Results 61 to 70 of about 733,542 (207)

Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

Nature Cell Biology, 2014
We have previously demonstrated that Stat3 regulates lysosomal-mediated programmed cell death (LM-PCD) during mouse mammary gland involution in vivo. However, the mechanism that controls the release of lysosomal cathepsins to initiate cell death in this ...
T. Sargeant, B. Lloyd-Lewis, H. Resemann, A. Ramos-Montoya, J. Skepper, C. Watson   +5 more
semanticscholar   +1 more source

Effect of Different Breast Densities and Average Glandular Dose on Contrast to Noise Ratios in Full-Field Digital Mammography: Simulation and Phantom Study

Radiology Research and Practice, 2018
We aimed to investigate the effects of mammary gland density and average glandular dose (AGD) on contrast-to-noise ratio (CNR) of breast-equivalent phantoms with different mammary gland/fat tissue ratios. Full-field digital-mammography breast X-rays were
Noriko Nakamura, Yuka Okafuji, Saori Adachi, Kana Takahashi, Takashi Nakakuma, Sohichirou Ueno   +5 more
doaj   +1 more source

Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool

Stem Cell Reports, 2019
Summary: DACH1 abundance is reduced in human malignancies, including breast cancer. Herein DACH1 was detected among multipotent fetal mammary stem cells in the embryo, among mixed lineage precursors, and in adult basal cells and (ERα+) luminal ...
Xuanmao Jiao, Zhiping Li, Min Wang, Sanjay Katiyar, Gabriele Di Sante, Mehdi Farshchian, Andrew P. South, Cinzia Cocola, Daniele Colombo, Rolland Reinbold, Ileana Zucchi, Kongming Wu, Ira Tabas, Benjamin T. Spike, Richard G. Pestell   +14 more
doaj   +1 more source

Mammary gland tumors in a male Cocker Spaniel

Acta Veterinaria Scandinavica, 2017
Background Mammary gland tumors are the most common tumors in sexually intact female dogs; however, they are rare in male dogs. This study was conducted to investigate the relationship between sexual hormones and mammary gland tumors in a male dog.
Soon-Chan Kwon, Dae-Young Yoo, Minho Ko, Kwon-Young Lee, Ho-Hyun Kwak, In-Chul Park, In-Koo Hwang, Jung-Hoon Choi, Jin-Young Chung   +8 more
doaj   +1 more source

Transcriptional profiling of mammary gland in Holstein cows with extremely different milk protein and fat percentage using RNA sequencing

BMC Genomics, 2014
BackgroundRecently, RNA sequencing (RNA-seq) has rapidly emerged as a major transcriptome profiling system. Elucidation of the bovine mammary gland transcriptome by RNA-seq is essential for identifying candidate genes that contribute to milk composition ...
X. Cui, Yali Hou, Shaohua Yang, Yan Xie, Shengli Zhang, Y. Zhang, Qin Zhang, Xuemei Lu, G. Liu, D. Sun   +9 more
semanticscholar   +1 more source

Quantitative Assessment of Mammary Gland Density in Rodents Using Digital Image Analysis

Biological Procedures Online, 2011
Background Rodent models have been used extensively to study mammary gland development and for studies of toxicology and carcinogenesis. Mammary gland gross morphology can visualized via the excision of intact mammary gland chains following fixation and ...
Thompson Henry J, McGinley John N
doaj   +1 more source

mammary gland

Citation: 'mammary gland' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10916 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
Suzanne E. Fenton, Schantel Hayes Bouknight   +1 more
openaire   +2 more sources

A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis

Genes & Development, 2014
In this study, Chen et al. discover that the Hippo pathway is functionally dispensable in virgin mammary glands but specifically required during pregnancy. YAP hyperactivation in mammary epithelia leads to defects in terminal differentiation. Loss of YAP
Qian Chen, Nailing Zhang, R. Gray, Huili Li, A. Ewald, C. Zahnow, D. Pan   +6 more
semanticscholar   +1 more source

Comparison of mouse mammary gland imaging techniques and applications: Reflectance confocal microscopy, GFP Imaging, and ultrasound

BMC Cancer, 2008
Background Genetically engineered mouse models of mammary gland cancer enable the in vivo study of molecular mechanisms and signaling during development and cancer pathophysiology.
Cotarla Ion, Parrish Angela R, Tilli Maddalena T, Jones Laundette P, Johnson Michael D, Furth Priscilla A   +5 more
doaj   +1 more source

DEK promotes mammary hyperplasia and is associated with H3K27me3 epigenetic modifications

Life Science Alliance
The Dek histone chaperone promotes mammary gland development through the regulation of proliferation-driving cell cycle genes and deposition of H3K27me3 epigenetic marks. The DEK chromatin remodeling protein has oncogenic functions in breast cancers, but
Megan E Johnstone, Ashley L Leck, Taylor E Lange, Katherine E Wilcher, Miranda S Shephard, Aditi Paranjpe, Sophia Schutte, Susanne I Wells, Ferdinand Kappes, Nathan Salomonis, Lisa M Privette Vinnedge   +10 more
doaj   +1 more source