Results 51 to 60 of about 943,855 (206)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Canadian Respiratory Journal, 2002 Carcinoid tumours of the thymus are rare. The case of a 57-year-old asymptomatic man with a carcinoid tumour of the thymus, who showed a widened mediastinum by chest x-ray, is presented. Fine needle aspiration suggested the diagnosis, which was confirmed
Isabel Parra +3 more
doaj +1 more source
Spartan Daily, May 11, 1959 [PDF]
, 1959 Volume 46, Issue 123https://scholarworks.sjsu.edu/spartandaily/3902/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
$\gamma$-ray spectra and enhancement factors for positron annihilation spectra with core-electrons [PDF]
, 2015 Many-body theory is developed to calculate the $\gamma$-spectra for positron annihilation with valence and core electrons in the noble gas atoms. A proper inclusion of correlation effects and core annihilation provides for an accurate description of the ...
Green, D. G., Gribakin, G. F.
core +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Spartan Daily, October 8, 1959 [PDF]
, 1957 Volume 47, Issue 12https://scholarworks.sjsu.edu/spartandaily/3928/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
, 2011 Most celebrated artists are as influential artistically as they are critically. Beuys’ reception to date, remains controversial and contradictory; his artistic influence is unquestioned but this is not matched by his critical acclaim.
Foster, Nicola
core +1 more source
His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]
, 1988 The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M. +3 more
core +1 more source