Immobilization induced osteopenia is strain specific in mice
Bone Reports, 2015 Immobilization causes rapid and massive bone loss. By comparing Botulinum Toxin A (BTX)-induced bone loss in mouse strains with different genetic backgrounds we investigated whether the genetic background had an influence on the severity of the ...
Andreas Lodberg +5 more
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Occurrence of Urinary Calculi in Inbred Strain (C3H) of Mice Treated with Estrogen
Experimental Biology and Medicine, 1939 SummaryUrinary calculi occurred in 33.1% of the 151 strain C3H male mice treated with estogren, and in 4.1% of 96 controls. The highest incidence was noted in mice 5 months of age or older, which had received from 9 to 20 weekly injections of 100 rat units. The calculi appeared at an earlier age in the treated animals.
E. L. Burns, J. R. Schenken
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Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping
Frontiers in Genetics, 2019 The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF bone development
Heather Zimmerman +4 more
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Host genetic background influences the response to the opportunistic Pseudomonas aeruginosa infection altering cell-mediated immunity and bacterial replication. [PDF]
PLoS ONE, 2014 Pseudomonas aeruginosa is a common cause of healthcare-associated infections including pneumonia, bloodstream, urinary tract, and surgical site infections. The clinical outcome of P.
Maura De Simone +7 more
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Lysed Enterococcus faecalis FK-23 (LFK) Suppressing Allergic Responses in Mouse Models
Allergology International, 2005 Recently, several clinical trials have been published to discuss the possibility of probiotic supplementation, especially some products of lactic acid bacteria such as Lactobacillus and Bifidobacterium strains, in prevention and treatment of allergic ...
Takashi Shimada +6 more
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Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology. [PDF]
PLoS ONE, 2014 The female lower genital tract is constantly exposed to microbial infection, some of which can ascend to and cause pathology such as hydrosalpinx in the upper genital tract, which can affect fertility.
Jianlin Chen +9 more
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Site and strain-specific variation in gut microbiota profiles and metabolism in experimental mice. [PDF]
PLoS ONE, 2010 The gastrointestinal tract microbiota (GTM) of mammals is a complex microbial consortium, the composition and activities of which influences mucosal development, immunity, nutrition and drug metabolism.
Melissa K Friswell +6 more
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Cocaine-Induced Locomotor Activation Differs Across Inbred Mouse Substrains
Frontiers in Psychiatry, 2022 Cocaine use disorders (CUD) are devastating for affected individuals and impose a significant societal burden, but there are currently no FDA-approved therapies.
Christiann H. Gaines +16 more
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PLoS ONE, 2013 Transcription Activator-Like Effector Nucleases (TALENs) consist of a nuclease domain fused to a DNA binding domain which is engineered to bind to any genomic sequence.
Benjamin Davies +5 more
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Memorias do Instituto Oswaldo Cruz, 1998 Worm burdens recovered from inbred mice strains, namely C57Bl/6, C57Bl/10, CBA, BALB/c, DBA/2 and C3H/He, conventionally maintained in two institutional animal houses in the State of Rio de Janeiro, RJ, Brazil, were analyzed and compared, regarding their
Lucineide Gonçalves +4 more
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