Results 91 to 100 of about 783,178 (384)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Fungicide resistance among Cladobotryum spp. – causal agents of cobweb disease of the edible mushroom Agaricus bisporus [PDF]

, 2000
A survey of fungicide resistance among isolates of the mushroom pathogens Cladobotryum mycophilum and C. dendroides Types I and II was undertaken, with respect to the active ingredients thiabendazole, carbendazim (benzimidazoles) and prochloraz manganese
Bonnen, Cole, Davidse, De Hoog, Fletcher, Fletcher, Fletcher, Fujimura, Gams, Gaze, Gaze, Hassall, Helen M. Grogan, McKay, McKay, Richard H. Gaze, Rogerson, Rogerson, Sharma, Sinden   +19 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Partitioning of trace metals between soft tissues and shells of Patella aspera [PDF]

, 2004
This paper describes the partitioning of iron, manganese, zinc, copper, cadmium, cobalt, nickel and lead between the soft tissues and the shells of the gastropod mollusc Patella aspera. Specimens of the limpet P aspera were collected from a clean coastal
Bebianno, Maria João, Cravo, Alexandra, Foster, P.   +2 more
core   +1 more source

Packing polymorphism in the structure of trans-aqua[N,N′-bis(salicylidene)ethane-1,2-diamine-κ4O,N,N′,O′]chloridomanganese(III) monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2018
The crystal structure of the title complex (systematic name: trans-aquachlorido{2,2′[ethane-1,2-diylbis(nitrilomethylidyne)]diphenolato-κ4O,N,N′,O′}manganese(III) monohydrate), [Mn(C16H14N2O2)Cl(H2O)]·H2O has been reported previously in the space group ...
Juan Alberto Reyes Perea, Sylvain Bernès, Ma Guadalupe Quintero Téllez   +2 more
doaj   +1 more source

Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics.

ACS Nano, 2018
Ferroptosis, an iron-based cell-death pathway, has recently attracted great attention owing to its effectiveness in killing cancer cells. Previous investigations focused on the development of iron-based nanomaterials to induce ferroptosis in cancer cells
Shuaifei Wang, Fangyuan Li, Ruirui Qiao, Xi Hu, Hongwei Liao, Lumin Chen, Jiahe Wu, Haibin Wu, Meng Zhao, Jianan Liu, Rui Chen, Xibo Ma, Dokyoon Kim, Jihong Sun, T. P. Davis, Chunying Chen, Jie Tian, T. Hyeon, D. Ling   +18 more
semanticscholar   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Large Magnetic Moments of Arsenic-Doped Mn Clusters and their Relevance to Mn-Doped III-V Semiconductor Ferromagnetism [PDF]

, 2005
We report electronic and magnetic structure of arsenic-doped manganese clusters from density-functional theory using generalized gradient approximation for the exchange-correlation energy.
Abhijit Mookerjee, D. G. Kanhere, M. D. Morse, Mukul Kabir, Y. Yamaguchi   +4 more
core   +2 more sources

Synthèse et structure cristalline d'un matériau noir AgMnII3(MnIII0,26Al0,74)(MoO4)5

Acta Crystallographica Section E: Crystallographic Communications, 2015
A new silver aluminium trimanganese pentamolybdate {silver(I) trimanganese(II) aluminium pentakis[tetraoxidomolybdate(VI)]}, AgMnII3(MnIII0,26Al0,74)(MoO4)5, has been synthesized using solid-state methods. The structure is composed of M2O10 dimers, M3O14
Chahira Bouzidi, Wafa Frigui, Mohamed Faouzi Zid   +2 more
doaj   +1 more source

Phosphorescent Manganese(II) Complexes and Their Emerging Applications

Advanced Optical Materials, 2020
Phosphorescent manganese(II) complexes are emerging as a new generation of phosphorescent materials showing great potentials in many applications, owing to their unique features including highly efficient phosphorescence, diverse structural/molecular ...
Peng Tao, Shu-juan Liu, W. Wong
semanticscholar   +1 more source