Results 71 to 80 of about 3,469,267 (257)

Kay Boyle and Mary Reynolds: Friendship Intensified by War

open access: yesE-REA, 2013
In this article, I explore the friendship that existed between Kay Boyle and Mary Reynolds, primarily during World War II. For both of them, their engagement in the war, Boyle as an anti-Fascist fiction writer, and Reynolds as a participant in the French
Page DOUGHERTY DELANO
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Dynamics of medical exposure of the population of the Rostov region for the period 2019-2024

open access: yesРадиационная гигиена
The contribution of medical exposure to the collective effective dose is increasing both in the Russian Federation and in the Rostov Region, as confirmed by the results of the annual radiation-hygienic passportization.   The objective of this study is to
M. V. Kalinina   +5 more
doaj   +1 more source

Acute amiodarone pulmonary toxicity in a patient with acute anterior wall myocardial infarction and ventricular tachycardia

open access: yesSahel Medical Journal, 2013
Acute amiodarone pulmonary toxicity is a rare cause of acute respiratory distress in intensive care units. A 52-year-old man developed acute respiratory distress following intravenous amiodarone administration for refractory ventricular tachycardia.
Vijayakumar Subban   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

CHỌN TẠO GIỐNG LÚA CHẤT LƯỢNG CAO CHO ĐỒNG BẰNG SÔNG CỬU LONG GIAI ĐOẠN 2006-2008

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2010
Trước tình hình dịch hại do rầy nâu lan truyền trong các năm vừa qua, chọn giống lúa vượt trội về năng suất, phẩm chất, chống chịu rầy nâu, thích nghi vùng đất phù sa, phèn mặn là một thách thức đặt ra không nhỏ cho các nhà chọn tạo giống.
Phạm Thị Phấn   +3 more
doaj  

May Ray as an Artist and Photographer: Problems of Self-identification

open access: yesИзвестия Уральского федерального университета. Серия 2: Гуманитарные науки, 2018
This article considers the problems of self-identification by Man Ray (1890–1976) as a painter and photographer in the first half of the 20th century, the era of formation of a new aesthetic paradigm that included the de-mythologisation of the artist and 
Оlga Nikolayevna Averyanova
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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