Results 31 to 40 of about 19,556,464 (342)

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Reviewer Acknowledgements and Editorial Highlights: Bridging Clinical Insights and Public Health Solutions - GHMJ (Global Health Management Journal), Volume 8, Number 2s, 2025

open access: yesGHMJ (Global Health Management Journal)
This Special Edition of the GHMJ (Global Health Management Journal) presents six diverse studies that reflect the breadth of health challenges across Indonesia, addressed at the 1st Cirebon International Health Symposium (Vol.8, No.2s, 2025).
GHMJ (Global Health Management Journal)
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Talent Management and Career Management

open access: yes, 2021
This chapter explores the assumptions about Talent Management (TM) held in the TM versus the career management literature, highlighting areas of overlap and contradiction, and their implications for research and practice. The historical evolution of the global economy, from being centered mostly around agriculture to the postmodern information era, has
Marescaux, Elise   +2 more
openaire   +4 more sources

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Reviewer Acknowledgements: GHMJ (Global Health Management Journal), Volume 8, Number 1, 2025

open access: yesGHMJ (Global Health Management Journal)
As GHMJ (Global Health Management Journal) celebrates its 8th anniversary, we take this opportunity to express our deepest gratitude to the dedicated reviewers whose expertise and insights have significantly contributed to the quality and integrity of ...
GHMJ (Global Health Management Journal)
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Reviewer Acknowledgements: GHMJ (Global Health Management Journal), Volume 7, Editions 1, 2, and 3, 2024

open access: yesGHMJ (Global Health Management Journal)
GHMJ (Global Health Management Journal) is proud to announce the successful publication of 18 high-quality articles across the first, second, and third editions of its seventh year. Each published article represents the culmination of a rigorous process,
GHMJ (Global Health Management Journal)
doaj   +1 more source

Managing managers: the evolving management story in context [PDF]

open access: yes, 2015
Griffith Business School, Dept of Employment Relations and Human Resources ; No Full ...
Wilkinson, A, Townsend, K, Suder, G
openaire   +3 more sources

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