Association of pulmonary lymphocytes with radiation-induced lung disease in a mouse model [PDF]
Radiation OncologyBackground Specific congenic mice derived from inbred C3H/HeJ mice, which present early onset pneumonitis, and C57BL/6J mice manifesting later onset pneumonitis with pulmonary fibrosis, vary in time to respiratory distress from these responses following ...
Laetitia Sabatier +3 more
doaj +2 more sources
Inbred Strain-Specific Response to Biglycan Deficiency in the Cortical Bone of C57BL6/129 and C3H/He Mice [PDF]
Journal of Bone and Mineral Research, 2009 Abstract Inbred strain-specific differences in mice exist in bone cross-sectional geometry, mechanical properties, and indices of bone formation. Inbred strain-specific responses to external stimuli also exist, but the role of background strain in response to genetic deletion is not fully understood.
Joseph M Wallace, David Köhn
exaly +3 more sources
Bone Loss and TLR4 Signals Contribute Independently to B Lineage Aging. [PDF]
Aging CellThe prevailing view is that the age‐related decline of B lymphopoiesis is due to increased inhibitory signals in the marrow environment. Our data show that the loss of salutary ones, such as those from bone, primarily drives the loss of B cell progenitors with age.
Baker E +6 more
europepmc +2 more sources
A lung cancer mouse model system based on an inbred C3H strain: Ultrasound imaging, pathological analysis, and proteomic biomarker identification [PDF]
Veterinary WorldBackground and Aim: Lung cancer remains a leading cause of global mortality, necessitating robust animal models for research into its mechanisms and therapeutic options.
Ulayatul Kustiati +6 more
doaj +2 more sources
Quantitative Trait Loci for Femoral and Lumbar Vertebral Bone Mineral Density in C57BL/6J and C3H/HeJ Inbred Strains of Mice [PDF]
Journal of Bone and Mineral Research, 2001 Abstract Significant differences in vertebral (9%) and femoral (50%) adult bone mineral density (BMD) between the C57BL/6J (B6) and C3H/HeJ (C3H) inbred strains of mice have been subjected to genetic analyses for quantitative trait loci (QTL).
Gary Churchill +2 more
exaly +4 more sources
Differential Effects of Bone Structural and Material Properties on Bone Competence in C57BL/6 and C3H/He Inbred Strains of Mice [PDF]
Calcified Tissue International, 2008 Calcified Tissue International, 83 (1)
Ralph Müller +2 more
exaly +6 more sources
Insights Into Complex Murine Models of Allergy and Anaphylaxis: The Central Role of IgE and Mast Cells in Advancing Human Therapies. [PDF]
Eur J ImmunolMurine allergy model outcomes differ by sensitization route, allergen type, and mouse strain, influencing mechanisms such as IgE and mast cell involvement and the therapeutic relevance of each model. Understanding how experimental parameters shape outcomes is essential for selecting appropriate models and effectively translating findings to clinical ...
Nagata Y, Suzuki R.
europepmc +2 more sources
Lymphatic topology reveals a novel intranodal lympho-venous shunt. [PDF]
J PatholAbstract Understanding the lymphatic network is crucial for immunological research. Currently, a complete map of lymphatic drainage in mice is lacking. We present a detailed lymphatic system flow dynamic of two mouse strains with swollen lymph nodes (LNs), using region‐specific tracer injection and high‐resolution micro‐CT imaging to characterize LN ...
Sukhbaatar A +5 more
europepmc +2 more sources
THE ESTABLISHMENT OF THE C3H INBRED STRAIN OF MICE FOR THE STUDY OF SPONTANEOUS CARCINOMA OF THE MAMMARY GLAND [PDF]
Genetics, 1935 L C Strong, Strong Leonell C
exaly +4 more sources
A DIFFERENCE IN SKELETAL TYPE BETWEEN RECIPROCAL HYBRIDS OF TWO INBRED STRAINS OF MICE (C57 BLK AND C3H) [PDF]
Genetics, 1951 E L Green
exaly +3 more sources