Results 61 to 70 of about 943,855 (206)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
X-ray spectra and time variability of active galactic nuclei [PDF]
The X-ray spectra of broad line active galactic nuclei (AGN) of all types (Seyfert I's, NELG's, broadline radio galaxies) are well fit by a power law in the .5 to 100 keV band of man energy slope alpha = .68 + or - .15.
Mushotzky, R. F.
core +1 more source
Two judicial postmortems that went awry 1870 & 1908 [PDF]
, 1996 The first instance of an exhumation of a cadaver for a judicial post-mortem took place in 1870 in connection with a murder case. Knowledge, on the part of the pathologist, of the scene of the crime and of the events leading to the murder are important as
Cassar, Paul
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
DéméterCette étude de deux pièces peu connues de Man Ray cherche à saisir pourquoi et comment elles seraient porteuses d’une « radicalité absolue ». Ces deux pièces noires de 1929 et 1930, presque identiques, ont la particularité d’être à la fois des ...
Vincent Bonnet
doaj +1 more source
Case File: Use of POCUS for assessment of dyspnea in the Emergency Department
POCUS Journal, 2016 A 65 year-old man presented to the Emergency Department at Kingston General Hospital with progressive shortness of breath, fatigue, dull chest discomfort that worsened with deep breathing and exertion.
Jennifer Meloche
doaj +1 more source
The lambda sign in gallium‐67 scintigraphy is a useful clue to the early diagnosis of sarcoidosis
Clinical Case Reports, 2020 A 40‐year‐old man with bilateral hilar lymphadenopathy in chest X‐ray and the λ‐sign in gallium‐67 scintigraphy was subsequently diagnosed with systemic sarcoidosis according to the findings of bronchoalveolar lavage and histopathological examinations of
Yoshio Hisata +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Journal of Arrhythmia, 2019 A 51‐year‐old man with dextrocardia and complete situs inversus who presented with palpitation as a result of drug refractory paroxysmal atrial fibrillation (AF) was referred to our hospital for catheter ablation.
Shunsuke Miyauchi +7 more
doaj +1 more source
A digital algorithm for spectral deconvolution with noise filtering and peak picking: NOFIPP-DECON [PDF]
Noise-filtering, peak-picking deconvolution software incorporates multiple convoluted convolute integers and multiparameter optimization pattern search.
Edwards, T. R. +2 more
core +1 more source