Results 141 to 150 of about 6,565,603 (355)
Investigating several alternatives for estimating the compound lead time demand in an (s,Q) inventory model [PDF]
Inventory Models;management ...
Heuts, R.M.J., Strijbosch, L.W.G.
core +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Research on Application of Information Management and Management Science in Economic Activities [PDF]
, 2018 Songwen Fang
openalex +1 more source
Modeling Scientists as Agents. How Scientists Cope with the Challenges of the New Public Management of Science [PDF]
The paper at hand applies agent-based modeling and simulations (ABMS) as a tool to reconstruct and to analyze how the science system works. A Luhmannian systems perspective is combined with a model of decision making of individual actors.
Johannes Weyer +2 more
core
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Enabling data‐driven collaborative and reproducible environmental synthesis science
Methods in Ecology and EvolutionThis manuscript shares the lessons learned from providing scientific computing support to over 600 researchers and discipline experts, helping them develop reproducible and scalable analytical workflows to process large amounts of heterogeneous data ...
Julien Brun +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source