Results 11 to 20 of about 124,049 (166)

Single-Cell Transcriptomics Identifies Heterogeneity of Mouse Mammary Gland Fibroblasts With Distinct Functions, Estrogen Responses, Differentiation Processes, and Crosstalks With Epithelium

Frontiers in Cell and Developmental Biology, 2022
Fibroblasts have been shown to be one of the essential players for mammary gland organization. Here, we identify two major types of mouse mammary gland fibroblasts through single-cell RNA sequencing analysis: Dpp4+ fibroblasts and Dpp4- fibroblasts. Each
Ryohei Yoshitake, Gregory Chang, Kohei Saeki, Kohei Saeki, Desiree Ha, Xiwei Wu, Jinhui Wang, Shiuan Chen   +7 more
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Mammary Gland Neoplasia [PDF]

Environmental Health Perspectives, 1996
Determining how findings of chemically induced carcinogenic effects in rodents can properly be interpreted for human health poses a continuing challenge to the risk assessment community. One approach begins by comparing and contrasting carcinogenic process in rodents and humans, identifying biologically significant similarities and differences and gaps
D A, Neumann, T M, Crisp, S S, Olin
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Expression analysis of rare cellular subsets: direct RT-PCR on limited cell numbers obtained by FACS or soft agar assays

BioTechniques, 2013
Since tissues and tumors are heterogenous populations containing different cell types, their transcriptomes are blends of multiple mRNA expression profiles.
Victor Ho, Shi Yun Yeo, Kamini Kunasegaran, Duvini De Silva, Gerard A. Tarulli, P. Mathijs Voorhoeve, Alexandra M. Pietersen   +6 more
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A Robust Mammary Organoid System to Model Lactation and Involution-like Processes

Bio-Protocol, 2021
The mammary gland is a highly dynamic tissue that changes throughout reproductive life, including growth during puberty and repetitive cycles of pregnancy and involution. Mammary gland tumors represent the most common cancer diagnosed in women worldwide.
Elsa Charifou, Jakub Sumbal, Zuzana Koledova, Han Li, Aurelie Chiche   +4 more
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Investigating the effect of positional variation on mid-lactation mammary gland transcriptomics in mice fed either a low-fat or high-fat diet.

PLoS ONE, 2021
Little attention has been given to the effect of positional variation of gene expression in the mammary gland. However, more research is shedding light regarding the physiological differences that mammary gland location can have on the murine mammary ...
Adrienne A Cheng, Wenli Li, Laura L Hernandez   +2 more
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Progesterone promotes immunomodulation and tumor development in the murine mammary gland

Journal for ImmunoTherapy of Cancer, 2021
Background Clinical studies have linked usage of progestins (synthetic progesterone [P4]) to breast cancer risk. However, little is understood regarding the role of native P4, signaling through the progesterone receptor (PR), in breast tumor formation ...
Alfredo A Molinolo, Junping Wei, Xiao-Yi Yang, Gangjun Lei, Zachary C Hartman, Lauryn R Werner, Katelin A Gibson, Merit L Goodman, Dominika E Helm, Katherine R Walter, Sean M Holloran, Gloria M Trinca, Richard C Hastings, Howard H Yang, Rashna Madan, Mary A Markiewicz, Prabhakar Chalise, Margaret L Axelrod, Justin M Balko, Kent W Hunter, Carol A Lange, Christy R Hagan   +21 more
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Anti-Collagenase, Anti-Hyaluronidase, Anti-Elastase, and Anti Breast Cancer Potential of Hirsutenone as Natural Compound: In vitro Study, Molecular Docking and Dynamics Simulation Studies [PDF]

Iranian Journal of Chemistry & Chemical Engineering
Many natural medicines derived from Chinese herbs have been discovered recently to have anti-cancer potential both in vitro and in silico. In this work, Hyaluronidase molecule inhibited the enzymes collagenase, elastase, and hyaluronidase.
Zhibing Zhou, Bing Zhou, Yue Gao, Xiaobo Wu, Wensong Wei, Erwei Hu, Shiqing Li   +6 more
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TUBERCULOSIS OF THE MAMMARY GLAND. [PDF]

JAMA: The Journal of the American Medical Association, 1898
Until very recent times tuberculosis of the breast has been considered one of the rarest surgical conditions; this is especially true of primary tuberculosis of this gland. Prior to 1880 we find practically no mention of this condition in surgical treatises save by Astley Cooper and Velpeau.
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Long noncoding RNA LINC00511 contributes to breast cancer tumourigenesis and stemness by inducing the miR-185-3p/E2F1/Nanog axis

Journal of Experimental & Clinical Cancer Research, 2018
Background Emerging evidence have illustrated the vital role of long noncoding RNAs (lncRNAs) long intergenic non-protein coding RNA 00511 (LINC00511) on the human cancer progression and tumorigenesis.
Guanming Lu, Yueyong Li, Yanfei Ma, Jinlan Lu, Yongcheng Chen, Qiulan Jiang, Qiang Qin, Lifeng Zhao, Qianfang Huang, Zhizhai Luo, Shiqing Huang, Zhongheng Wei   +11 more
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LncRNA SNHG6 enhances the radioresistance and promotes the growth of cervical cancer cells by sponging miR-485-3p

Cancer Cell International, 2020
Background Cervical cancer (CC) is the one of most common malignant gynecological tumors, which is characterized with the high mortality and recurrence rate.
Jin Liu, Xiaojiao Liu, Rong Li
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