Results 1 to 10 of about 369,864 (299)

Partial breast reconstruction of 30 cases with peri-mammary artery perforator flaps

BMC Surgery, 2023
Background Volume replacement is one of the vital techniques of oncoplastic surgery (OPS) when applying breast-conserving surgery. The clinical application of peri-mammary artery perforator flaps for this indication is uneven in China.
Meiying Shen, Yuhang Xu, Zongyuan Wu, Jiaming Wang, Huawen Pan, Bo Xu   +5 more
doaj   +1 more source

A Retrospective Analysis of the Effect of Irinotecan-Based Regimens in Patients With Metastatic Breast Cancer Previously Treated With Anthracyclines and Taxanes

Frontiers in Oncology, 2021
BackgroundAt present, patients with metastatic breast cancer (MBC) have few treatment options after receiving anthracyclines and taxanes. Studies have shown that irinotecan has modest systemic activity in some patients previously treated with ...
Jiaojiao Suo, Xiaorong Zhong, Xiaorong Zhong, Ping He, Ping He, Hong Zheng, Hong Zheng, Tinglun Tian, Tinglun Tian, Xi Yan, Xi Yan, Ting Luo, Ting Luo   +12 more
doaj   +1 more source

Cost-effectiveness of different surgical treatment approaches for early breast cancer: a retrospective matched cohort study from China

BMC Cancer, 2021
Background Both breast-conserving surgery and breast reconstruction surgery are less popular in China, although they can improve patients’ quality of life. The main reason comes from the economy.
Qing Yang, Xiaorong Zhong, Wei Zhang, Ting Luo, Ping He, Hong Zheng   +5 more
doaj   +1 more source

Transcriptome profiling of the nonlactating mammary glands of dairy goats reveals the molecular genetic mechanism of mammary cell remodeling

Journal of Dairy Science, 2022
: The mammary gland redevelops to the prepregnancy state during involution, which shows the mammary cells have the characteristics of remodeling. The rapidity and degree of mammary gland involution vary across species (e.g., between model organism mice ...
Rong Xuan, Tianle Chao, Xiaodong Zhao, Aili Wang, Yunpeng Chu, Qing Li, Yilin Zhao, Zhibin Ji, Jianmin Wang   +8 more
doaj   +1 more source

The Diagnostic Value of Bedside Echocardiography and Lower Extremity Blood Vessels in Acute Pulmonary Embolism

Stem Cells International, 2022
Objective. The study aimed to evaluate the value of bedside echocardiography (TTE) and lower extremity blood vessels in diagnosis and prognosis of acute pulmonary embolism (APE). Methods.
Xinxin Xu, Jing Yuan, Xiaojie Pan, Guibin Du, Jiahui Zhang   +4 more
doaj   +1 more source

A review of current progress in triple-negative breast cancer therapy

Open Medicine, 2020
Triple-negative breast cancer (TNBC) is a particularly aggressive subtype known for its extremely high drug resistance, progression, poor prognosis, and lack of clear therapeutic targets. Researchers are aiming to advance TNBC treatment worldwide. In the
Shen Meiying, Pan Huawen, Chen Yuxia, Xu Yu Hang, Yang Weixiong, Wu Zhaojun   +5 more
doaj   +1 more source

Expression analysis of rare cellular subsets: direct RT-PCR on limited cell numbers obtained by FACS or soft agar assays

BioTechniques, 2013
Since tissues and tumors are heterogenous populations containing different cell types, their transcriptomes are blends of multiple mRNA expression profiles.
Victor Ho, Shi Yun Yeo, Kamini Kunasegaran, Duvini De Silva, Gerard A. Tarulli, P. Mathijs Voorhoeve, Alexandra M. Pietersen   +6 more
doaj   +1 more source

Single-Cell Transcriptomics Identifies Heterogeneity of Mouse Mammary Gland Fibroblasts With Distinct Functions, Estrogen Responses, Differentiation Processes, and Crosstalks With Epithelium

Frontiers in Cell and Developmental Biology, 2022
Fibroblasts have been shown to be one of the essential players for mammary gland organization. Here, we identify two major types of mouse mammary gland fibroblasts through single-cell RNA sequencing analysis: Dpp4+ fibroblasts and Dpp4- fibroblasts. Each
Ryohei Yoshitake, Gregory Chang, Kohei Saeki, Kohei Saeki, Desiree Ha, Xiwei Wu, Jinhui Wang, Shiuan Chen   +7 more
doaj   +1 more source

Investigating the effect of positional variation on mid-lactation mammary gland transcriptomics in mice fed either a low-fat or high-fat diet.

PLoS ONE, 2021
Little attention has been given to the effect of positional variation of gene expression in the mammary gland. However, more research is shedding light regarding the physiological differences that mammary gland location can have on the murine mammary ...
Adrienne A Cheng, Wenli Li, Laura L Hernandez   +2 more
doaj   +1 more source

A Robust Mammary Organoid System to Model Lactation and Involution-like Processes

Bio-Protocol, 2021
The mammary gland is a highly dynamic tissue that changes throughout reproductive life, including growth during puberty and repetitive cycles of pregnancy and involution. Mammary gland tumors represent the most common cancer diagnosed in women worldwide.
Elsa Charifou, Jakub Sumbal, Zuzana Koledova, Han Li, Aurelie Chiche   +4 more
doaj   +1 more source