Results 131 to 140 of about 45,459 (191)

Explore the Mechanism of Xiaoyaosan for Treatment of Bipolar Disorder Based on Network Pharmacology, Experimental Validation and Molecular Docking

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This study evaluates Xiaoyaosan (XYS) for bipolar disorder (BD) using network pharmacology and experimental validation. Molecular docking reveals interactions between active XYS compounds and potential core targets. Animal experiments confirm XYS alleviates BD‐like behaviors in mice by suppressing core targets, elucidating its multi‐target mechanism ...
Man Chen, Nana Ding, Xingmin Qiu, Lan Li, Yali Guo, Rongyanqi Wang, Xiaowei Mo, Tan Zou, Shangzhen Yu, Xiaojuan Li, Jiaxu Chen   +10 more
wiley   +1 more source

Feeling Better Before, Not After: An Ecological Momentary Assessment of Affect Around Exercise in Women With Eating Disorders

International Journal of Eating Disorders, Volume 59, Issue 10, Page 2247-2258, October 2026.
ABSTRACT Objective Maladaptive exercise includes excessive, compulsive, or compensatory exercise and is a common eating‐disorder (ED) symptom associated with increased severity, slower rates‐of‐recovery, and faster rates‐of‐relapse. Affect‐regulation theories posit that maladaptive exercise functions to reduce high negative affect (NA), although ...
Danielle A. N. Chapa, Kelsie T. Forbush, Yiyang Chen, Courtney E. Costain, Samiya I. Rasheed   +4 more
wiley   +1 more source

Neural Markers of Reward Valuation and Impulsive Decision-Making in Mania Risk.

JAMA Psychiatry
Raeder R, Arora M, Jones N, Chase HW, Bertocci M, Roberts LT, Bebko G, Aslam HA, Graur S, Taylor M, Atkinson M, Benjamin O, Wang Y, Stiffler R, Phillips ML.   +14 more
europepmc   +1 more source

Virtual Horizons in Medicine: The Role of the Metaverse in Transforming Medical Education—A Qualitative Scoping Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background The metaverse is defined as a three‐dimensional, interactive and persistent virtual space in which users interact with one another and with simulated environments through digital avatars. This technology, as an innovative approach to education and learning, holds transformative potential for medical education.
Fariba Khanipoor, Zahra Karimian
wiley   +1 more source

Neuroendocrine and psychosocial triggers of severe psychiatric onset in women: a systematic review with domain-specific quantitative and narrative synthesis. [PDF]

Front Psychiatry
Kilincel S, Bulut F, Akpinar Aslan E, Kilincel O.   +3 more
europepmc   +1 more source

Profiles of Early Life Stress and Their Interaction With Proximal Stress in Early Adulthood: A Person‐Centered Approach

Journal of Clinical Psychology, Volume 82, Issue 10, Page 1498-1508, October 2026.
ABSTRACT Objective Adverse effects of early life stress (ELS) exposure are well‐documented, but the joint effects of multiple exposures to different types of ELS (e.g., abuse, neglect, family dysfunction, maladaptive parenting) and their interaction with more proximal stress in adulthood remains less understood.
Juhyun Park, Clara Freeman, Seonwoo Hong, Anna Weinberg   +3 more
wiley   +1 more source

Chronic Liver Disease Self‐Management for Veterans: A Feasibility Trial

Lifestyle Medicine, Volume 7, Issue 4, October 2026.
ABSTRACT Background Rates of chronic liver disease (CLD) related to obesity and other cardiometabolic risk factors have increased dramatically and contribute to significant health burden and mortality. Lifestyle modification is commonly recommended, with a focus on nutrition, exercise, medication adherence, screening for CLD complications, and active ...
Carol Gonzalez, Ann Deioma, Heather M. Patton, Erik J. Groessl   +3 more
wiley   +1 more source

Risk‐Stratified Bilateral Tonsillectomy for Unilateral HPV‐Associated Tonsillar SCC: Oncologic and Functional Outcomes From a Single Institution

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 5, October 2026.
The role of contralateral tonsillectomy in unilateral HPV+ tonsillar squamous cell carcinoma (TSCC) is debated. Among 163 patients with p16‐positive TSCC, occult synchronous contralateral second primary malignancies clustered among patients with high‐risk preoperative features (20.0%) compared with low‐risk patients (6.7%, number needed to treat 14 ...
Tereza Vitkovska, Crystal Z. Zhou, Ishna Pandey, Maxwell L. Weng, Lauran K. Evans, Song Hon Hwang, Christian Wooten, Dipti Sajed, Maie A. St. John   +8 more
wiley   +1 more source

High Risk of Metabolic Side Effects Among New Paediatric Antipsychotic Users in Sweden—A Register‐Based Study

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose This study aims to assess the risk of metabolic side effects among paediatric new users of antipsychotics in Sweden, focusing on differences between substances and sexes. Methods Children aged 5–17 years, who were new users of antipsychotics between 2014 and 2021, were identified using Swedish national health registers.
Elin Eyfells Kimland, Anders Sundström, Sverre Wikström, Håkan Jarbin, Elin Dahlén   +4 more
wiley   +1 more source