein aggregation [PDF]
ChemPhysChem 2020, 21, 377, 2019 We present a computational study on the folding and aggregation of proteins in aqueous environment, as function of its concentration. We show how the increase of the concentration of individual protein species can induce a partial unfolding of the native conformation without the occurrence of aggregates. A further increment of the protein concentration
arxiv +1 more source
The remarkable solubility-enhancing power of Escherichia coli maltose-binding protein.
Postepy biochemii, 2016 A common problem encountered during the production of recombinant proteins, particularly in bacteria, is their tendency to accumulate in an insoluble and inactive form (i.e., as inclusion bodies).
D. Waugh
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The malQ gene is essential for starch metabolism in Streptococcus mutans
Journal of Oral Microbiology, 2013 Background: The malQ and glgP genes, respectively, annotated as putative 4-α-glucanotransferase and putative glycogen phosphorylase are located with a 29 nucleotide overlap on the Streptococcus mutans genome.
Yutaka Sato +2 more
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Maltose binding protein-fusion enhances the bioactivity of truncated forms of pig myostatin propeptide produced in E. coli. [PDF]
PLoS ONE, 2017 Myostatin (MSTN) is a potent negative regulator of skeletal muscle growth. MSTN propeptide (MSTNpro) inhibits MSTN binding to its receptor through complex formation with MSTN, implying that MSTNpro can be a useful agent to improve skeletal muscle growth ...
Sang Beum Lee +2 more
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Precursor maltose-binding protein is active in binding substrate.
Journal of Biological Chemistry, 1979 Precursor maltose-binding protein synthesized in vitro was shown to be active in binding maltose by affinity chromatography.
Thomas Ferenci, Linda L. Randall
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UV difference spectroscopy of ligand binding to maltose‐binding protein [PDF]
FEBS Letters, 1992 We have used UV absorbance spectroscopy to study the binding of linear and circular maltodextrins to maltose‐binding protein (MBP). Titrations with maltose yield three ??? points in the difference spectrum of MBP, consistent with two protein conformations: ligand‐free and ligand‐bound.
Kalle Gehring +2 more
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Protein quality control in the bacterial periplasm
Microbial Cell Factories, 2004 The proper functioning of extracytoplasmic proteins requires their export to, and productive folding in, the correct cellular compartment. All proteins in Escherichia coli are initially synthesized in the cytoplasm, then follow a pathway that depends ...
Betton Jean-Michel, Miot Marika
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A novel methodology on distributed representations of proteins using their interacting ligands [PDF]
Bioinformatics 2018, 2018 The effective representation of proteins is a crucial task that directly affects the performance of many bioinformatics problems. Related proteins usually bind to similar ligands. Chemical characteristics of ligands are known to capture the functional and mechanistic properties of proteins suggesting that a ligand based approach can be utilized in ...
arxiv +1 more source
Visualizing conformational dynamics of proteins in solution and at the cell membrane
eLife, 2018 Conformational dynamics underlie enzyme function, yet are generally inaccessible via traditional structural approaches. FRET has the potential to measure conformational dynamics in vitro and in intact cells, but technical barriers have thus far limited ...
Sharona E Gordon +2 more
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