Results 61 to 70 of about 47,190 (223)

Fármacos que imitan o exacerban trastornos psiquiátricos Drugs that mimic or exacerbate psychiatric disorders

open access: yesIatreia, 1995
Muchas sustancias pueden producir efectos sobre el sistema nervioso central, incluso las que se usan primariamente por sus acciones periféricas; además, los agentes cuyo beneficio terapéutico se basa en una acción central, se prescriben comúnmente para ...
Luis Carlos Mejía Rivera   +1 more
doaj  

Behavioral manifestations and underlying mechanisms of amphetamine in constructing animal models of mania: a comprehensive review

open access: yesFrontiers in Neuroscience
Mania is a mind disorder with heightened emotions, etc. Amphetamine (AMPH), a drug with central nervous system excitatory effects, can disrupt neurotransmitter release and metabolism, causing mania. AMPH-induced animal models of mania show increased risk
Zi-Qi Deng   +10 more
doaj   +1 more source

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino   +3 more
wiley   +1 more source

Usos de la droga

open access: yesDesde el Jardín de Freud, 2007
Este texto está dedicado a hacer un examen de la relación del sujeto con la droga, tomada como objeto de goce y teniendo en cuenta las variaciones subjetivas que en dicha relación pueden ser localizadas.
Héctor Gallo
doaj  

Delirious mania: Clinical course and treatment

open access: yesPsychiatry and Behavioral Sciences, 2015
Delirious mania (DM) is a syndrome consists of both mania and delirium, generally with accompanying catatonic features. Symptoms occur in hours or days with or without autonomic symptoms and if it is not treated properly, the clinical course get worse ...
Aylin Can   +3 more
doaj   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

Brain-derived neurotrophic factor protein and mRNA levels in patients with bipolar mania – A preliminary study

open access: yesBiomedical Journal, 2016
Background: Brain-derived neurotrophic factor (BDNF) protein or mRNA levels may be involved in the pathophysiology of bipolar disorder. However, the results were inconsistent.
Chin-Chuen Lin   +3 more
doaj   +1 more source

From settler gardens to digital naturalists: human aesthetic preferences and land use changes facilitate the biogeographical expansion of a wild plant–virus interaction

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Anthropogenic facilitation of wild plants based on aesthetic preferences for particular traits can change the biogeography and ecology of natural communities. We use a mixed‐methods socioecological approach to characterize the ways in which humans interact with a common, widely distributed plant and a generalist viral symbiont that induces an ...
Elizabeth M. Lombardi   +3 more
wiley   +1 more source

Market Integration and Nonlinear Price Transmission in 19th‐Century British Wheat Markets

open access: yesJournal of Agricultural Economics, EarlyView.
ABSTRACT Important developments in infrastructure and institutions characterized 19th‐Century wheat markets in Great Britain. Among these developments was the construction of the national rail system which enabled cheaper and more efficient transport of grain and other bulky cargoes between inland towns and ports.
Barry K. Goodwin, A. Ford Ramsey
wiley   +1 more source

Developmental Trauma as a Prognostic Factor for Later Psychotic Disorder in an Adolescent Clinical Cohort: A 20‐Year Follow Up Study

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background and Hypothesis Recent studies demonstrate that individuals who attend psychiatric services in adolescence, especially inpatient care, have an increased risk of psychotic disorders in adulthood. Given the extensive literature demonstrating a relationship between developmental trauma and psychosis, we investigated whether trauma ...
Valentina Kieseppä   +5 more
wiley   +1 more source

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