Results 21 to 30 of about 369,864 (299)

Anti-Collagenase, Anti-Hyaluronidase, Anti-Elastase, and Anti Breast Cancer Potential of Hirsutenone as Natural Compound: In vitro Study, Molecular Docking and Dynamics Simulation Studies [PDF]

Iranian Journal of Chemistry & Chemical Engineering
Many natural medicines derived from Chinese herbs have been discovered recently to have anti-cancer potential both in vitro and in silico. In this work, Hyaluronidase molecule inhibited the enzymes collagenase, elastase, and hyaluronidase.
Zhibing Zhou, Bing Zhou, Yue Gao, Xiaobo Wu, Wensong Wei, Erwei Hu, Shiqing Li   +6 more
doaj   +1 more source

Progesterone promotes immunomodulation and tumor development in the murine mammary gland

Journal for ImmunoTherapy of Cancer, 2021
Background Clinical studies have linked usage of progestins (synthetic progesterone [P4]) to breast cancer risk. However, little is understood regarding the role of native P4, signaling through the progesterone receptor (PR), in breast tumor formation ...
Alfredo A Molinolo, Junping Wei, Xiao-Yi Yang, Gangjun Lei, Zachary C Hartman, Lauryn R Werner, Katelin A Gibson, Merit L Goodman, Dominika E Helm, Katherine R Walter, Sean M Holloran, Gloria M Trinca, Richard C Hastings, Howard H Yang, Rashna Madan, Mary A Markiewicz, Prabhakar Chalise, Margaret L Axelrod, Justin M Balko, Kent W Hunter, Carol A Lange, Christy R Hagan   +21 more
doaj   +1 more source

Long noncoding RNA LINC00511 contributes to breast cancer tumourigenesis and stemness by inducing the miR-185-3p/E2F1/Nanog axis

Journal of Experimental & Clinical Cancer Research, 2018
Background Emerging evidence have illustrated the vital role of long noncoding RNAs (lncRNAs) long intergenic non-protein coding RNA 00511 (LINC00511) on the human cancer progression and tumorigenesis.
Guanming Lu, Yueyong Li, Yanfei Ma, Jinlan Lu, Yongcheng Chen, Qiulan Jiang, Qiang Qin, Lifeng Zhao, Qianfang Huang, Zhizhai Luo, Shiqing Huang, Zhongheng Wei   +11 more
doaj   +1 more source

MiR-382 inhibits proliferation and migration of triple negative breast cancer cell line 4T1 by mediating PGC-1α

Di-san junyi daxue xuebao, 2019
Objective To explore the effect of miR-382 down-regulating PGC-1α on the biological behaviors of triple negative breast cancer 4T1 cells. Methods ① After miR-382 mimics or inhibitory probe anti-miR-382 was transfected into 4T1 cells, the expression level
LEI Youyang, ZHOU Hua, DAI Meng, JIN Xin, MING Jia   +4 more
doaj   +1 more source

LncRNA SNHG6 enhances the radioresistance and promotes the growth of cervical cancer cells by sponging miR-485-3p

Cancer Cell International, 2020
Background Cervical cancer (CC) is the one of most common malignant gynecological tumors, which is characterized with the high mortality and recurrence rate.
Jin Liu, Xiaojiao Liu, Rong Li
doaj   +1 more source

TUBERCULOSIS OF THE MAMMARY GLAND. [PDF]

JAMA: The Journal of the American Medical Association, 1898
Until very recent times tuberculosis of the breast has been considered one of the rarest surgical conditions; this is especially true of primary tuberculosis of this gland. Prior to 1880 we find practically no mention of this condition in surgical treatises save by Astley Cooper and Velpeau.
openaire   +1 more source

Pubertal mammary gland development: Insights from mouse models

, 2006
During puberty the mammary gland develops from a rudimentary tree to a branched epithelial network of ducts which can support alveolar development and subsequent milk production during pregnancy and lactation. This process involves growth, proliferation,
Howlin, Jillian,, Martin, Finian, McBryan, Jean, Lund University.   +3 more
core   +2 more sources

Downregulation of CXXC Finger Protein 4 Leads to a Tamoxifen-resistant Phenotype in Breast Cancer Cells Through Activation of the Wnt/β-catenin Pathway

Translational Oncology, 2020
Tamoxifen is a successful endocrine therapy drug for estrogen receptor–positive (ER+) breast cancer. However, resistance to tamoxifen compromises the efficacy of endocrine treatment.
Yijie Fu, Zhu Wang, Chuanxu Luo, Yu Wang, Yanping Wang, Xiaorong Zhong, Hong Zheng   +6 more
doaj   +1 more source

TUBERCULOSIS OF THE MAMMARY GLAND. [PDF]

JAMA: The Journal of the American Medical Association, 1903
Dr. Scudder, 1 in an exhaustive article on "Tuberculosis of the Mammary Gland," states that an examination of the literature showed only eighty cases reported up to that time, twenty-three of which were rejected on account of imperfect data. This list, however, does not include twelve cases reported by Albert in his work on surgery.
openaire   +1 more source

Pleiotrophin (PTN) expression and function and in the mouse mammary gland and mammary epithelial cells. [PDF]

PLoS ONE, 2012
Expression of the heparin-binding growth factor, pleiotrophin (PTN) in the mammary gland has been reported but its function during mammary gland development is not known. We examined the expression of PTN and its receptor ALK (Anaplastic Lymphoma Kinase)
Sonia M Rosenfield, Emma T Bowden, Shani Cohen-Missner, Krissa A Gibby, Virginie Ory, Ralf T Henke, Anna T Riegel, Anton Wellstein   +7 more
doaj   +1 more source