Distinct expression patterns of ER alpha and ER beta in normal human mammary gland [PDF]
AIM: Two oestrogen receptors (ERs) have been identified to date—the “classic” ERa and the more recently described ERb. Although much is known about ERa at the mRNA and protein levels, our knowledge of the expression and distribution of ERb protein is ...
Burdall, S.E. +3 more
core
Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis. [PDF]
Most BRCA1-associated breast tumours are basal-like yet originate from luminal progenitors. BRCA1 is best known for its functions in double-strand break repair and resolution of DNA replication stress.
Angel Pujana, Miguel +29 more
core +2 more sources
Incidence of P200 pemphigoid: A nationwide study
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen +7 more
wiley +1 more source
Background: Obese subjects with breast hypertrophy are suffering not only from cosmetic aspects but also negatively affecting the quality of their life so, the aim of this study was to evaluate the effect of weight reduction versus reduction-mammoplasty ...
Ramadan Nafae +6 more
doaj +1 more source
Risk and protective factors affecting sensory recovery after breast reconstruction
Background Although loss of sensation in patients with breast cancer after mastectomy followed by breast reconstruction is an important factor affecting patients’ quality of life, the mechanism of sensory recovery is still unclear.
Jae Young Bae +3 more
doaj +1 more source
Changes in epithelial proportions and transcriptional state underlie major premenopausal breast cancer risks [PDF]
The human breast undergoes lifelong remodeling in response to estrogen and progesterone, but hormone exposure also increases breast cancer risk. Here, we use single-cell analysis to identify distinct mechanisms through which breast composition and cell ...
Borowsky, Alexander D. +10 more
core +1 more source
Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. [PDF]
The mammary epithelium depends on specific lineages and their stem and progenitor function to accommodate hormone-triggered physiological demands in the adult female.
Abe +111 more
core +2 more sources
Impact of aesthetic mammoplasty on the self-esteem of women from a northeastern capital [PDF]
Introduction: The main reason that leads someone to undergo aesthetic surgery is the need to obtain approval and affection from other people, which, consequently, enhances self-esteem.
Gabriela Rezende Santos +7 more
doaj +1 more source
Parity-related molecular signatures and breast cancer subtypes by estrogen receptor status [PDF]
INTRODUCTION: Relationships of parity with breast cancer risk are complex. Parity is associated with decreased risk of postmenopausal hormone receptor–positive breast tumors, but may increase risk for basal-like breast cancers and early-onset tumors ...
A Subramanian +61 more
core +3 more sources

