Results 1 to 10 of about 20,210 (217)

Association of pulmonary lymphocytes with radiation-induced lung disease in a mouse model [PDF]

Radiation Oncology
Background Specific congenic mice derived from inbred C3H/HeJ mice, which present early onset pneumonitis, and C57BL/6J mice manifesting later onset pneumonitis with pulmonary fibrosis, vary in time to respiratory distress from these responses following ...
Laetitia Sabatier, Aimée-Lee Luco, Mitchell Wiebe, Christina K. Haston   +3 more
doaj   +2 more sources

A lung cancer mouse model system based on an inbred C3H strain: Ultrasound imaging, pathological analysis, and proteomic biomarker identification [PDF]

Veterinary World
Background and Aim: Lung cancer remains a leading cause of global mortality, necessitating robust animal models for research into its mechanisms and therapeutic options.
Ulayatul Kustiati, Wahyu Tri Widayati, Dwi Liliek Kusindarta, Dwi Aris Agung Nugrahaningsih, Dinda Aliffia, Wilda Bunga Tina Sanjaya, Hevi Wihadmadyatami   +6 more
doaj   +2 more sources

Caracterização biológica de clones das cepas Y, CL e MR de Trypanosoma cruzi em camundongos C3H isogênicos Biological characterization of Trypanosoma cruzi clones from Y, CL and MR strains in C3H inbred mice

Memorias do Instituto Oswaldo Cruz, 1988
Dez clones isolados das cepas Y, CL e MR foram caracterizados segundo infectividade das culturas, curvas de parasitemia, polimorfismo e mortalidade em camundongos C3H isogênicos.
S. Marques de Araújo, E. Chiari
doaj   +2 more sources

Proteome analysis of high affinity mouse saliva proteins to hydroxyapatite

Heliyon, 2022
Caries sensitivity varies between the two strains of inbred mice, BALB/cA has high sensitivity and C3H/HeN has low sensitivity. One potential reason seems to be a difference in pellicle-forming saliva protein composition.
Keijiro Ohshima, Tomoko Ohshima, Karen Meyer, Eisuke Takai, Shunsuke Yoshizawa, Kentaro Shiraki, Nobuko Maeda   +6 more
doaj   +1 more source

Inter-Strain Epigenomic Profiling Reveals a Candidate IAP Master Copy in C3H Mice

Viruses, 2020
Insertions of endogenous retroviruses cause a significant fraction of mutations in inbred mice but not all strains are equally susceptible. Notably, most new Intracisternal A particle (IAP) ERV mutagenic insertions have occurred in C3H mice. We show here
Rita Rebollo, Mariana Galvão-Ferrarini, Liane Gagnier, Ying Zhang, Ardian Ferraj, Christine R. Beck, Matthew C. Lorincz, Dixie L. Mager   +7 more
doaj   +1 more source

Compensatory role of C3 convertase on the strain difference for C3 protein expression in FVB/N, C3H/HeN and C57BL/6N mice

Laboratory Animal Research, 2020
To investigate the role of complement C3 (C3) convertase on the strain difference for C3 protein expression in three inbred mice strains, we compared the levels of C2, C3 and C4 mRNA, as well as C3 protein and C3 convertase activity in the serum and ...
Ji Won Park, Ji Eun Kim, Mi Ju Kang, Hyeon Jun Choi, Su Ji Bae, Dae Youn Hwang   +5 more
doaj   +1 more source

Quantitative trait loci for tibial bone strength in C57BL/6J and C3H/HeJ inbred strains of mice [PDF]

Journal of Genetics, 2010
Three-point bending technology has been widely used in the measurement of bone strength. Quantitative trait loci (QTLs) for bone strength have been identified using mouse femurs. In this study, we investigate the use of mouse tibiae in identification of QTLs that regulate bone strength. Mouse tibiae were from a F(2) population derived from C57BL/6J (B6)
Jiao, F, Chiu, H, Jiao, Y, de, Rijk W, Li, X, Eckstein, E C, Beamer, W G, Gu, W   +7 more
openaire   +2 more sources

Fecal IgA, Antigen Absorption, and Gut Microbiome Composition Are Associated With Food Antigen Sensitization in Genetically Susceptible Mice

Frontiers in Immunology, 2021
Food allergy is a potentially fatal disease affecting 8% of children and has become increasingly common in the past two decades. Despite the prevalence and severe nature of the disease, the mechanisms underlying sensitization remain to be further ...
Johanna M. Smeekens, Johanna M. Smeekens, Brandi T. Johnson-Weaver, Andrew L. Hinton, Andrew L. Hinton, M. Andrea Azcarate-Peril, M. Andrea Azcarate-Peril, Timothy P. Moran, Robert M. Immormino, Janelle R. Kesselring, Janelle R. Kesselring, Erin C. Steinbach, Kelly A. Orgel, Kelly A. Orgel, Herman F. Staats, Herman F. Staats, Herman F. Staats, A. Wesley Burks, A. Wesley Burks, Peter J. Mucha, Peter J. Mucha, Martin T. Ferris, Michael D. Kulis, Michael D. Kulis   +23 more
doaj   +1 more source

Immunological and nonimmunological control of severity of Trypanosoma musculi infections in C3H and C57BL/6 inbred mice [PDF]

Infection and Immunity, 1989
Studies concerned with the mechanisms responsible for relative resistance or susceptibility of strains of inbred mice to Trypanosoma musculi infections are presented. Treatment with 400 rads of ionizing radiation, silica dust, or trypan blue (reticuloendothelial blocking agents) rendered C3H mice unable to control the initial maximum level of parasite ...
J W, Albright, J F, Albright
openaire   +2 more sources

Lack of Association between the Tlr4 (Lps^d/Lps^d) Genotype and Increased Susceptibility to Escherichia coli Bladder Infections in Female C3H/HeJ Mice

mBio, 2011
Toll-like receptor 4 is thought to have a primary role in host defense against Escherichia coli bladder colonization, based on mouse models of urinary tract infection using C3H/HeJ female mice. This strain carries a point mutation in the Tlr4 gene, which
Kaleigh A. Suhs, Brodie R. Marthaler, Rodney A. Welch, Walter J. Hopkins   +3 more
doaj   +1 more source