Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology. [PDF]
PLoS ONE, 2014 The female lower genital tract is constantly exposed to microbial infection, some of which can ascend to and cause pathology such as hydrosalpinx in the upper genital tract, which can affect fertility.
Jianlin Chen +9 more
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Inbred Strain-Specific Effects of Exercise in Wild Type and Biglycan Deficient Mice [PDF]
, 2010 Biglycan (bgn)-deficient mice (KO) have defective osteoblasts which lead to changes in the amount and quality of bone. Altered tissue strength in C57BL6/129 (B6;129) KO mice, a property which is independent of tissue quantity, suggests that deficiencies ...
Darling, Eric M. +4 more
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Occurrence of Urinary Calculi in Inbred Strain (C3H) of Mice Treated with Estrogen
Experimental Biology and Medicine, 1939 SummaryUrinary calculi occurred in 33.1% of the 151 strain C3H male mice treated with estogren, and in 4.1% of 96 controls. The highest incidence was noted in mice 5 months of age or older, which had received from 9 to 20 weekly injections of 100 rat units. The calculi appeared at an earlier age in the treated animals.
E. L. Burns, J. R. Schenken
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Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse. [PDF]
, 2017 Current antipsychotic medications used to treat schizophrenia all target the dopamine D2 receptor. Although these drugs have serious side effects and limited efficacy, no novel molecular targets for schizophrenia treatment have been successfully ...
Boutros, PC +5 more
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Site and strain-specific variation in gut microbiota profiles and metabolism in experimental mice. [PDF]
PLoS ONE, 2010 The gastrointestinal tract microbiota (GTM) of mammals is a complex microbial consortium, the composition and activities of which influences mucosal development, immunity, nutrition and drug metabolism.
Melissa K Friswell +6 more
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Cocaine-Induced Locomotor Activation Differs Across Inbred Mouse Substrains
Frontiers in Psychiatry, 2022 Cocaine use disorders (CUD) are devastating for affected individuals and impose a significant societal burden, but there are currently no FDA-approved therapies.
Christiann H. Gaines +16 more
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Immunochemical analysis of antigenic properties of MH134 ascitic hepatoma [PDF]
, 1965 According to the data obtained in this experiment by means of the geldiffusion technique, the specific antigen was not detected in MH134 ascitic tumor, comparing the anti-C3H liver sera with anti-MH 134 tumor sera, though a loss of organ specific antigen
Tai, Chiaki
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PLoS ONE, 2013 Transcription Activator-Like Effector Nucleases (TALENs) consist of a nuclease domain fused to a DNA binding domain which is engineered to bind to any genomic sequence.
Benjamin Davies +5 more
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Marked mitigation of transplant vascular sclerosis in FasL(gld) (CD95L) mutant recipients. I. The role of alloantibodies in the development of chronic rejection [PDF]
, 1999 Background. In the acute rejection of allografts, the interaction between Fas (CD95) and its ligand (FasL; CD95L) has been shown to be involved in mediating apoptotic cell death.
Aitouche, A +7 more
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Memorias do Instituto Oswaldo Cruz, 1998 Worm burdens recovered from inbred mice strains, namely C57Bl/6, C57Bl/10, CBA, BALB/c, DBA/2 and C3H/He, conventionally maintained in two institutional animal houses in the State of Rio de Janeiro, RJ, Brazil, were analyzed and compared, regarding their
Lucineide Gonçalves +4 more
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