Results 101 to 110 of about 323,067 (356)
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
A leucistic female Canis latrans (Carnivora: Canidae) in Costa Rica
Cuadernos de investigación UNED, 2019 Partial depigmentation (leucism) is rare in mammals. We report 17 camera trap records of a single female leucistic coyote (Canis latrans) in Costa Rica between 2014 and 2018.
Stephanny Arroyo Arce +5 more
doaj +1 more source
Comparative histological study of the reinforced area of the saccular membrane in mammals [PDF]
Comparative histological study of reinforced area of saccular membrane in ...
Igarashi, M.
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Knowledge and Management of Aquatic Ecosystems, 1997 De par ses activités diversifiées, l'homme a modifié en permanence la faune mammalienne de France métropolitaine. Responsable de certaines extinctions, il est également à l'origine de réintroductions d'espèces autochtones et d'introductions d'espèces ...
MAURIN H., GAVAZZI E.
doaj +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
The Bowhead Whale, Balaena mysticetus: Its Historic and Current Status [PDF]
, 1995 The bowhead whale, Balaena mysticetus, is currently listed as endangered under the Endangered Species Act of 1973 and as depleted under the Marine Mammal Protection Act of 1972.
Rugh, David J., Shelden, Kim E. W.
core
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source