Results 101 to 110 of about 174,708,283 (296)

Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer

BMC Cancer, 2010
Background The mammalian target of rapamycin (mTOR) plays a key role in cellular growth and homeostasis. The purpose of our present study is to investigate the expression of activated mTOR (p-mTOR) in gastric cancer patients, their prognostic ...
Zhan You-qing, Fang Xin-juan, Cai Mu-yan, Tian Ying, Geng Qi-rong, Xu Da-zhi, Zhou Zhi-wei, Li Wei, Chen Ying-bo, Sun Xiao-wei, Guan Yuan-xiang, Li Yuan-fang, Lin Tong-yu   +12 more
doaj   +1 more source

Supplementary Data from Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway by Nanoparticle Albumin-Bound–Rapamycin and Perifosine Induces Antitumor Activity in Multiple Myeloma

, 2010
Supplementary Data from Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway by Nanoparticle Albumin-Bound–Rapamycin and Perifosine Induces Antitumor Activity in Multiple ...
Loredana Santo (48961), Shweta Kapoor (15042402), Samantha Pozzi (48958), Siddhartha Mukherjee (6088457), Neil Desai (5096627), Shireen Vali (254361), Kishan Patel (1863400), Sonia Vallet (48954), Peter Sportelli (15042399), Diana Cirstea (48960), Gullu Gorgun (832680), Scott Rodig (423356), Teru Hideshima (48951), Kenneth C. Anderson (9242462), Noopur Raje (48953), Hiroshi Ikeda (48952), Giulia Perrone (12524735), Nikhil C. Munshi (11252636)   +17 more
core   +1 more source

Responses to hypoxia via mTOR : role in endothelial cell proliferation and HIF-1[alpha] stabilization [PDF]

, 2005
Ischemic cardiovascular disease and cancer are life-threatening disorders in human mortality. Intensive studies on the etiology of and therapeutics for the diseases are ongoing.
Li, Weimin
core   +1 more source

MicroRNA‐Seq Analysis Reveals a Critical Role for miR‐222 in Bovine Intramuscular Adipogenesis via the DDIT4/mTORC1 Axis

Animal Research and One Health, EarlyView.
Schematic diagram illustrating how miR‐222 promotes bovine intramuscular adipogenesis by targeting DDIT4 to activate the mTORC1 signaling pathway. ABSTRACT Intramuscular fat (IMF) is a key determinant of beef quality, particularly with respect to tenderness, flavor, and juiciness.
Jianbing Tan, Liang Qiu, Zhenghai Zhou, Zhipeng Zhang, Nanfei Wang, Jiangang Hao, Linsen Zan, Wucai Yang   +7 more
wiley   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Huge soft tissue PEComa with aggressive lung and bone metastases

Journal of Cancer Research and Practice, 2017
Perivascular epithelioid cell tumors (PEComas) are uncommon mesenchymal tumors characterized by the presence of both myogenic and melanocytic markers, and huge soft tissue PEComas are even rarer.
Shih-Hao Tang, Yi-Chang Liu, Hui-Hua Hsiao, Shih-Feng Cho, Yu-Fen Tsai, Hui-Ching Wang, Sheng-Fung Lin, Ta-Chih Liu   +7 more
doaj   +1 more source

Supplementary Figure 1 from Targeting Mammalian Target of Rapamycin by Rapamycin Prevents Tumor Progression in an Oral-Specific Chemical Carcinogenesis Model

, 2009
Supplementary Figure 1 from Targeting Mammalian Target of Rapamycin by Rapamycin Prevents Tumor Progression in an Oral-Specific Chemical Carcinogenesis ...
Vyomesh Patel (29261), Alfredo A. Molinolo (8878619), Rakefet Czerninski (15092398), J. Silvio Gutkind (90145), Panomwat Amornphimoltham (14889146)   +4 more
core   +1 more source