Results 21 to 30 of about 2,064 (197)
Acute toxicity of maneb in the tadpoles of common and green toad [PDF]
, 2015 Pesticides used in agriculture can have hazardous effects on aquatic organisms, and amphibians are even more threatened than other aquatic vertebrates. Maneb is widely used to control fungal diseases on crops, fruits, and vegetables.
Hayretdag, Sibel, Gurkan, Mert
core +3 more sources
Acta Pharmaceutica, 2022 Parkinson’s disease (PD) is the second most prevalent neuro-degenerative disease after Alzheimer´s disease. It is characterized by motor symptoms such as akinesia, bradykinesia, tremor, rigidity, and postural abnormalities, due to the loss of nigral ...
Casanova Yaquelyn +2 more
doaj +1 more source
Reasoned opinion on the modification of the existing MRLs for dithiocarbamates (expressed as carbon disulfide) in bulb vegetables, cucurbits and asparagus [PDF]
EFSA Journal, 2012 <p>In accordance with Article 6 of Regulation (EC) No 396/2005, Italy, herewith referred to as the evaluating Member State (EMS), received an application from the company BASF Italia Srl. to modify the existing MRLs for dithiocarbamate in cucurbits
European Food Safety Authority
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Genome-Wide Meta-Analysis of Parkinson's Disease Associated Genetic Loci and Validation of Therapeutic Targets. [PDF]
Brain BehavThis study identified genetic loci associated with Parkinson's disease through a genome‐wide meta‐analysis, screened druggable genes significantly linked to PD risk, and assessed the potential of GCLC and GFPT1 as therapeutic targets. ABSTRACT Background To identify genetic loci associated with Parkinson's disease (PD) through a genome‐wide meta ...
Yang S, Wu Q, Yang X.
europepmc +2 more sources
Assessment of Pesticide Residue Content in Polish Agricultural Soils
Molecules, 2020 Pesticides belong to a group of xenobiotics harmful to humans and wildlife, whose fate and activity depends on their susceptibility to degradation.
Aleksandra Ukalska-Jaruga +2 more
doaj +1 more source
Translational Neuroscience, 2022 Exposure to pesticides in humans increases the risk of Parkinson’s disease (PD), but the mechanisms remain poorly understood. To elucidate these pathways, we dosed C57BL/6J mice with a combination of the pesticides maneb and paraquat. Behavioral analysis
Khan Arshad H. +2 more
doaj +1 more source
Sulphonylureas as Adjunct Therapeutic Agents in the Treatment of Autoimmune Conditions: A Narrative Review. [PDF]
Pharmacol Res PerspectNLRP3 Inflammasome activation drives inflammatory responses through the production and activation of pro‐inflammatory cytokines. Repurposing sulphonylureas and their derivatives to target NLRP3 may act as adjunct therapeutics for autoimmune conditions. ABSTRACT A rapid and cost‐effective arm of the drug discovery and development process is finding new ...
Elford J +4 more
europepmc +2 more sources
Redox Biology, 2019 The activation of NADPH oxidase contributes to dopaminergic neurodegeneration and motor deficits in Parkinson's disease (PD). However, whether NADPH oxidase is involved in non-motor symptoms, especially cognitive dysfunction in PD remains unknown.
Liyan Hou +5 more
doaj +1 more source
Redox Biology, 2018 Microglial NADPH oxidase (Nox2) plays a key role in chronic neuroinflammation and related dopaminergic neurodegeneration in Parkinson's disease (PD). However, the mechanisms behind Nox2 activation remain unclear.
Liyan Hou +8 more
doaj +1 more source
Silver Against the Coronavirus Epidemic = Серебро против эпидемии коронавирусов
Journal of Education, Health and Sport, 2020 All over the world, research is currently underway aimed at finding the means of treatment and prevention of Covid-19 coronavirus disease . In such a situation, any new or long-known idea may be valuable.The purpose of this article is to draw the ...
Аnatoliy Zhukov, Walery Zukow
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