Results 131 to 140 of about 18,384,957 (344)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The need for a risk management framework for data science projects: a systematic literature review
International Journal of Information Systems and Project ManagementMany data science endeavors encounter failure, surfacing at any project phase. Even after successful deployments, data science projects grapple with ethical dilemmas, such as bias and discrimination.
Sucheta Lahiri, Jeff Saltz
doaj +1 more source
Notes on the Markowitz portfolio selection method [PDF]
Portfolio Investment;management ...
Kriens, J., Lieshout, J.T.H.C. van
core +1 more source
Herbicide-Resistant Soybeans in Arkansas: Lessons Learned and Future Direction [PDF]
, 2013 In Arkansas Delta soybean production, glyphosate resistant (GR) Palmer amaranth has significantly impacted weed management. The incidence of herbicide resistant (HR) weeds has farreaching crop science, economic, and communications implications, which ...
Bough, Raven +6 more
core +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Lithuanian women in science: management facets
Business: Theory and Practice, 2008 Though the proportion of women community in Lithuanian science and research and the interest in this phenomenon by representatives of different scientists are growing, yet the many unsolved or inefficiently solved problems, from thepoint of view of ...
Ina Dagytė
doaj
Optimal dynamic investment policy under financial restrictions and adjustment costs [PDF]
Management ...
Kort, P.M.
core +1 more source
Arkansas Animal Science Department Report 2002 [PDF]
, 2002 The faculty and staff of the Animal Science Program are pleased to present the sixth edition of the Arkansas Animal Science Report. As with virtually all programs in the country, budget constraints presented serious challenges to teaching, research, and ...
Johnson, Zelpha B., Kellogg, D. Wayne
core +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source