Results 161 to 170 of about 195,634 (228)

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, Volume 78, Issue 6, Page 1196-1205, June 2026.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Spermine Oxidase Serves as a Key Functional Node in Microbial Dysbiosis-Induced Breast Carcinogenesis. [PDF]

Cancer Res
Nandi D, Parida S, Verma D, Foley JR, Stewart TM, Korangath P, Thatikonda S, Siddharth S, Wu Q, Yi M, Bishai W, Ivkov R, Sears CL, Casero RA, Sharma D.   +14 more
europepmc   +1 more source

A working model for CCN3 C‐terminal domain‐mediated transcriptional modulation of the plasminogen activation system

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Plasminogen is a circulating zymogen that is converted into active plasmin by plasminogen activators such as tissue plasminogen activator (tPA) and urokinase‐type PA (uPA). This conversion is regulated by plasminogen activator inhibitors (PAI‐1, PAI‐2) and by inhibitors of plasmin itself, maintaining a fine balance between activation and inhibition of ...
Bernard Perbal
wiley   +1 more source

Exploring the Molecular and Genomic Landscape of the Dark Agouti Rat Mammary Adenocarcinoma: Preliminary Insights for Triple-Negative Breast Cancer Modeling. [PDF]

J Mammary Gland Biol Neoplasia
Dikeocha IJ, Oliva A, Bateman E, Wardill HR, Bowen JM.   +4 more
europepmc   +1 more source

Clinical and Pathological Characteristics and Prognosis of Breast Cancer During Pregnancy and Postpartum: A Multicenter Retrospective Study

Cancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Purpose The prognostic impact of the interval between the most recent childbirth and breast cancer diagnosis remains insufficiently defined, particularly when breast cancer diagnosed during pregnancy (PrBC) is distinguished from postpartum breast cancer (PPBC).
Liying Wang, Heran Deng, Xiaoyu Fang, TaoLang Li, Qianjun Chen, Jieqiong Liu   +5 more
wiley   +1 more source

Genistein Supplementation Affects Mineral Homeostasis in Rats with Mammary Cancer. [PDF]

Foods
Skrajnowska D, Szterk A, Ofiara K, Kowalczyk P, Strus B, Bobrowska-Korczak B.   +5 more
europepmc   +1 more source

Assessment of Doxorubicin Internalization and Cytotoxicity in Primary Tumor Spheroids After Collagen Digestion

Current Protocols, Volume 6, Issue 6, June 2026.
Abstract The limited penetration of chemotherapeutic agents into solid tumors remains a major obstacle to effective cancer treatment and is strongly influenced by the extracellular matrix (ECM). Three‐dimensional (3D) tumor spheroids derived from primary tumor cells (PTCs) represent a valuable in vitro model to study how ECM composition and ...
Alessandra Lo Cicero, Gabriele Lo Buglio, Simona Campora, Giulio Ghersi   +3 more
wiley   +1 more source

Pleiotrophin in Mammary Gland Development and Breast Cancer: A Comprehensive Review of the Evidence. [PDF]

Cells
Gholami AS, Walsh CN, McBryan J.
europepmc   +1 more source

Single‐cell profiling reveals peripheral blood immune landscape remodelling in breast cancer lymph node metastasis

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
scRNA‐seq reveals pro‐metastatic neutrophil and exhausted T/NK subsets in BC patients with LN metastasis. Interferon‐stimulated neutrophils secrete LGALS9, drives T/NK cell exhaustion via HAVCR2. Neutralising LGALS9 restores T‐cell anti‐tumour activity, suggesting a novel therapeutic target.
Bo Chen, Kang Ma, Yunjie Wang, Liulu Zhang, Xinyue Feng, Cheng Long, Xuejing Tan, Kun Wang   +7 more
wiley   +1 more source

Distribution of neoplasia in Danish cats: data from the Danish Veterinary Cancer Registry. [PDF]

J Feline Med Surg
Børresen B, Anker Heden M, Thuri Kristensen A.   +2 more
europepmc   +1 more source