Results 71 to 80 of about 19,556,464 (342)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Water Figures Asia: news of IWMI’s work in Asia [PDF]
Water policy, Water pollution, Land degradation, Land use, Asia ...
International Water Management Institute (IWMI).
core +3 more sources
Promoting cooperation through management of transboundary water resources [PDF]
Water resource managementInternational watersRiver basin managementInternational ...
International Water Management Institute (IWMI).
core
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Role of Managers in Management of Change
Procedia Economics and Finance, 2014 AbstractWhen changes occur, managers and supervisors may be their biggest supporters, but also the biggest opponents. They are closest to the employees who need to support new processes and behaviors caused by changes. In many cases, the changes will affect the work and position of managers and supervisors.Managers and supervisors play a key role ...
Eduard-Ionel Ionescu +2 more
openaire +2 more sources
Helping restore the quality of drinking water after the tsunami [PDF]
Drinking water / Tsunamis / Rehabilitation / Wells / Water quality / Salinity / Sri ...
International Water Management Institute (IWMI).
core
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Standard for Organization Construction and Management of Rehabilitation Institutions
康复学报, 2022 National-level, provincial-level, prefectural-level, county-level rehabilitation centers and a large number of community-based rehabilitation institutions have been established in my country, basically forming a nationwide network of rehabilitation ...
Working Group of Standard for Organization Construction and Management of Rehabilitation Institutions
doaj