Results 61 to 70 of about 20,384,351 (344)

Understanding the outcome and management of children aged 2–59 months with chest indrawing pneumonia: a study protocol for an observational study in Ethiopia, India, Nigeria, Pakistan, Uganda and Zambia

BMJ Open
Introduction Childhood pneumonia is a leading cause of morbidity and mortality among children aged 2–59 months, particularly in low-income and middle-income countries (LMICs), where healthcare providers face significant challenges in diagnosing and ...
Chest Indrawing Pneumonia Management (CIPAM) Study Group
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Promoting cooperation through management of transboundary water resources [PDF]

Water resource managementInternational watersRiver basin managementInternational ...
International Water Management Institute (IWMI).
core  

Haste, Pressure and Staffing Shortages Contribute to Costly Mistakes

Journal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea [PDF]

, 2017
Andi L. Shane, Rajal K. Mody, John A. Crump, Phillip I. Tarr, Theodore S. Steiner, Karen L. Kotloff, Joanne M. Langley, Christine Wanke, Cirle A. Warren, Allen Cheng, J. Robert Cantey, Larry K. Pickering   +11 more
openalex   +1 more source

Recent Advances in the Management of Clear Cell Renal Cell Carcinoma: Novel Biomarkers and Targeted Therapies [PDF]

, 2023
Valentina Schiavoni, Roberto Campagna, Valentina Pozzi, Monia Cecati, Giulio Milanese, Davide Sartini, Eleonora Salvolini, Andrea Benedetto Galosi, Monica Emanuelli   +8 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Helping restore the quality of drinking water after the tsunami [PDF]

Drinking water / Tsunamis / Rehabilitation / Wells / Water quality / Salinity / Sri ...
International Water Management Institute (IWMI).
core  

Water Figures Asia: news of IWMI’s work in Asia [PDF]

Watersheds, Erosion, Land use, Groundwater, Governance, Training, Asia ...
International Water Management Institute (IWMI).
core   +3 more sources

Seek Guidance for Complex Practice Challenges: Ethics, Financial Protection and Employee Relations

Journal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source