Results 11 to 20 of about 369,864 (299)
The Mammary Gland Vasculature Revisited [PDF]
Journal of Mammary Gland Biology and Neoplasia, 2010 Concomitant with the extensive growth and differentiation of the mammary epithelium during pregnancy and lactation, and epithelial involution after weaning, the vasculature of the mammary gland undergoes repeated cycles of expansion and regression.
Andres, Anne Catherine +1 more
core +6 more sources
Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3 [PDF]
, 2004 INTRODUCTION: Involution of the mammary gland is a complex process of controlled apoptosis and tissue remodelling. The aim of the project was to identify genes that are specifically involved in this process.
Duffy, M.A. +9 more
core +8 more sources
Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland [PDF]
, 2005 We have developed a mouse model of diet-induced obesity that shows numerous abnormalities relating to mammary gland function. Animals ate 40% more calories when offered a high-fat diet and gained weight at three times the rate of controls. They exhibited
Kelly, Paul A. +9 more
core +4 more sources
ELF5-Mediated Enhancer-Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland. [PDF]
Adv Sci (Weinh)In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Wu X +11 more
europepmc +2 more sources
The Mammary Glands of Macaques [PDF]
Toxicologic Pathology, 2008 This review describes the normal biology and physiology of the mammary gland in macaques, including the typical histologic appearance across the life span (development, reproductive maturity, lactation, and senescence). The molecular events regulating breast morphogenesis are described, as well as systemic and local hormonal regulators of mammary gland
J Mark, Cline, Charles E, Wood
openaire +2 more sources
Development of the mammary gland [PDF]
Reproduction, 1982 Introduction The first obvious statement is that the mammary gland is an intriguing structure, and that its development is one of the most fascinating aspects. During the lifetime of the animal the mammary gland probably undergoes more and greater changes in size, structure, composition and activity than any ...
C H, Knight, M, Peaker
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Mammary gland development [PDF]
WIREs Developmental Biology, 2012 Abstract The mammary gland develops through several distinct stages. The first transpires in the embryo as the ectoderm forms a mammary line that resolves into placodes. Regulated by epithelial–mesenchymal interactions, the placodes descend into the underlying mesenchyme and produce the rudimentary ductal ...
Hector, Macias, Lindsay, Hinck
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Environmental Health Perspectives, 1996 Determining how findings of chemically induced carcinogenic effects in rodents can properly be interpreted for human health poses a continuing challenge to the risk assessment community. One approach begins by comparing and contrasting carcinogenic process in rodents and humans, identifying biologically significant similarities and differences and gaps
D A, Neumann, T M, Crisp, S S, Olin
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ß1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli [PDF]
, 2005 Integrins are cell adhesion receptors which mediate interactions between the extracellular matrix and the actin cytoskeleton. They are heterodimers composed of α and β subunits. As adhesion receptors, integrins are important for cell-cell and cell-matrix
Li, Na
core +1 more source
Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland [PDF]
, 2005 We have demonstrated that insulin-like growth factor binding protein-5 (IGFBP-5) production by mammary epithelial cells increases dramatically during forced involution of the mammary gland in rats, mice and pigs.
Beattie, J +19 more
core +1 more source