Results 21 to 30 of about 15,253 (172)
PLoS ONE, 2016 Genetic make-up strongly influences the skeleton's susceptibility to the loss of weight bearing with some inbred mouse strains experiencing great amounts of bone loss while others lose bone at much smaller rates. At young adulthood, female inbred C3H/HeJ
Bing Li +2 more
doaj +1 more source
Polyoma virus-induced osteosarcomas in inbred strains of mice: host determinants of metastasis. [PDF]
PLoS Pathogens, 2010 The mouse polyoma virus induces a broad array of solid tumors in mice of many inbred strains. In most strains tumors grow rapidly but fail to metastasize.
Palanivel Velupillai +6 more
doaj +1 more source
Frontiers in Neuroscience, 2021 Although studies with inbred strains of mice have shown that infarct size is largely determined by the extent of collateral vessel connections between arteries in the brain that enable reperfusion of the ischemic territory, we have identified strain ...
Han Kyu Lee +3 more
doaj +1 more source
Frequent DNA Polymorphisms Exist in Inbred CBA/J and C3H/HeN Mice
Genomics, 1996 Although occasional DNA polymorphisms have been observed in inbred mice, CBA/J and C3H/HeN mice have two microsatellite alleles at over 1/3 of microsatellite loci tested. Since DNA polymorphisms were not detected in DBA/2J, C57BL/6J, and BALB/cJ, the frequency of microsatellite polymorphisms appears to be strain specific.
B, Yuan +4 more
openaire +2 more sources
Quantitative trait loci for tibial bone strength in C57BL/6J and C3H/HeJ inbred strains of mice [PDF]
Journal of Genetics, 2010 Three-point bending technology has been widely used in the measurement of bone strength. Quantitative trait loci (QTLs) for bone strength have been identified using mouse femurs. In this study, we investigate the use of mouse tibiae in identification of QTLs that regulate bone strength. Mouse tibiae were from a F(2) population derived from C57BL/6J (B6)
Jiao, F +7 more
openaire +2 more sources
Effects of atherogenic diet consumption on lipoproteins in mouse strains C57BL/6 and C3H
Journal of Lipid Research, 1991 Inbred mouse strains C57BL/6J (B6) (susceptible) and C3H/HeJ (C3H) (resistant) differ in atherosclerosis susceptibility due to a single gene, Ath-1. Plasma lipoproteins from female mice fed chow or an atherogenic diet displayed strain differences in ...
BY Ishida +4 more
doaj +1 more source
Unraveling genetic modifiers in the gria4 mouse model of absence epilepsy. [PDF]
PLoS Genetics, 2014 Absence epilepsy (AE) is a common type of genetic generalized epilepsy (GGE), particularly in children. AE and GGE are complex genetic diseases with few causal variants identified to date.
Wayne N Frankel +4 more
doaj +1 more source
Cocaine locomotor activation, sensitization and place preference in six inbred strains of mice
Behavioral and Brain Functions, 2011 Background The expanding set of genomics tools available for inbred mouse strains has renewed interest in phenotyping larger sets of strains. The present study aims to explore phenotypic variability among six commonly-used inbred mouse strains to both ...
Grabowski-Boase Laura +2 more
doaj +1 more source
Bone Reports, 2018 The long term skeletal effects of antenatal exposure to teratogen 5-deoxy-2′-cytidine (5-AZA) were studied using two inbred strains, C3H/HeJ (C3H, with inherently stronger bones) and C57Bl/6J (C57, with weaker bones). We previously reported that in-utero
Deepak Kumar Khajuria +7 more
doaj +1 more source
Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains [PDF]
Drug and Alcohol Dependence, 2008 Drug abuse is common among adolescents and young adults. Although the consequences of intoxication are known, sequelae of drugs emerging on campuses and in clubs nationwide are not. We previously demonstrated that ketamine exposure results in lasting physiological abnormalities in mice.
Chalon R, Majewski-Tiedeken +2 more
openaire +2 more sources