Results 51 to 60 of about 3,469,267 (257)

A new DCache prefetch algorithm based on branch prediction information for AI industrial engineering

open access: yesAcademia Engineering
Introduction: This work proposes a novel cache prefetching algorithm and corresponding microarchitecture for high-performance Central Processing Unit (CPU) designs. Existing stride-based and conventional DCache prefetching schemes have limited
Ding Ning   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Objet indestructible

open access: yes, 1922
Man Ray made the first version of this object shortly after his companion, the American photographer and model Lee Miller, left him. Attaching a photograph of Miller’s eye to the metronome, he linked his memory of her to the idea of an insistent beat or ...
Man Ray
core  

The Beaver, 1993 - 1994, Ray City School Yearbook

open access: yes, 1994
The Beaver, Ray City School Yearbook, 1993 - 1994. 1 electronic record (PDF), 5.61 MB (5,886,348 bytes).The Beaver, Ray City School Yearbook, 1993 - 1994. Ray City School. CA014-001: Ray City Community Library, 1952–1994 Series.
Ray City Community Library
core   +1 more source

Thymic Carcinoid Tumour

open access: yesCanadian Respiratory Journal, 2002
Carcinoid tumours of the thymus are rare. The case of a 57-year-old asymptomatic man with a carcinoid tumour of the thymus, who showed a widened mediastinum by chest x-ray, is presented. Fine needle aspiration suggested the diagnosis, which was confirmed
Isabel Parra   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Strategie di opacizzazione dell’immagine e prassi enunciative nel discorso fotografico. A partire da tre “ritratti” di Man Ray

open access: yesE|C, 2020
The paper proposes a critical overview of the concept of the enunciative praxis, in relation also to a semiotic theory of image. A critical review is followed by a second part in which a close examination is addressed to three photos by Man Ray.
Francesca Polacci
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Sushi Man [PDF]

open access: yes, 1997
Sush
Sushi Man
core  

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