Results 21 to 30 of about 15,270 (172)

Quantitative trait loci for tibial bone strength in C57BL/6J and C3H/HeJ inbred strains of mice [PDF]

Journal of Genetics, 2010
Three-point bending technology has been widely used in the measurement of bone strength. Quantitative trait loci (QTLs) for bone strength have been identified using mouse femurs. In this study, we investigate the use of mouse tibiae in identification of QTLs that regulate bone strength. Mouse tibiae were from a F(2) population derived from C57BL/6J (B6)
Jiao, F, Chiu, H, Jiao, Y, de, Rijk W, Li, X, Eckstein, E C, Beamer, W G, Gu, W   +7 more
openaire   +2 more sources

Effects of atherogenic diet consumption on lipoproteins in mouse strains C57BL/6 and C3H

Journal of Lipid Research, 1991
Inbred mouse strains C57BL/6J (B6) (susceptible) and C3H/HeJ (C3H) (resistant) differ in atherosclerosis susceptibility due to a single gene, Ath-1. Plasma lipoproteins from female mice fed chow or an atherogenic diet displayed strain differences in ...
BY Ishida, PJ Blanche, AV Nichols, M Yashar, B Paigen   +4 more
doaj   +1 more source

Unraveling genetic modifiers in the gria4 mouse model of absence epilepsy. [PDF]

PLoS Genetics, 2014
Absence epilepsy (AE) is a common type of genetic generalized epilepsy (GGE), particularly in children. AE and GGE are complex genetic diseases with few causal variants identified to date.
Wayne N Frankel, Connie L Mahaffey, Tracy C McGarr, Barbara J Beyer, Verity A Letts   +4 more
doaj   +1 more source

Cocaine locomotor activation, sensitization and place preference in six inbred strains of mice

Behavioral and Brain Functions, 2011
Background The expanding set of genomics tools available for inbred mouse strains has renewed interest in phenotyping larger sets of strains. The present study aims to explore phenotypic variability among six commonly-used inbred mouse strains to both ...
Grabowski-Boase Laura, Eisener-Dorman Amy F, Tarantino Lisa M   +2 more
doaj   +1 more source

Evaluation of the long-term skeletal effect induced by teratogen 5-aza-2′deoxycytidine on offspring of high (C3H/HeJ) and low (C57BL/6J) bone mass phenotype mice

Bone Reports, 2018
The long term skeletal effects of antenatal exposure to teratogen 5-deoxy-2′-cytidine (5-AZA) were studied using two inbred strains, C3H/HeJ (C3H, with inherently stronger bones) and C57Bl/6J (C57, with weaker bones). We previously reported that in-utero
Deepak Kumar Khajuria, Maria Raygorodskaya, Eugene Kobyliansky, Yankel Gabet, Sahar Hiram Bab, Chen Shochat, Arkady Torchinsky, David Karasik   +7 more
doaj   +1 more source

Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping

Frontiers in Genetics, 2019
The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF bone development
Heather Zimmerman, Zhaoyu Yin, Fei Zou, Eric T. Everett, Eric T. Everett   +4 more
doaj   +1 more source

Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains [PDF]

Drug and Alcohol Dependence, 2008
Drug abuse is common among adolescents and young adults. Although the consequences of intoxication are known, sequelae of drugs emerging on campuses and in clubs nationwide are not. We previously demonstrated that ketamine exposure results in lasting physiological abnormalities in mice.
Chalon R, Majewski-Tiedeken, Cara R, Rabin, Steven J, Siegel   +2 more
openaire   +2 more sources

Immobilization induced osteopenia is strain specific in mice

Bone Reports, 2015
Immobilization causes rapid and massive bone loss. By comparing Botulinum Toxin A (BTX)-induced bone loss in mouse strains with different genetic backgrounds we investigated whether the genetic background had an influence on the severity of the ...
Andreas Lodberg, Jens Bay Vegger, Michael Vinkel Jensen, Christian Mirian Larsen, Jesper Skovhus Thomsen, Annemarie Brüel   +5 more
doaj   +1 more source

Occurrence of Urinary Calculi in Inbred Strain (C3H) of Mice Treated with Estrogen

Experimental Biology and Medicine, 1939
SummaryUrinary calculi occurred in 33.1% of the 151 strain C3H male mice treated with estogren, and in 4.1% of 96 controls. The highest incidence was noted in mice 5 months of age or older, which had received from 9 to 20 weekly injections of 100 rat units. The calculi appeared at an earlier age in the treated animals.
E. L. Burns, J. R. Schenken
openaire   +1 more source

Lysed Enterococcus faecalis FK-23 (LFK) Suppressing Allergic Responses in Mouse Models

Allergology International, 2005
Recently, several clinical trials have been published to discuss the possibility of probiotic supplementation, especially some products of lactic acid bacteria such as Lactobacillus and Bifidobacterium strains, in prevention and treatment of allergic ...
Takashi Shimada, Lei Cheng, Chie Motonaga, Hai-Bo Shi, Akiko Yamasaki, Tadao Enomoto, Taro Shirakawa   +6 more
doaj   +1 more source