Results 71 to 80 of about 19,857,030 (343)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

IWMI medium term plan 2010-2012 [PDF]

Research institutes / Strategy planning / Financial situation / Research priorities / Research projects / Project planning / Maintenance costs / Water resource management / Irrigated ...
International Water Management Institute (IWMI).
core  

Retracted: Effects of Scrambler Therapy in Patients with Failed Back Surgery Syndromes and Factors Associated with Depression Affecting Pain before and after the Therapy

Pain Research and Management, 2021
Pain Research and Management
doaj   +1 more source

Management of the Pregnant Diabetic [PDF]

, 1955
John Peel
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Promoting cooperation through management of transboundary water resources [PDF]

Water resource managementInternational watersRiver basin managementInternational ...
International Water Management Institute (IWMI).
core  

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Helping restore the quality of drinking water after the tsunami [PDF]

Drinking water / Tsunamis / Rehabilitation / Wells / Water quality / Salinity / Sri ...
International Water Management Institute (IWMI).
core  

Standard for Organization Construction and Management of Rehabilitation Institutions

康复学报, 2022
National-level, provincial-level, prefectural-level, county-level rehabilitation centers and a large number of community-based rehabilitation institutions have been established in my country, basically forming a nationwide network of rehabilitation ...
Working Group of Standard for Organization Construction and Management of Rehabilitation Institutions
doaj  

The Management of Pulmonary Tuberculosis [PDF]

, 1950
F. H. Young
openalex   +1 more source