Results 91 to 100 of about 416,214 (338)

Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein

Science Signaling, 2019
Manganese exposure promotes α-synuclein propagation, neuroinflammation, and neurodegeneration. Manganese in Parkinson’s disease Manganese is an essential mineral, but chronic exposure to high amounts of it, such as is experienced by welders, is ...
Dilshan S. Harischandra, Dharmin Rokad, Matthew L. Neal, Shivani Ghaisas, Sireesha Manne, Souvarish Sarkar, Nikhil Panicker, G. Zenitsky, Huajun Jin, M. Lewis, Xuemei Huang, V. Anantharam, A. Kanthasamy, A. Kanthasamy   +13 more
semanticscholar   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Leaf-associated bacterial microbiota of coffee and its correlation with manganese and calcium levels on leaves

Genetics and Molecular Biology, 2018
Coffee is one of the most valuable agricultural commodities and the plants’ leaves are the primary site of infection for most coffee diseases, such as the devastating coffee leaf rust.
Leandro Pio de Sousa, Marcio José da Silva, Jorge Maurício Costa Mondego   +2 more
doaj   +1 more source

Manganese [PDF]

Advances in Nutrition, 2017
Michael, Aschner, Keith, Erikson
openaire   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Determination of plant-available manganese in Finnish soils

Agricultural and Food Science, 1981
The aim of the study was to determine the plant-available manganese in the soil and to study which factors regulate the plant-available manganese. The material consisted of 193 mineral soils and 17 organogenic soils.
Väinö Mäntylahti
doaj  

Chemical Heterogeneity of Mg, Mn, Na, S, and Sr in Benthic Foraminiferal Calcite

Frontiers in Earth Science, 2019
The chemical composition of fossil foraminiferal shells (tests) is widely used as tracers for past ocean chemistry. It is, therefore, important to understand how different (trace) elements are transported and incorporated into these tests from adjacent ...
Inge van Dijk, Aurélia Mouret, Marine Cotte, Marine Cotte, Sandrine Le Houedec, S. Oron, S. Oron, Gert-Jan Reichart, Gert-Jan Reichart, Juan Reyes-Herrera, Juan Reyes-Herrera, Helena L. Filipsson, Christine Barras   +12 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source