Results 131 to 140 of about 196,671 (187)

AKT, ATR, and Notch Inhibitors Radiosensitize a Preclinical Model of Adenoid Cystic Carcinoma

Head &Neck, Volume 48, Issue 9, Page 2364-2376, September 2026.
ABSTRACT Background Adenoid Cystic Carcinoma (ACC) is a rare and lethal type of head and neck cancer. Standard therapy involves surgery followed by radiation therapy. The majority of ACC has MYB overexpression and MYB‐NFIB gene fusions, while Notch mutations are associated with aggressive behavior.
Shivani Thoidingjam, Sushmitha Sriramulu, Asya Haider Muratoglu, Stephen Brown, Oudai Hassan, Benjamin Movsas, Haythem Ali, Steven Chang, Patrick Ha, Farzan Siddiqui, Shyam Nyati   +10 more
wiley   +1 more source

Genistein Supplementation Affects Mineral Homeostasis in Rats with Mammary Cancer. [PDF]

Foods
Skrajnowska D, Szterk A, Ofiara K, Kowalczyk P, Strus B, Bobrowska-Korczak B.   +5 more
europepmc   +1 more source

MUC1 as a Survival Effector of Radiotherapy‐Induced Epithelial Hybrid States in Basal‐Like Breast Cancer

International Journal of Cancer, Volume 159, Issue 5, Page 1296-1310, 1 September 2026.
Basal‐like breast cancer (BLBC) is aggressive and often exhibits inherent or acquired resistance to radiotherapy (RT), a primary treatment option. RT resistance is underpinned by molecular alterations, many of which are poorly understood. Here, RT‐induced transcriptomic changes were analyzed using bulk and spatial sequencing in a BLBC mouse model and ...
Garyfallia Pantelaiou‐Prokaki, Husam Bamahmoud, Nadine S. Georges, Shaishavi Jansari, Annika Jung, Daniela Grimm, Evangelos Prokakis, Fabian Alexander Gayer, Maryam Deldar, Christian Dullin, Julia Gallwas, Florian Wegwitz, Frauke Alves   +12 more
wiley   +1 more source

Impact of combined unilateral mastectomy and ovariohysterectomy on acute phase response and wound healing in dogs with mammary gland tumors. [PDF]

BMC Vet Res
Wongbandue G, Prompiram P, Chandrasakha P, Prapaiwan N.   +3 more
europepmc   +1 more source

Head and Neck Metastases From Infraclavicular Primary Tumors: Analysis of 136 Cases

The Laryngoscope, Volume 136, Issue 9, Page 3791-3796, September 2026.
ABSTRACT Objective Distant metastases in the head and neck region are rare, often posing challenges for ENT specialists and being of crucial importance in the management of infraclavicular primary tumors. Methods The case series presented here aims to outline the relevant aetiologies and clinical presentation in the head and neck region.
Achim M. Franzen, André Buchali, Carolin Quadt, Annekatrin Coordes   +3 more
wiley   +1 more source

Therapeutic effects of cold plasma-activated water on MCF7 breast cancer tumors in a mouse model. [PDF]

BMC Pharmacol Toxicol
Abd El-Reda G, Mahmoud MAM, Ali FAZ, Abdel-Maksoud FM, Zahran AM, El-Hossary FM.   +5 more
europepmc   +1 more source

Integrated Single‐Cell RNA Sequencing and Untargeted Metabolomics Reveals β‐Elemene's Immune and Metabolic Modulation in Triple‐Negative Breast Cancer

MedComm – Oncology, Volume 5, Issue 3, September 2026.
In a 4T1 TNBC model, β‐elemene suppressed tumor growth and pulmonary metastasis. scRNA‐seq showed it remodeled the tumor microenvironment by reducing cancer‐associated fibroblasts, enhancing antigen presentation, and inhibiting pro‐tumorigenic ECM remodeling. Metabolomics revealed prostaglandin downregulation.
Zhiqiang Luo, Guohua Yu, Huixia Fan, Ruofan Guo, Jingqi Zheng, Chen Wang, Ruyi Jin, Junhui Zhou, Jian Yang   +8 more
wiley   +1 more source

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway. [PDF]

Oncol Rep
Feng H, He L, Umar T, Wang H, Gao Y, Chen G, Sun P, Yin L, Zhao W, Lu H, Deng G, Qiu C.   +11 more
europepmc   +1 more source

Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
wiley   +1 more source