Results 51 to 60 of about 7,019,823 (296)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Research on optimal power source for passenger transport eVTOL

open access: yesNihon Kikai Gakkai ronbunshu
eVTOL is anticipated to be a new mode of passenger transportation, with battery-powered systems frequently being considered due to their simple architecture, ease of maintenance, and zero in-flight emissions.
Shigetoshi TOKUOKA   +2 more
doaj   +1 more source

A Novel Hybrid Home Energy Management System Considering Electricity Cost and Greenhouse Gas Emissions Minimization [PDF]

open access: hybrid, 2021
Sara Barja-Martínez   +5 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Management system for building production with multi-layer simultaneous auctions

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2014
Building production can be regarded as a one-piece production because not only specifications of individual buildings but also working environment for them are different.
Hidefumi WAKAMATSU   +2 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Quality Management System

open access: yesJournal of Clinical and Biomedical Sciences, 2021
Subhashish Das
doaj   +1 more source

Research on the optimization of coal mine safety production management system —take a coal mine in Shaanxi as an example

open access: yes矿业科学学报, 2019
Taking a coal mine in Shaanxi province as an example,this paper made an optimization study of its existing safe production management system.In full field investigation,the paper investigated the current situation of the safe production management system
Song Xi   +3 more
doaj   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

open access: yesMolecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat   +18 more
wiley   +1 more source

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