Results 41 to 50 of about 142,576 (312)

Immunobiology of the Mammary Gland

Journal of Dairy Science, 1997
The mammary gland is a complex organ that provides neonatal offspring with milk for nourishment and disease resistance. Specific and innate immune factors associated with mammary gland tissues and secretion also play a vital role in protecting the gland from infectious disease.
L M, Sordillo, K, Shafer-Weaver, D, DeRosa   +2 more
openaire   +2 more sources

Identification of long non-coding RNAs in the early growth stage of Holstein mammary gland

The European Zoological Journal, 2020
In Holsteins, emerging evidence suggests that long non-coding RNAs (lncRNAs) are actively involved in the regulation of mammary gland development. However, the lncRNA expression pattern in the early growth stage of Holstein mammary gland remains little ...
K. Du, A.-Y. Ren, M.-C. Cai, G.-Z. Wang, X.-B. Jia, S.-Q. Hu, J. Wang, S.-Y. Chen, S.-J. Lai   +8 more
doaj   +1 more source

Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice

eLife, 2020
Tissue-resident macrophages in the mammary gland are found in close association with epithelial structures and within the adipose stroma, and are important for mammary gland development and tissue homeostasis.
Ying Wang, Thomas S Chaffee, Rebecca S LaRue, Danielle N Huggins, Patrice M Witschen, Ayman M Ibrahim, Andrew C Nelson, Heather L Machado, Kathryn L Schwertfeger   +8 more
doaj   +1 more source

Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland

, 2005
We have developed a mouse model of diet-induced obesity that shows numerous abnormalities relating to mammary gland function. Animals ate 40% more calories when offered a high-fat diet and gained weight at three times the rate of controls. They exhibited
Kelly, Paul A., Flint, David J., Travers, Maureen T., Barber, Michael C., Binart, Nadine, Travers, M., Barber, M.C., Flint, D.J., Kelly, P.A., Binart, N.   +9 more
core   +1 more source

A Mammary Organoid Model to Study Branching Morphogenesis

Frontiers in Physiology, 2022
Branching morphogenesis is the process that gives rise to branched structures in several organs, such as the lung, the kidney, and the mammary gland. Although morphologically well described, the exact mechanisms driving branch elongation and bifurcation ...
Marika Caruso, Sjanie Huang, Larissa Mourao, Larissa Mourao, Colinda L. G. J. Scheele, Colinda L. G. J. Scheele   +5 more
doaj   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Lactation defect with impaired secretory activation in AEBP1-null mice. [PDF]

PLoS ONE, 2011
Adipocyte enhancer binding protein 1 (AEBP1) is a multifunctional protein that negatively regulates the tumor suppressor PTEN and IκBα, the inhibitor of NF-κB, through protein-protein interaction, thereby promoting cell survival and inflammation.
Lei Zhang, Shannon P Reidy, Oleg Bogachev, Brian K Hall, Amin Majdalawieh, Hyo-Sung Ro   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

RNA-Seq Reveals the Expression Profiles of Long Non-Coding RNAs in Lactating Mammary Gland from Two Sheep Breeds with Divergent Milk Phenotype

Animals, 2020
Long non-coding RNAs (lncRNAs) are a kind of non-coding RNA with >200 nucleotides in length. Some lncRNAs have been proven to have clear regulatory functions in many biological processes of mammals.
Zhiyun Hao, Yuzhu Luo, Jiqing Wang, Jiang Hu, Xiu Liu, Shaobin Li, Xiayang Jin, Na Ke, Mengli Zhao, Liyan Hu, Yujie Lu, Xinmiao Wu, Lirong Qiao   +12 more
doaj   +1 more source

ADIPOSITY OF THE MAMMARY GLANDS [PDF]

Journal of the American Medical Association, 1911
There are no more interesting and few more mysterious quesions in the field of physiologic research than those concerned with the problem of fat metabolism. As a pathologic process, an abnormal fatty condition has been discovered in various organs; one of us (Guthrie) reported a case of necrosis (with fatty change) of the kidney, in the Section on ...
openaire   +2 more sources