Results 151 to 160 of about 71,975 (282)

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Beyond the chaos: How architecture structures tumour biology

The FEBS Journal, EarlyView.
Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner, Catrin Lutz, Stefan Prekovic, Hendrik A. Messal   +3 more
wiley   +1 more source

Maternal Obesity and MicroRNAs in Breast Milk: Implications for Infant Developmental Programming

Obesity Reviews, EarlyView.
ABSTRACT This review explores the relationship between maternal obesity and alterations in the expression of microRNAs (miRNAs) in breast milk, highlighting how these changes may influence the developmental programming of the infant. Evidence suggests that maternal obesity can affect the bioactive composition of breast milk, including miRNA profiles ...
Gyslane M. Santos, Fabíola Isabel Suano de Souza, Luciana P. Pisani   +2 more
wiley   +1 more source

Polyethylene Terephthalate Micro and Nanoplastics Induce Oxidative and Endoplasmic Reticulum Stress, Compromising Intestinal Epithelial Integrity and Viability

Allergy, EarlyView.
Sena Ardicli, Huseyn Babayev, Lihong Chang, Ozge Ardicli, Can Zeyneloglu, Yagiz Pat, Duygu Yazici, Xiaoqing Liu, Ezgi Irem Bektas, Carina Beha, Halil I. Akyildiz, Nazrin B. Mammadova, Muhammed Emin Sari, Beate Rückert, Raja Dhir, Ismail Ogulur, Kari C. Nadeau, Mubeccel Akdis, Cezmi A. Akdis   +18 more
wiley   +1 more source

Secretory Carcinoma Mimicking a Mucocele: Case Report and Literature Update

Oral Surgery, EarlyView.
ABSTRACT Aim Secretory carcinoma (SC), also known as mammary analogue secretory carcinoma, is a rare malignant neoplasm of the salivary glands, named for its histological and molecular resemblance to mammary secretory carcinoma. The aim of this study is to present a new case of SC occurring in the lower lip, initially diagnosed as a mucocele, and to ...
Débora Frota Colares, André Luis Alves Borges, Leonardo Magalhães Carlan, Adriano Rocha Germano, Antônio de Lisboa Lopes Costa, Hébel Cavalcanti Galvão   +5 more
wiley   +1 more source

Epidemiology of Four Major Canine Tumours in the UK: Insights From a National Pathology Registry With Comparative Oncology Perspectives

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Pet dogs with naturally occurring cancers provide valuable models for comparative oncology and pathology tumour registries offer a powerful resource for onco‐epidemiological research. Here, we analysed the Small Animal Veterinary Surveillance Network (SAVSNET) pathology‐based tumour registry (PTR), one of the largest veterinary tumour ...
José Rodríguez, Antonio Espinosa de los Monteros, Ángelo Santana, P. J. Noble, Alan D. Radford, Francesco Cian, Annika Herrmann, Jenny S. McKay, Matthew Jones, David R. Killick   +9 more
wiley   +1 more source

Estrogen Signaling During Abrupt Involution and Long-Term Metabolic Signature Similar to Estrogen Receptor-Negative Breast Cancer. [PDF]

Int J Mol Sci
Ormiston K, Shinde N, Sarathy G, Zhang A, Bauer M, Shukla RK, Alsammerai S, Gupta A, Bennouna D, Wesolowski J, Zhang X, Kopec RE, Shankar E, Stanford KI, Ganju RK, Majumder S, Ramaswamy B, Stover DG.   +17 more
europepmc   +1 more source

Cytologic Grading of Canine Mammary Tumors by Robinson's System Adapted to Romanowsky‐Type Rapid Staining: Prognostic Implications

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background Mammary neoplasms are a major concern in intact female dogs, and cytologic examination is routinely used for initial screening. Although the adaptation of Robinson's cytologic grading system to canine species has been scarcely explored, it shows prognostic potential, particularly when correlated with other clinical and pathologic ...
Kaian F. Cavalcante, Francisco E. P. Cavalcante, Isabela R. B. Nascimento, Lúcia D. M. Silva, Augusto M. R. Faustino, Breno Q. Pinheiro, Isaac N. G. Silva   +6 more
wiley   +1 more source

Obesity and breast density enhance immune exclusion in the primary tumor microenvironment and promote breast cancer metastasis. [PDF]

Oncogene
Williams AE, Hoffmann EJ, Inman DR, Gari MK, Zhou C, Burkel BM, Haidar N, Pan Y, Halambeck M, Moore BN, Wisinski KB, McGregor SM, Kerr SC, Arendt LM, Ponik SM.   +14 more
europepmc   +1 more source

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

Experimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento, Louisa Tichy, Traci L. Parry   +2 more
wiley   +1 more source