Results 31 to 40 of about 19,556,464 (342)
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
This Special Edition of the GHMJ (Global Health Management Journal) presents six diverse studies that reflect the breadth of health challenges across Indonesia, addressed at the 1st Cirebon International Health Symposium (Vol.8, No.2s, 2025).
GHMJ (Global Health Management Journal)
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Talent Management and Career Management
This chapter explores the assumptions about Talent Management (TM) held in the TM versus the career management literature, highlighting areas of overlap and contradiction, and their implications for research and practice. The historical evolution of the global economy, from being centered mostly around agriculture to the postmodern information era, has
Marescaux, Elise+2 more
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The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source
Reviewer Acknowledgements: GHMJ (Global Health Management Journal), Volume 8, Number 1, 2025
As GHMJ (Global Health Management Journal) celebrates its 8th anniversary, we take this opportunity to express our deepest gratitude to the dedicated reviewers whose expertise and insights have significantly contributed to the quality and integrity of ...
GHMJ (Global Health Management Journal)
doaj +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
GHMJ (Global Health Management Journal) is proud to announce the successful publication of 18 high-quality articles across the first, second, and third editions of its seventh year. Each published article represents the culmination of a rigorous process,
GHMJ (Global Health Management Journal)
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Managing managers: the evolving management story in context [PDF]
Griffith Business School, Dept of Employment Relations and Human Resources ; No Full ...
Wilkinson, A, Townsend, K, Suder, G
openaire +3 more sources