Results 141 to 150 of about 31,467 (302)
Veterinary Record, EarlyView.Abstract Background Hepatocellular carcinoma (HCC) is the most common canine hepatobiliary tumour. This study aimed to determine which criteria influenced outcome of HCC in a modern population of dogs across eight institutions. Methods The medical records of 106 dogs with HCC were retrospectively reviewed.
Emily A. Janik +2 more
wiley +1 more source
Wildlife Biology, EarlyView.After decades of dramatic reductions in their populations, Italian wolves have begun recolonizing parts of their historic range. This growth in populations can lead to potential conflicts with human activities, which remain the main cause of wolf mortality.
Ilaria Troisio +8 more
wiley +1 more source
On the structure of the mammary gland in the cetacea, with observations on the mechanism of the mouth and soft palate, as applied by the young animal in sucking [PDF]
The Dublin Journal of Medical and Chemical Sciencen ...
openaire +2 more sources
FELINE MAMMARY HYPERTROPHY/FIBROADENOMA COMPLEX: A RETROSPECTIVE STUDY OF TWENTY-FIVE CASES
, 2012 "Feline mammary hyperplasia is a benign and progesterone responsive. condition. Twenty-five cases of mammary fibroepithelial hyperplasia spontaneous (19). or after treatment (6) with progestin are described: 1 with pyometra, 2 were sisters and.
LEDDA, Sergio +5 more
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A case of canine urothelial carcinoma of the urinary bladder with skull and skeletal metastases
Australian Veterinary Journal, EarlyView.Canine urinary bladder neoplasia is uncommon, representing less than 1% of canine neoplasms. Amongst cases of urinary bladder neoplasia in dogs, primary urothelial carcinoma is the most frequent. Urothelial carcinomas are malignant invasive tumours which tend to be slow growing and metastasise late.
A Teh, T Sima, E Shinozaki, R Malik
wiley +1 more source
Targeting hexokinase 2 to induce breast cancer cell senescence
British Journal of Pharmacology, EarlyView.Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof +8 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and purpose Nano‐formulated chemotherapeutics prolong systemic availability of drugs and can reduce systemic toxicity, but their accumulation in solid tumours is often limited and unpredictable. Broadly applicable strategies to selectively enhance tumour delivery are lacking.
Annabel Kitowski +13 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
Cell Proliferation, EarlyView.Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li +6 more
wiley +1 more source
PiRNAs, a specialized subclass of ncRNAs characterized by their 26–31 nucleotides (nt) length, function through specific interactions with PIWI proteins to form dynamic regulatory complexes that modulate gene expression. As a significant constituent of ncRNAs, piRNAs exhibit distinctive biogenesis mechanisms and regulatory features that underscore ...
Wenjing Yu +4 more
openaire +1 more source