Results 31 to 40 of about 15,270 (172)

Host genetic background influences the response to the opportunistic Pseudomonas aeruginosa infection altering cell-mediated immunity and bacterial replication. [PDF]

PLoS ONE, 2014
Pseudomonas aeruginosa is a common cause of healthcare-associated infections including pneumonia, bloodstream, urinary tract, and surgical site infections. The clinical outcome of P.
Maura De Simone, Lorenza Spagnuolo, Nicola Ivan Lorè, Giacomo Rossi, Cristina Cigana, Ida De Fino, Fuad A Iraqi, Alessandra Bragonzi   +7 more
doaj   +1 more source

Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology. [PDF]

PLoS ONE, 2014
The female lower genital tract is constantly exposed to microbial infection, some of which can ascend to and cause pathology such as hydrosalpinx in the upper genital tract, which can affect fertility.
Jianlin Chen, Hongbo Zhang, Zhou Zhou, Zhangsheng Yang, Yiling Ding, Zhiguang Zhou, Edward Zhong, Bernard Arulanandam, Joel Baseman, Guangming Zhong   +9 more
doaj   +1 more source

Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes.

PLoS ONE, 2013
Transcription Activator-Like Effector Nucleases (TALENs) consist of a nuclease domain fused to a DNA binding domain which is engineered to bind to any genomic sequence.
Benjamin Davies, Graham Davies, Christopher Preece, Rathi Puliyadi, Dorota Szumska, Shoumo Bhattacharya   +5 more
doaj   +1 more source

Site and strain-specific variation in gut microbiota profiles and metabolism in experimental mice. [PDF]

PLoS ONE, 2010
The gastrointestinal tract microbiota (GTM) of mammals is a complex microbial consortium, the composition and activities of which influences mucosal development, immunity, nutrition and drug metabolism.
Melissa K Friswell, Helen Gika, Ian J Stratford, Georgios Theodoridis, Brian Telfer, Ian D Wilson, Andrew J McBain   +6 more
doaj   +1 more source

Cocaine-Induced Locomotor Activation Differs Across Inbred Mouse Substrains

Frontiers in Psychiatry, 2022
Cocaine use disorders (CUD) are devastating for affected individuals and impose a significant societal burden, but there are currently no FDA-approved therapies.
Christiann H. Gaines, Christiann H. Gaines, Sarah A. Schoenrock, Joseph Farrington, David F. Lee, David F. Lee, Lucas J. Aponte-Collazo, Lucas J. Aponte-Collazo, Ginger D. Shaw, Ginger D. Shaw, Darla R. Miller, Darla R. Miller, Martin T. Ferris, Fernando Pardo-Manuel de Villena, Fernando Pardo-Manuel de Villena, Lisa M. Tarantino, Lisa M. Tarantino   +16 more
doaj   +1 more source

Helminth Parasites of Conventionally Maintained Laboratory Mice: II- Inbred Strains with an Adaptation of the Anal Swab Technique

Memorias do Instituto Oswaldo Cruz, 1998
Worm burdens recovered from inbred mice strains, namely C57Bl/6, C57Bl/10, CBA, BALB/c, DBA/2 and C3H/He, conventionally maintained in two institutional animal houses in the State of Rio de Janeiro, RJ, Brazil, were analyzed and compared, regarding their
Lucineide Gonçalves, Roberto Magalhães Pinto, J Júlio Vicente, Dely Noronha, Delir Corrêa Gomes   +4 more
doaj   +1 more source

Genetic analysis of intestinal cholesterol absorption in inbred mice

Journal of Lipid Research, 2001
A genetic mapping strategy was employed to identify chromosomal regions harboring genes that influence the absorption of intestinal cholesterol in the mouse.
Margrit Schwarz, Daphne L. Davis, Bertrand R. Vick, David W. Russell   +3 more
doaj   +1 more source

In vivo microscopic voxel-based morphometry with a brain template to characterize strain-specific structures in the mouse brain

Scientific Reports, 2017
Hundreds of inbred mouse strains are established for use in a broad spectrum of basic research fields, including genetics, neuroscience, immunology, and cancer.
Keigo Hikishima, Yuji Komaki, Fumiko Seki, Yasuyuki Ohnishi, Hirotaka J. Okano, Hideyuki Okano   +5 more
doaj   +1 more source

A dominant X-linked QTL regulating pubertal timing in mice found by whole genome scanning and modified interval-specific congenic strain analysis. [PDF]

PLoS ONE, 2008
BackgroundPubertal timing in mammals is triggered by reactivation of the hypothalamic-pituitary-gonadal (HPG) axis and modulated by both genetic and environmental factors. Strain-dependent differences in vaginal opening among inbred mouse strains suggest
Wangsheng Zhu, Zhongpeng Fan, Chao Zhang, Zhengxia Guo, Ying Zhao, Yuxun Zhou, Kai Li, Zhenghong Xing, Guoqiang Chen, Yinming Liang, Li Jin, Junhua Xiao   +11 more
doaj   +1 more source

Increased Variation in Body Weight and Food Intake Is Related to Increased Dietary Fat but Not Increased Carbohydrate or Protein in Mice

Frontiers in Nutrition, 2022
A variety of inbred mouse strains have been used for research in metabolic disorders. Despite being inbred, they display large inter-individual variability for many traits like food intake and body weight.
Yingga Wu, Yingga Wu, Yingga Wu, Sumei Hu, Sumei Hu, Dengbao Yang, Li Li, Li Li, Baoguo Li, Baoguo Li, Lu Wang, Lu Wang, Lu Wang, Min Li, Min Li, Min Li, Min Li, Guanlin Wang, Guanlin Wang, Guanlin Wang, Jianbo Li, Yanchao Xu, Xueying Zhang, Xueying Zhang, Xueying Zhang, Xueying Zhang, Chaoqun Niu, Chaoqun Niu, John R. Speakman, John R. Speakman, John R. Speakman, John R. Speakman   +31 more
doaj   +1 more source