Results 41 to 50 of about 369,864 (299)

Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice

open access: yeseLife, 2020
Tissue-resident macrophages in the mammary gland are found in close association with epithelial structures and within the adipose stroma, and are important for mammary gland development and tissue homeostasis.
Ying Wang   +8 more
doaj   +1 more source

Human breast organoid models for lactation research

open access: yesReproduction and Breeding, 2023
The human mammary gland is the major organ involved in lactation. In the mammary gland, alveoli secrete milk and myoepithelial cells contract to propel the milk through branched structures called ducts and eventually to the nipple.
Jenny Lee   +4 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

ADIPOSITY OF THE MAMMARY GLANDS [PDF]

open access: yesJournal of the American Medical Association, 1911
There are no more interesting and few more mysterious quesions in the field of physiologic research than those concerned with the problem of fat metabolism. As a pathologic process, an abnormal fatty condition has been discovered in various organs; one of us (Guthrie) reported a case of necrosis (with fatty change) of the kidney, in the Section on ...
openaire   +2 more sources

Gap Junctions and Wnt Signaling in the Mammary Gland: a Cross-Talk? [PDF]

open access: yes, 2019
Connexins (Cxs), the building blocks of gap junctions (GJs), exhibit spatiotemporal patterns of expression and regulate the development and differentiation of the mammary gland, acting via channel-dependent and channel-independent mechanisms. Impaired Cx
El-Sibai, Mirvat   +4 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

A single-institution retrospective evaluation of noninvasive localization for non-palpable breast microcalcification

open access: yesAsian Journal of Surgery
Technique: From January 1, 2018, to December 31, 2021, we localized the breast microcalcification of 40 patients before the surgical excision. We measured the distance between the nipple and the center of the calcification on the CC view and the ML view,
Yunpeng Li, Min Li, Yueqiu Zhang
doaj   +1 more source

Lactation defect with impaired secretory activation in AEBP1-null mice. [PDF]

open access: yesPLoS ONE, 2011
Adipocyte enhancer binding protein 1 (AEBP1) is a multifunctional protein that negatively regulates the tumor suppressor PTEN and IκBα, the inhibitor of NF-κB, through protein-protein interaction, thereby promoting cell survival and inflammation.
Lei Zhang   +5 more
doaj   +1 more source

A Mammary Organoid Model to Study Branching Morphogenesis

open access: yesFrontiers in Physiology, 2022
Branching morphogenesis is the process that gives rise to branched structures in several organs, such as the lung, the kidney, and the mammary gland. Although morphologically well described, the exact mechanisms driving branch elongation and bifurcation ...
Marika Caruso   +5 more
doaj   +1 more source

Lymph Drainage of the Mammary Glands in Female Cats [PDF]

open access: yes, 2006
The mammary gland is a common site of neoplasms in the female cat. All the malignant tumors metastasize to a lesser or a greater extent through the lymphatic system.
Sautet, Jean, Raharison, Fidiniaina
core   +1 more source

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