Results 111 to 120 of about 76,451 (278)

Psychotropic Prescribing Patterns Among Bipolar‐I Patients Prior to Established Bipolar‐I Disorder Diagnosis

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objective Bipolar I Disorder (BP‐I) is frequently misdiagnosed as Major Depressive Disorder (MDD), delaying appropriate treatment. This study aimed to examine treatment patterns among BP‐I patients misdiagnosed with MDD and assess the impact of these regimens on the time until BP‐I diagnosis.
Filmon Haile, Clayton English, Kyueun Lee   +2 more
wiley   +1 more source

The Genetics of Depression and Manic-Depressive Disorder

, 1989
Depressive disorders are more common in the relatives of depressed probands than in the population at large, and there is compelling evidence that the familial aggregation of bipolar disorder and severe unipolar depression is at least partly due to ...
Peter McGuffin, Randy Katz
core   +1 more source

Can We Improve the Prediction of Early Onset Mania and Hypomania in the Community?

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background There is broad agreement that the onset of bipolar disorders (BD) can be predicted by using combined estimates of familial, genetic and clinical risk. However, there is a lack of consensus about the operationalisation of different risk attributes (e.g., symptoms vs.
Jan Scott, Jacob J. Crouse, Sarah E. Medland, Brittany L. Mitchell, Nathan A. Gillespie, Nicholas G. Martin, Ian B. Hickie   +6 more
wiley   +1 more source

Epigenetic Age Accelerations and the Clinical Presentation of Bipolar Disorders: A Latent Profile Analysis in the FACE‐BD Sample

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background Epigenetic age accelerations have been associated with the clinical expression of BD; however, with few available studies. Method We calculated Horvath, Hannum, EN, GrimAge, and PhenoAge epigenetic ages in a sample of 139 individuals with BD.
Luana Spano, Céline Bourdon, Mohamed Lajnef, Ophélia Godin, Marion Leboyer, Katia M'Bailara, Antoine Lefrere, Raoul Belzeaux, Philippe Courtet, Emilie Olie, Caroline Dubertret, Raymund Schwan, Paul Roux, Mircea Polosan, Ludovic Samalin, FondaMental Advanced Centers of Expertise in Bipolar Disorders (FACE‐BD) Collaborators, B. Etain, E. Olié, M. Leboyer, E. Haffen, P. M. Llorca, V. Barteau, S. Bensalem, O. Godin, S. Hotier, A. Macone, A. Pelletier, C. Pin, C. Dominique, C. Lam, J. Lantier, F. Harter, V. Nicolaidis, F. Bellivier, B. Etain, V. Hennion, E. Marlinge, B. Aouizerate, N. Da Ros, C. Elkael, S. Gard, F. Hoorelbcke, K. M'Bailara, I. Minois, J. Sportich, M. Benramdane, L. Boukhobza, P. Courtet, B. Deffinis, D. Ducasse, M. Gachet, E. Olié, E. Palmeri, G. Tarquini, M. Cermolacce, A. Lefrere, E. Moreau, H. Polomeni, F. Groppi, J. Baurberg, L. Lescalier, I. Murracioli, A. Surray, E. Cosker, R. Schwan, A. Bertrand, J. Pastol, B. Fredembach, Q. Denoual, E. Winiarski, A. Pouchon, M. Polosan, C. Passerieux, L. Brehon, L. Durand, S. Frileux, V. Feuga, P. Roux, E. Vaux, C. Dubertret, N. Mazer, P. Laurent, C. Beal, O. Blanc, T. Bonnet, M. Gambier, C. Garcin, D. Lacelle, P. M. Llorca, L. Samalin, Frank Bellivier, Cynthia Marie‐Claire, Bruno Etain   +92 more
wiley   +1 more source

Continuum of Depressive and Manic Mixed States In Patients With Bipolar Disorder: Quantitative Measurement and Clinical Features

, 2009
Bipolar mixed states combine depressive and manic features, presenting diagnostic and treatment challenges and reflecting a severe form of the illness.
GERARD F. MOELLER, Moeller, Gerard F, ALAN C. SWANN, Steinberg, Joel L, Lijffijt, Marijn, MARIJN LIJFFIJT, Swann, Alan C, JOEL L. STEINBERG   +7 more
core   +1 more source

The Theory of Metabolic Jet Lag in Bipolar Disorder: A Pilot Feasibility Study Exploring the Association Between Eating Rhythm Disruption and Illness Burden Parameters

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Introduction Changes in energy metabolism are commonly observed in bipolar disorder (BD) and have been linked to a more severe clinical course. ‘Metabolic jet lag’ (MJL) is a state of shift in circadian patterns of energy homeostasis, expressed through behavioral changes such as irregular meal timing.
Elena Koning, Vitor Breda, Sareh Panjeh, Elisa Brietzke   +3 more
wiley   +1 more source

Time Trends in Excess Mortality Among Individuals With Bipolar Disorder in Finland, 2000–2023: A Nationwide Register Study

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objectives To investigate excess all‐cause mortality among individuals with bipolar disorder in Finland and examine time trends in the mortality gap between individuals with bipolar disorder and the general population during 2000–2023. Methods Individuals diagnosed with bipolar disorder during 1975–2023 in Finland were identified using the ...
Julia Rimmington, Sonja Lumme, Kimmo Suokas, Mai Gutvilig, Marko Elovainio, Christian Hakulinen   +5 more
wiley   +1 more source

The post-viral fatigue syndrome [PDF]

, 1990
Post-viral fatigue syndrome (myalgic encephalomyelitis) is a physically debilitating disorder associated with chronic disabling fatigue. This thesis presents two studies which look at the impact of illness from a personal-psychological and from a family ...
Procter, C.A, Procter, Charlotte Anne
core  

Intensive Home Treatment in Mental Health: A Qualitative Exploration of Carers' Experiences

International Journal of Mental Health Nursing, Volume 35, Issue 4, August 2026.
ABSTRACT Intensive Home Treatment for acute mental health crises has expanded internationally as a community‐based alternative to inpatient admission. Despite its growing use, little is known about how informal carers experience supporting a relative during acute psychiatric decompensation at home—an emotionally demanding context marked by intensified ...
Alba González‐Fernández, Ana Martín‐Blanco, Francesc Casanovas, Alba Luque Tintó, Denise Cid Matamoros, Joan Trujols, Maria J Portella, David Giménez‐Díez   +7 more
wiley   +1 more source

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 1957-1976, July 2026.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway, Cinzia Dello Russo, Nicholas Bass, Elvira Bramon, Helen Cross, Natalie Curley, Sarah Curran, Helen Davies, Jana De Villiers, William Evans, Bernhard Frank, Alice Groves, Judith Hayward, Jon Higham, Dyfrig A. Hughes, Shwe Sin Kyaw, Anthony G. Marson, Ailsa McLellan, Seth Mensah, Francis O'Neill, Jane Sargison, Sanjay M. Sisodiya, Jill Swan, Joanna M. Zakrewska, Munir Pirmohamed   +24 more
wiley   +1 more source